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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Prostate Active Surveillance Study

for
Prostatic Neoplasms
Location: Boston MA, Norfolk VA, Atlanta GA, Ann Arbor MI,
Sponsor: University of Washington

Sex: Male

Age: 21+

Code: NCT00756665

Recruiting

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

for
Non Hodgkin Lymphoma (NHL), Mantle Cell Lymphoma (MCL),
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18 - 70+

Code: NCT04186520

Phase1, Phase2, Recruiting

Prospective Breast Cancer Biospecimen Collection

for
Breast Cancer, Invasive Breast Cancer,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT04074720

Recruiting

A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL

for
Relapsed Hodgkin Lymphoma, Refractory Hodgkin Lymphoma,
Location: Indianapolis IN
Sponsor: Rita Assi

Sex: All

Age: 18+

Code: NCT06484920

Phase2, Recruiting

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

for
Colorectal Cancer, Pancreatic Cancer, Gastric Cancers,
Location: Montreal, Ottawa, Toronto, Hamilton, Edmonton
Sponsor: Bold Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04421820

Phase1, Phase2, Recruiting

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Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study

for
Prostate Adenocarcinoma
Location: Pittsburgh PA, Seattle WA
Sponsor: University of Washington

Sex: Male

Age: 18+

Code: NCT04175431

Phase2, Recruiting

Extended Mesenteric Excision in Ileocolic Resections for Crohn's Disease.

for
Crohn Disease, Recurrence, Crohn's Ileocolitis
Location: Montreal
Sponsor: Montreal General Hospital

Sex: All

Age: 18+

Code: NCT04539665

Recruiting

Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy

for
Colorectal Surgery, Colorectal Cancer, Rectal/Anal,
Location: Hershey PA, Buffalo NY, Houston TX
Sponsor: JSR Medical Co., Ltd.

Sex: All

Age: 19 - 70+

Code: NCT05826743

Recruiting

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

for
Adenocarcinoma of the Rectum,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05672524

Phase2, Recruiting

Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer

for
Symptoms and Signs, Cancer, Childhood Cancer
Location: Richmond VA, Kansas City MO, Salt Lake City UT
Sponsor: Virginia Commonwealth University

Sex: All

Age: 15 - 29

Code: NCT05958316

Recruiting

Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial

for
Recurrent Chronic Lymphocytic Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT04941716

Phase2, Recruiting

Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer

for
ER-Positive Breast Cancer, HER2-negative Breast Cancer
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT05305924

Phase2, Recruiting

Alternative Dosing Of Niraparib To Decrease Dose Interruption In First Line Maintenance Treatment For Ovarian Cancer

for
Ovarian Cancer, Stage III Ovarian Cancer,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: Female

Age: 18+

Code: NCT05961124

Phase2, Recruiting

Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

for
Alcohol Use Disorder, Human Immunodeficiency Virus
Location: Chicago IL
Sponsor: Rush University Medical Center

Sex: All

Age: 45 - 70+

Code: NCT06139224

Recruiting

Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT

for
Cancer, Thoracic Cancer, Gynecologic Cancer,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06633224

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

for
High-grade Serous Ovarian Carcinoma (HGSOC),
Location: Hackensack NJ, Montreal, Toronto, Vancouver,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06476808

Phase1, Recruiting

A Study of Ivonescimab in People With Endometrial and Cervical Cancers

for
Endometrial Cancer, Cervical Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT06925724

Phase2, Recruiting

AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc

for
Breast Cancer Invasive, Prostate Cancer
Location: New York NY, Miami Beach FL
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT05351424

Recruiting

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

for
B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma,
Location: Boston MA, Quebec, New York NY, Bethesda MD,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT05006716

Phase1, Phase2, Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

for
Pancreatic Cancer, Renal Cell Cancer, Breast Cancer, Melanoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02830724

Phase1, Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer