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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

for
Biochemically Recurrent Prostate Carcinoma,
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: Male

Age: 18+

Code: NCT06205316

Phase3, Recruiting

Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients

for
Triple Negative Breast Cancer, Vitamin D Deficiency,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT04677816

Phase2, Recruiting

Gastrointestinal Microbiome Study of Appendiceal Cancer

for
Pseudomyxoma Peritonei, Appendiceal Neoplasm,
Location: Baltimore MD
Sponsor: Mercy Medical Center

Sex: All

Age: 18 - 70+

Code: NCT02599116

Recruiting

Radiotherapy in Combination With Atezolizumab in Locally Advanced Borderline Resectable or Unresectable Cutaneous SCC

for
Locally Advanced Skin Squamous Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05085496

Phase1, Recruiting

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

for
High Grade Glioma, Meningioma, Embryonal Tumor, Medulloblastoma,
Location: Columbus OH, Cincinnati OH
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 4 - 39

Code: NCT05278208

Phase1, Phase2, Recruiting

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Molecular Analysis Of Solid Tumors

for
Pediatric Solid Tumors
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 25

Code: NCT01050296

Recruiting

CyberKnife Radiosurgery for Locally Recurrent Prostate CA

for
Recurrent Prostate Cancer
Location: San Diego CA
Sponsor: CyberKnife Centers of San Diego

Sex: Male

Age: 18+

Code: NCT00851916

Phase2, Recruiting

Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

for
Head and Neck Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT03875716

Recruiting

Metabolism and Sleep Apnea Treatment

for
Obstructive Sleep Apnea, Fat Disorder
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18 - 70

Code: NCT05539716

Recruiting

Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment

for
Liver Metastases
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04143516

Phase2, Phase3, Recruiting

Loratadine for the Prevention of G-CSF-related Bone Pain

for
Stem Cell Transplant Complications
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT05421416

Phase2, Recruiting

Survivorship Plan HEalth REcord (SPHERE) Implementation Trial

for
Cancer
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18 - 70+

Code: NCT05346796

Recruiting

Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study)

for
Postoperative Wound Infection, Postoperative Complications,
Location: Danville PA
Sponsor: Sean Devitt

Sex: All

Age: 18+

Code: NCT04725916

Recruiting

A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer

for
Hepatocellular Carcinoma
Location: Sherbrooke, Montreal, Toronto, Dothan AL, Duarte CA
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06764316

Phase1, Recruiting

Minimally-invasive Stabilization of Pelvic Metastases With Photodynamic Nails: A Multi-center Prospective Study of Functional Outcome

for
Pelvic Metastasis
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06083896

Phase1, Recruiting

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

for
Advanced Solid Tumor, Refractory Hodgkin Lymphoma
Location: Greenville SC
Sponsor: FBD Biologics Limited

Sex: All

Age: 18+

Code: NCT06487624

Phase1, Recruiting

Prehab Prior to Stem Cell Transplantation in Multiple Myeloma

for
Multiple Myeloma, Exercise, Prehabilitation
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 18+

Code: NCT06280924

Recruiting

Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT05526924

Phase1, Recruiting

Enfortumab Vedotin and Pembrolizumab in People With Bladder Cancer

for
Urothelial Carcinoma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05239624

Phase2, Recruiting

Panitumumab-IRDye800 in Detecting Cancer in Participants With Lung Cancer During Surgery

for
Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung,
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 19+

Code: NCT03582124

Phase1, Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer