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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for
Recurrent Ovarian High Grade Serous Adenocarcinoma,
Location: Philadelphia PA, Charlottesville VA, Winston-Salem NC,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT04633239

Phase1, Recruiting

Increasing Equity in Lung Cancer Screening

for
Lung Cancer
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 50 - 70+

Code: NCT06360822

Recruiting

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

for
Advanced or Metastatic Solid Tumors, Non Small Cell Lung Cancer,
Location: Boston MA, New Haven CT, Fairfax VA, Nashville TN,
Sponsor: Incendia Therapeutics

Sex: All

Age: 18+

Code: NCT05753722

Phase1, Recruiting

Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain

for
Post-surgical Pain, Pain, Chronic, Intercostal Pain,
Location: Hamilton
Sponsor: McMaster University

Sex: Female

Age: 18+

Code: NCT03421522

Recruiting

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

for
Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06268665

Phase2, Recruiting

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Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

for
Lung Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT00898313

Recruiting

UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning

for
Prostate Cancer
Location: Jacksonville FL
Sponsor: University of Florida

Sex: Male

Age: 18 - 70+

Code: NCT06465966

Recruiting

Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma

for
Sarcoma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0+

Code: NCT00579566

Recruiting

Profile Related Evidence to Determine Individualized Cancer Therapy (PREDICT) Program in Advanced Cancer Patients

for
Advanced Cancers
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT02160366

Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

for
Advanced Solid Tumor, Metastatic Cancer, Cutaneous Melanoma,
Location: Morristown NJ, Miami FL, Huntersville NC,
Sponsor: Aulos Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05267626

Phase1, Phase2, Recruiting

Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Congestive Heart Failure Receiving Therapy for Breast Cancer

for
Breast Carcinoma
Location: Boston MA
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT02610426

Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for
Metastatic Breast Cancer
Location: Boston MA, New York NY, New Brunswick NJ, Montreal,
Sponsor: LeonaBio

Sex: All

Age: 18+

Code: NCT05696626

Phase3, Recruiting

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for
mCRPC (Metastatic Castration-resistant Prostate Cancer),
Location: New York NY, Baltimore MD, Fairfax VA, Durham NC,
Sponsor: Pathos AI, Inc.

Sex: Male

Age: 18+

Code: NCT06785636

Phase1, Phase2, Recruiting

Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies

for
Sarcoma, Gastrointestinal Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05743426

Recruiting

MRI/Ultrasound Fusion Guided Laser Ablation of Prostate Cancer

for
Neoplasms Prostate, Cancer of the Prostate
Location: Miami Lakes FL
Sponsor: Urological Research Network, LLC

Sex: Male

Age: 50+

Code: NCT05241236

Recruiting

The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families

for
Parent Child Relationship, Child Social-Emotional Development,
Location: Raleigh NC
Sponsor: University of Washington

Sex: Female

Age: 18+

Code: NCT06740266

Recruiting

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

for
Medulloblastoma
Location: Orlando FL, Tampa FL, Ann Arbor MI, Memphis TN,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 4

Code: NCT05535166

Phase2, Recruiting

A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies

for
NSCLC
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Ellipses Pharma

Sex: All

Age: 18+

Code: NCT05443126

Phase1, Phase2, Recruiting

Vit D3 and Omega 3 in Chemo Induced Neuropathy

for
Cancer, Neuropathy
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18+

Code: NCT02294149

Phase3, Recruiting

Transrectal Ultrasound Robot-Assisted Prostate Biopsy

for
Prostate Cancer
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: Male

Age: 45 - 70+

Code: NCT02871726

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer