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Oncology Clinical Trials

Browse 9,272 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

for
Head and Neck Squamous Cell Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06597565

Phase 2, Recruiting

FAZA PETMRI Gastro-Oesophageal Study

for
Metastasized Gastro-Oesophageal Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04560036

Recruiting

Strategic Targeting for Optimal Prevention of Cancer

for
Early Detection of Cancer
Location: Prosper TX
Sponsor: ClinLogic LLC

Sex: All

Age: 65+

Code: NCT03897374

Recruiting

Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients

for
Multiple Endocrine Neoplasia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT03048266

Recruiting

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

for
NSCLC (Non-small Cell Lung Cancer), Solid Tumor
Location: Fairfax VA
Sponsor: Yuhan Corporation

Sex: All

Age: 18+

Code: NCT06616766

Phase 1, Phase 2, Recruiting

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Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer

for
Pancreatic Cancer
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 18+

Code: NCT06205849

Phase 1, Recruiting

68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas

for
Soft Tissue Sarcoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06500065

Recruiting

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

for
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: Charlotte NC, Memphis TN, Tulsa OK
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06533748

Phase 2, Recruiting

Brain Slice Explants to Predict Drug Response in Brain Tumors

for
Central Nervous System Tumor
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 0+

Code: NCT05978557

Recruiting

Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position

for
Breast Cancer, Radiation Dermatitis
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06915857

Phase 3, Recruiting

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions

for
Brain Metastases, Adult, Neurocognitive Function, Cancer,
Location: San Diego CA
Sponsor: Jona Hattangadi-Gluth

Sex: All

Age: 18+

Code: NCT04343157

Phase 2, Recruiting

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for
Neoplasms
Location: The Bronx NY, New York NY, East Brunswick NJ,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06150157

Phase 1, Recruiting

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

for
Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer,
Location: Pittsburgh PA
Sponsor: Dan Zandberg

Sex: All

Age: 18+

Code: NCT04114136

Phase 2, Recruiting

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

for
Advanced Solid Tumor, Cutaneous T-cell Lymphoma (CTCL)
Location: Huntersville NC
Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT05569057

Phase 1, Recruiting

Investigations of Reproductive Cancers in Women

for
Uterine Cancer
Location: New York NY, Orlando FL, Akron OH, Columbus OH,
Sponsor: PinkDx, Inc.

Sex: Female

Age: 45 - 70+

Code: NCT06527157

Recruiting

Connecting Families

for
Poverty, Primary Care, Intervention
Location: Kingston
Sponsor: Queen's University

Sex: All

Age: 0 - 3

Code: NCT05091957

Recruiting

CKD Specific Telemonitoring Platform to Minimize Adverse Outcomes in High Risk CKD Patients

for
Chronic Kidney Disease Stage 5, End Stage Renal Disease
Location: Scarborough Village, London, Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 18+

Code: NCT05726526

Recruiting

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

for
Solid Tumor, Adult, Carcinoma, Ovarian Epithelial,
Location: Silver Spring MD, Detroit MI, Houston TX, Dallas TX
Sponsor: Bio-Path Holdings, Inc.

Sex: All

Age: 18+

Code: NCT04196257

Phase 1, Recruiting

Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Columbus OH
Sponsor: Margaret Gatti-Mays

Sex: All

Age: 18+

Code: NCT06026657

Phase 1, Phase 2, Recruiting

PSMA PET Response Guided SabR in High Risk Pca

for
Prostate Adenocarcinoma
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: Male

Age: 18 - 70+

Code: NCT06044857

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer