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Oncology Clinical Trials

Browse 9,232 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1

Oropharynx (OPX) Biomarker Trial

for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06356272

Recruiting

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

for
Solid Tumours, Sarcoma, HNSCC, Non Small Cell Lung Cancer,
Location: Houston TX, Beverly Hills CA, Santa Monica CA
Sponsor: Epkin

Sex: All

Age: 18+

Code: NCT06789172

Phase1, Recruiting

Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors

for
Metastatic Pancreatic Neuroendocrine Tumor
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06663072

Phase1, Recruiting

A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC)

for
Metastatic Renal Cell Carcinoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06835972

Phase1, Phase2, Recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

for
HPV-Associated Cervical Carcinoma, HPV-Related Carcinoma,
Location: New Brunswick NJ
Sponsor: Christian Hinrichs

Sex: All

Age: 18+

Code: NCT05639972

Phase1, Phase2, Recruiting

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Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

for
Gastroesophageal Junction, Gastroesophageal Adenocarcinoma,
Location: East Syracuse NY, Pittsburgh PA, Grand Rapids MI,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06445972

Phase1, Phase2, Recruiting

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

for
Colorectal Cancer, CRC
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT06728072

Phase2, Recruiting

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

for
Colorectal Adenocarcinoma, Stage I Colorectal Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04739072

Recruiting

Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.

for
Ovarian Cancer, Breast Cancer, Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05649072

Recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of BC3195 in Patients With Advanced or Metastatic Cancer

for
Advanced Cancer, Metastatic Solid Tumor
Location: Cleveland OH
Sponsor: Biocity Biopharmaceutics Co., Ltd.

Sex: All

Age: 18+

Code: NCT06548672

Phase1, Recruiting

Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation

for
Extensive Stage Lung Small Cell Carcinoma, Stage IV Lung Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06110572

Phase1, Phase2, Recruiting

Microwave Ablation of Primary and Secondary Lung Malignancies

for
Lung Neoplasms, Neoplasm Metastasis
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT04369872

Phase1, Phase2, Recruiting

Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes

for
Hereditary Colorectal Cancer Syndrome
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02863172

Recruiting

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

for
Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma,
Location: Boston MA, Chapel Hill NC, Columbus OH, Cincinnati OH,
Sponsor: Newave Pharmaceutical Inc

Sex: All

Age: 13+

Code: NCT04771572

Phase1, Recruiting

A Study of Ruxolitinib in Combination With Abemaciclib for the Treatment of Myelofibrosis

for
Myelofibrosis Due to and Following Polycythemia Vera
Location: Commack NY, Uniondale NY, East White Plains NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05714072

Phase1, Recruiting

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

for
Obesity, Malignant Neoplasm
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 13 - 30

Code: NCT04453072

Recruiting

Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC

for
Breast Cancer
Location: Dallas TX
Sponsor: Baylor Research Institute

Sex: Female

Age: 18+

Code: NCT04265872

Early_phase1, Recruiting

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for
Carcinoma, Hepatocellular, Cirrhosis
Location: Boston MA, West Haven CT, The Bronx NY, New York NY,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18 - 70+

Code: NCT05486572

Recruiting

Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia

for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03263572

Phase2, Recruiting

Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer

for
Prostate Cancer, Advanced Prostate Carcinoma
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT05396872

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer