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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 219 people applied to oncology studies last month. Search by city or state to find one near you.

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Commack NY, Uniondale NY, Mineola NY, Harrison NY,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06500481

Phase 3, Recruiting

A Study of Tetrathiomolybdate (TM) Plus Capecitabine

for
Triple Negative Breast Cancer, Residual Disease
Location: Lebanon NH, New York NY
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06134375

Phase 1, Phase 2, Recruiting

Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence

for
ENSAT Stage I Adrenal Cortex Carcinoma,
Location: Ann Arbor MI, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03583710

Phase 3, Recruiting

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for
Cutaneous Squamous Cell Carcinoma (CSCC)
Location: Beverly MA, Portsmouth NH, Boston MA, New York NY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06585410

Phase 3, Recruiting

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT05464810

Early Phase 1, Recruiting

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A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

for
Recurrent Head and Neck Squamous Cell Carcinoma
Location: Providence RI, Philadelphia PA, Miami FL, Tampa FL,
Sponsor: Rakuten Medical, Inc.

Sex: All

Age: 18+

Code: NCT06699212

Phase 3, Recruiting

Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy

for
Prostate Cancer
Location: Halifax, Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: Male

Age: 18+

Code: NCT05169112

Phase 3, Recruiting

Microbiome in Immunotherapy naïve NSCLC Patients Receiving PD-1/L1 Blockade (MIP_NSCLC)

for
NSCLC Stage IV, NSCLC, Recurrent
Location: Kansas City KS, Fairway KS
Sponsor: Jun Zhang, MD, PhD

Sex: All

Age: 18+

Code: NCT04636775

Recruiting

Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children

for
Pediatric ALL, Cardiac Defect
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 0 - 18

Code: NCT06529575

Recruiting

Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

for
Acute Myeloid Leukemia, B-cell Acute Lymphoblastic Leukemia,
Location: Cincinnati OH, Birmingham AL, Nashville TN, Houston TX,
Sponsor: Vincerx Pharma, Inc.

Sex: All

Age: 18+

Code: NCT06034275

Phase 1, Recruiting

An Evaluation of Polymer Based Fiducials for Use in Imaging Patients Receiving Treatment for Prostate Cancer

for
Prostate Adenocarcinoma
Location: Warrenville IL
Sponsor: John Chang, MD

Sex: Male

Age: 0+

Code: NCT01478412

Recruiting

Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation

for
Chronic Myeloproliferative Disorders, Kidney Cancer, Leukemia,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 2 - 18

Code: NCT00036712

Phase 2, Recruiting

Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies

for
Gynecologic Neoplasm, Brachytherapy, Therapeutic Touch,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Female

Age: 18+

Code: NCT05979610

Phase 2, Recruiting

Genomic Risk in Retroperitoneal Sarcoma

for
Retroperitoneal Liposarcoma, Soft Tissue Sarcoma
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT06436846

Recruiting

Long-term Outcomes Associated With Juvenile-onset Mycosis Fungoides and Lymphomatoid Papulosis

for
Lymphomatoid Papulosis, Mycosis Fungoides
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06207812

Recruiting

Digoxin Medulloblastoma Study

for
Medulloblastoma, Medulloblastoma, Non-WNT/Non-SHH
Location: Hartford CT, The Bronx NY, Baltimore MD,
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 1 - 30

Code: NCT06701812

Phase 2, Recruiting

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

for
Recurrent Melanoma (Skin), Metastatic Melanoma,
Location: Philadelphia PA, Chapel Hill NC, Miami FL,
Sponsor: Perspective Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05655312

Phase 1, Phase 2, Recruiting

Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance

for
Prostate Adenocarcinoma, Prostate Cancer
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: Male

Age: 18+

Code: NCT03933670

Phase 2, Recruiting

A Study of Administering FOLFIRINOX Before Surgery For Potentially Curable Pancreatic Cancer

for
Pancreatic Cancer
Location: Montreal
Sponsor: Petr Kavan

Sex: All

Age: 18+

Code: NCT03167112

Phase 2, Recruiting

Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma

for
Epithelial Ovarian Carcinoma
Location: Newport Beach CA
Sponsor: Gynecologic Oncology Associates

Sex: Female

Age: 18+

Code: NCT02437812

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer