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Oncology Clinical Trials

Browse 8,894 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer

for
Prostate Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male

Age: 18+

Code: NCT04167969

Phase1, Recruiting

PCORI-CER-1306-03385 Lung Cancer Screening Decision Aid Development and Testing

for
Health Knowledge, Attitudes, Practice
Location: Galveston TX, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 55 - 70+

Code: NCT02282969

Recruiting

Evaluating Safety and Efficacy of Verity-BCG in BCG-naïve Patients With Intermediate and High-risk Non-muscle Invasive Bladder (NMIBC)

for
Bladder Cancer, Bladder Cancer Recurrent, Neoplasm Recurrence,
Location: Kingston, Toronto, Vancouver
Sponsor: Verity Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT05037279

Phase3, Recruiting

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

for
Liver Transplant Surgery, Colorectal Cancer Metastatic,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT06698146

Recruiting

Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys

for
HIV Infections
Location: San Clemente CA
Sponsor: Center for Innovative Public Health Research

Sex: Male

Age: 13 - 22

Code: NCT06230367

Recruiting

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CSF Analysis in EGFR Mutant Non-Small Cell Lung Cancer with Leptomeningeal Disease

for
EGFR Activating Mutation, Leptomeningeal Metastasis,
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT05257967

Recruiting

Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic

for
COVID-19 Infection, Melanoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT04474301

Recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL)

for
Renal AL Amyloidosis
Location: Detroit MI
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 18+

Code: NCT06420167

Phase2, Recruiting

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

for
Non-small Cell Lung Cancer
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT04332367

Phase2, Recruiting

Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma

for
Congenital Hyperinsulinism, Insulinoma
Location: Fort Worth TX
Sponsor: Cook Children's Health Care System

Sex: All

Age: 0 - 18

Code: NCT02021604

Phase1, Recruiting

Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant

for
Acute Myeloid Leukemia
Location: Miami FL, Indianapolis IN, Houston TX
Sponsor: Huda Salman

Sex: All

Age: 12+

Code: NCT06197672

Phase1, Recruiting

The MARVIN Chatbots to Provide Information for Different Health Conditions

for
HIV Infections, Breast Cancer, Pediatric Emergency Medicine
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 14+

Code: NCT05789901

Recruiting

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

for
Glioblastoma, IDH-wildtype, Glioblastoma,
Location: Providence RI, New York NY, Durham NC, Cleveland OH,
Sponsor: Orbus Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05879367

Phase1, Recruiting

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

for
Advanced Melanoma
Location: Bethesda MD, Hialeah FL, Toronto, Pittsburgh PA,
Sponsor: Eikon Therapeutics

Sex: All

Age: 18+

Code: NCT06697301

Phase2, Phase3, Recruiting

Cardiac Rehabilitation for Breast Cancer Survivors

for
Breast Cancer, Cardiovascular Diseases
Location: Toronto
Sponsor: Women's College Hospital

Sex: Female

Age: 50+

Code: NCT06251401

Recruiting

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Scarborough ME, Providence RI, New Haven CT, Mineola NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06824467

Phase3, Recruiting

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

for
Primary T-cell Immunodeficiency Disorders,
Location: Bethesda MD, Minneapolis MN
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 4 - 70+

Code: NCT02579967

Phase2, Recruiting

Intra-Operative Radiation Registry

for
Breast Cancer
Location: The Bronx NY
Sponsor: Albert Einstein College of Medicine

Sex: Female

Age: 18+

Code: NCT04994067

Recruiting

Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era

for
Prostate Cancer Recurrent, Prostate Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18+

Code: NCT06508567

Recruiting

Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC)

for
Rectal Cancer
Location: Tampa FL
Sponsor: University of South Florida

Sex: All

Age: 18 - 70+

Code: NCT06380101

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer