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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 219 people applied to oncology studies last month. Search by city or state to find one near you.

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1

Orphan Indications for CD19 Redirected Autologous T Cells

for
Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL,
Location: Philadelphia PA
Sponsor: Stephan Grupp MD PhD

Sex: All

Age: 0 - 29

Code: NCT04276870

Phase 2, Recruiting

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

for
Diffuse Midline Glioma, H3 K27M-Mutant,
Location: Minneapolis MN
Sponsor: OX2 Therapeutics

Sex: All

Age: 2 - 25

Code: NCT06305910

Phase 1, Recruiting

Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

for
Endometrial Cancer, Endometrioid Adenocarcinoma,
Location: Hartford CT, Commack NY, Rockville Centre NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT04291612

Recruiting

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

for
WHO Grade 3 Glioma, WHO Grade 4 Glioma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06444412

Phase 2, Recruiting

Pediatric Ovarian Tissue Banking - Operative Specimens From Females 0-18 Years of Age

for
Benign Cysts Ovarian, Cystectomy, Torsion,
Location: Chicago IL
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: Female

Age: 0 - 18

Code: NCT04118712

Recruiting

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Innovative Approach to Triage Oral Precancer

for
Oral Cancer, Oral Premalignant Lesion
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 19+

Code: NCT03202810

Recruiting

Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma

for
Refractory Multiple Myeloma
Location: Ottawa, Kingston, Hamilton, London, Vancouver, Victoria
Sponsor: Ontario Clinical Oncology Group (OCOG)

Sex: All

Age: 18+

Code: NCT06421675

Phase 2, Recruiting

Tirzepatide Weight Loss for MRD+ Early Breast Cancer

for
Breast Cancer, Breast Neoplasms, Breast Cancers
Location: Dallas TX
Sponsor: Baylor Research Institute

Sex: All

Age: 18+

Code: NCT06517212

Phase 2, Recruiting

Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Charlottesville VA, Ann Arbor MI, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT03523975

Phase 1, Phase 2, Recruiting

Phase I Study VG2025 as a Single Agent and in Combination Therapy With Nivolumab in Subjects With Advanced Malignant Solid Tumors

for
Solid Tumor
Location: Houston TX, Gilbert AZ
Sponsor: Virogin Biotech Canada Ltd

Sex: All

Age: 18+

Code: NCT05266612

Phase 1, Recruiting

Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer, Lung Cancer
Location: Los Angeles CA, Beverly Hills CA, Torrance CA
Sponsor: Karen Reckamp, MD, MS

Sex: All

Age: 18+

Code: NCT05401110

Phase 1, Recruiting

Parathyroid Tumor Clonal Status

for
Parathyroid Tumor, Primary Hyperparathyroidism,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: Female

Age: 18 - 70+

Code: NCT05997810

Recruiting

A Trial of Selinexor, Ruxolitinib and Methylprednisolone

for
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory
Location: West Hollywood CA
Sponsor: Oncotherapeutics

Sex: All

Age: 0+

Code: NCT06225310

Phase 1, Recruiting

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: San Diego CA, Los Angeles CA, Davis CA,
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06252675

Phase 2, Recruiting

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

for
HPV, Throat Cancer, Oropharyngeal Carcinoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05491512

Phase 2, Recruiting

Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma

for
Uveal Melanoma
Location: Washington D.C. DC, Pittsburgh PA, Columbus OH,
Sponsor: Diwakar Davar

Sex: All

Age: 18+

Code: NCT06070012

Phase 2, Recruiting

Circulating Tumor DNA in Soft Tissue Sarcoma

for
Soft Tissue Sarcoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03818412

Recruiting

Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer

for
Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18 - 50

Code: NCT04812912

Recruiting

A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer

for
Cancer Of Prostate, Prostate Neoplasms
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: Male

Age: 18 - 70+

Code: NCT04633252

Phase 1, Phase 2, Recruiting

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT00083512

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer