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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

for
Anatomic Stage 0 Breast Cancer AJCC v8,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 40+

Code: NCT04959474

Recruiting

Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer

for
Advanced or Metastatic CRC
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT06833866

Phase 1, Recruiting

Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis

for
Hemoptysis, Haemoptysis, Lung Disease, Pneumonia, Tuberculosis,
Location: Sherbrooke
Sponsor: Université de Sherbrooke

Sex: All

Age: 18+

Code: NCT02913365

Recruiting

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

for
Bone Sarcoma, Osteosarcoma, Chondrosarcoma, Ewing's Sarcoma,
Location: Uniondale NY, Harrison NY, New York NY, Middletown NJ,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 4+

Code: NCT03442465

Recruiting

Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

for
PSMA PET-Positive Castration-Resistant Prostate Cancer
Location: Boston MA, New York NY, Durham NC, Cleveland OH,
Sponsor: Convergent Therapeutics

Sex: Male

Age: 18+

Code: NCT06549465

Phase 2, Recruiting

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Acute Concussion and Melatonin

for
Concussion, Mild, Concussion, Brain, Pediatric ALL
Location: Washington DC
Sponsor: Children's National Research Institute

Sex: All

Age: 12 - 18

Code: NCT04731974

Phase 2, Recruiting

Evaluation of IRDye800CW-nimotuzumab in Lung Cancer Surgery

for
Lung Cancer
Location: Saskatoon
Sponsor: University of Saskatchewan

Sex: All

Age: 18 - 70+

Code: NCT04459065

Phase 1, Phase 2, Recruiting

Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

for
Pancreatic Adenocarcinoma
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT03080974

Phase 2, Recruiting

A Study of Patients With Relapsed/Refractory Mantle Cell Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting

for
Mantle Cell Lymphoma (MCL)
Location: Milwaukee WI
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06788652

Recruiting

Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation Program

for
Pancreatic Cancer, Liver Cancer, Bile Duct Cancer,
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18 - 70+

Code: NCT03475966

Recruiting

Single Pre-Operative Radiation Therapy - With Delayed or No Surgery (SPORT-DNS)

for
Breast Cancer
Location: Montreal
Sponsor: Maisonneuve-Rosemont Hospital

Sex: Female

Age: 50+

Code: NCT05217966

Recruiting

Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples

for
Papillary Thyroid Cancer
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT06133374

Recruiting

Effect of a Nutritional Supplement on H&N Cancer Patients

for
Head and Neck Cancer
Location: Hines IL
Sponsor: Edward Hines Jr. VA Hospital

Sex: All

Age: 30 - 70+

Code: NCT00296452

Recruiting

IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures

for
Cancer Metastatic, Trauma, Pathologic Fracture
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 21+

Code: NCT04842266

Recruiting

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

for
Prostate Cancer
Location: Boston MA, Ottawa, Toronto, London, Ann Arbor MI,
Sponsor: University of British Columbia

Sex: Male

Age: 18+

Code: NCT04812366

Phase 2, Recruiting

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

for
Head and Neck Squamous Cell Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06597565

Phase 2, Recruiting

Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer

for
Esophageal Squamous Cell Carcinoma
Location: Montreal
Sponsor: Karolinska University Hospital

Sex: All

Age: 18 - 70+

Code: NCT04460352

Phase 3, Recruiting

Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients

for
Multiple Endocrine Neoplasia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT03048266

Recruiting

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

for
NSCLC (Non-small Cell Lung Cancer), Solid Tumor
Location: Fairfax VA
Sponsor: Yuhan Corporation

Sex: All

Age: 18+

Code: NCT06616766

Phase 1, Phase 2, Recruiting

Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics

for
Breast Cancer, Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05694559

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer