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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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1

Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy

for
Non-small Cell Lung Cancer, Radiation Toxicity
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 0+

Code: NCT03416972

Recruiting

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients

for
Melanoma Stage III, Melanoma Stage IV
Location: Hartford CT, New York NY
Sponsor: Philogen S.p.A.

Sex: All

Age: 18+

Code: NCT06284590

Phase 2, Recruiting

CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell Transplant

for
Diffuse Large B Cell Lymphoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18 - 70+

Code: NCT06687772

Phase 2, Recruiting

Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer

for
Esophagus Adenocarcinoma, Esophagus Squamous Cell Carcinoma,
Location: Dallas TX
Sponsor: Dallas VA Medical Center

Sex: All

Age: 18+

Code: NCT04018872

Phase 2, Recruiting

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

for
Ovarian Neoplasms, Endometrial Neoplasms,
Location: Mineola NY, New York NY, Columbus OH, Grand Rapids MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06400472

Phase 1, Recruiting

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Oropharynx (OPX) Biomarker Trial

for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06356272

Recruiting

BostonGene and Exigent Genomic INsight Study

for
Breast Cancer, Non-small Cell Lung Cancer, Melanoma, Sarcoma
Location: Fort Wayne IN, Rogers AR, Houston TX, Tulsa OK,
Sponsor: BostonGene

Sex: All

Age: 18+

Code: NCT06272864

Recruiting

Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors

for
Metastatic Pancreatic Neuroendocrine Tumor
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06663072

Phase 1, Recruiting

A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC)

for
Metastatic Renal Cell Carcinoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06835972

Phase 1, Phase 2, Recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

for
HPV-Associated Cervical Carcinoma, HPV-Related Carcinoma,
Location: New Brunswick NJ
Sponsor: Christian Hinrichs

Sex: All

Age: 18+

Code: NCT05639972

Phase 1, Phase 2, Recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

for
Gastroesophageal Junction, Gastroesophageal Adenocarcinoma,
Location: East Syracuse NY, Pittsburgh PA, Grand Rapids MI,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06445972

Phase 1, Phase 2, Recruiting

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

for
Colorectal Cancer, CRC
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT06728072

Phase 2, Recruiting

Assessing the Utility of Ultrasound Compared to Cross-Sectional Imaging in the Follow-up of Patients With Renal Cell Carcinoma

for
Renal Cell Carcinoma
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT04424472

Recruiting

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

for
Colorectal Adenocarcinoma, Stage I Colorectal Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04739072

Recruiting

Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.

for
Ovarian Cancer, Breast Cancer, Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05649072

Recruiting

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

for
Non-muscle Invasive Bladder Cancer
Location: Plymouth MA, Boston MA, The Bronx NY, New York NY,
Sponsor: Protara Therapeutics

Sex: All

Age: 18+

Code: NCT05951179

Phase 2, Recruiting

Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation

for
Extensive Stage Lung Small Cell Carcinoma, Stage IV Lung Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06110572

Phase 1, Phase 2, Recruiting

Microwave Ablation of Primary and Secondary Lung Malignancies

for
Lung Neoplasms, Neoplasm Metastasis
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT04369872

Phase 1, Phase 2, Recruiting

Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes

for
Hereditary Colorectal Cancer Syndrome
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02863172

Recruiting

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

for
Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma,
Location: Boston MA, Chapel Hill NC, Columbus OH, Cincinnati OH,
Sponsor: Newave Pharmaceutical Inc

Sex: All

Age: 13+

Code: NCT04771572

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer