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Oncology Clinical Trials

Browse 8,894 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

for
Colon Cancer Liver Metastasis, Colon Cancer,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04668872

Recruiting

Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy

for
Acute Myeloid Leukemia
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06279572

Recruiting

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05178472

Recruiting

Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors

for
Obesity, Smoking Cessation, Physical Inactivity
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT05687604

Recruiting

An Investigational Scan (Me-4FDG PET/CT) for the Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer

for
Lung Adenocarcinoma
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05558904

Phase1, Phase2, Recruiting

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A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

for
Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer,
Location: Austin TX, San Antonio TX, Scottsdale AZ
Sponsor: OncoResponse, Inc.

Sex: All

Age: 18+

Code: NCT05094804

Phase1, Phase2, Recruiting

Study of 2141-V11 in People With Non-muscle Invasive Bladder Cancer That Did Not Respond to Standard Treatment

for
Non-muscle Invasive Bladder Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05126472

Phase1, Phase2, Recruiting

Proton Therapy for Esophageal Cancer

for
Esophagus Cancer
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 18+

Code: NCT01684904

Recruiting

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK112 in Patients With Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Beverly Hills CA
Sponsor: Abbisko Therapeutics Co, Ltd

Sex: All

Age: 18+

Code: NCT06225804

Phase1, Recruiting

SNV4818 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, Philadelphia PA, Ottawa, Toronto,
Sponsor: Pikavation Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06736704

Phase1, Phase2, Recruiting

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

for
Oropharyngeal Cancer
Location: Sherbrooke, Berlin Corners VT, Burlington VT, Montreal,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT05451004

Phase3, Recruiting

EUS-CPN With and Without Bupivacaine

for
Pancreatic Cancer
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT04951804

Recruiting

Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies

for
Cancer, Ovarian, Chemotherapy Effect, Calorie Deficiency,
Location: Knoxville TN
Sponsor: L-Nutra Inc

Sex: Female

Age: 35 - 70

Code: NCT06376604

Recruiting

Cabozantinib for Patients With Recurrent or Progressive Meningioma

for
Meningioma
Location: New York NY, Miami FL, Nashville TN
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05425004

Phase2, Recruiting

Insomnia in Patients With Metastatic Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06472804

Recruiting

FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial

for
Castration-Sensitive Prostate Carcinoma,
Location: Chicago IL, Oak Brook IL, Warrenville IL, Geneva IL,
Sponsor: Northwestern University

Sex: Male

Age: 18+

Code: NCT06244004

Phase2, Recruiting

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

for
Metastatic Colorectal Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06149481

Phase1, Phase2, Recruiting

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

for
Adipocytic Neoplasm, Liposarcoma, Atypical Fibroxanthoma,
Location: Boston MA, Atlanta GA, Cincinnati OH, Chicago IL,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 30

Code: NCT06239272

Phase1, Phase2, Recruiting

REMASTer: REcurrent Brain Metastases After SRS Trial

for
Brain Metastases, Radiation Necrosis, Recurrent Tumor,
Location: Baltimore MD, Winston-Salem NC, Cleveland OH,
Sponsor: Monteris Medical

Sex: All

Age: 18+

Code: NCT05124912

Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for
Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer,
Location: Miami FL, Florence SC, Charleston SC, Cleveland OH,
Sponsor: Adela, Inc

Sex: All

Age: 40+

Code: NCT05366881

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer