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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

for
Prostate Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: Male

Age: 18+

Code: NCT04692675

Recruiting

A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer

for
Low-Grade Serous Ovarian Cancer
Location: Commack NY, Uniondale NY, East White Plains NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT06394804

Phase 2, Recruiting

Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

for
Childhood Cancer, Muscle Weakness
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 18+

Code: NCT06819475

Recruiting

Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma

for
Relapsed Neuroblastoma, Refractory Neuroblastoma,
Location: Boston MA
Sponsor: Roberto Chiarle

Sex: All

Age: 1 - 29

Code: NCT06803875

Phase 1, Phase 2, Recruiting

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma
Location: Boston MA, Montreal, Philadelphia PA,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 0 - 21

Code: NCT04655404

Early Phase 1, Recruiting

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Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies

for
Hematologic Malignancy, Large B-cell Lymphoma,
Location: Los Angeles CA
Sponsor: Joshua Sasine, MD, PhD

Sex: All

Age: 18 - 70+

Code: NCT05887167

Phase 1, Recruiting

EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

for
Lung Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06105801

Recruiting

Study of Fluphenazine in Relapsed or Relapsed-and-Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Philadelphia PA, San Antonio TX
Sponsor: Immune Control

Sex: All

Age: 18+

Code: NCT00821301

Phase 1, Recruiting

A Study Evaluating MM-310 in Patients With Solid Tumors

for
Solid Tumors, Urothelial Carcinoma, Gastric Carcinoma,
Location: Durham NC, Buffalo NY, Rochester MN, Scottsdale AZ,
Sponsor: Merrimack Pharmaceuticals

Sex: All

Age: 18+

Code: NCT03076372

Phase 1, Recruiting

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

for
EGFR Gene Mutation, Glioblastoma,
Location: San Francisco CA
Sponsor: Hideho Okada, MD, PhD

Sex: All

Age: 18+

Code: NCT06186401

Phase 1, Recruiting

A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery

for
Breast Cancer
Location: New York NY, Montvale NJ
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT05130801

Phase 1, Phase 2, Recruiting

Collecting and Storing Tissue Samples From Women With or Without Breast Cancer

for
Breast Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: Female

Age: 18+

Code: NCT00899301

Recruiting

Chemotherapy Effect on Brain Structure, Neurophysiology and Psychomotor Behavior in Breast Cancer Patients

for
Breast Cancer
Location: West Orange NJ
Sponsor: Kessler Foundation

Sex: Female

Age: 20 - 70

Code: NCT02896504

Recruiting

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

for
Prostatic Neoplasms, Castration-Resistant
Location: New York NY, Grand Rapids MI, River Ridge LA,
Sponsor: Clarity Pharmaceuticals Ltd

Sex: Male

Age: 18+

Code: NCT04868604

Phase 1, Phase 2, Recruiting

Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

for
Prostate Cancer
Location: Hampton VA, Warrenville IL, Oklahoma City OK,
Sponsor: Proton Collaborative Group

Sex: Male

Age: 18+

Code: NCT01492972

Phase 3, Recruiting

Assessment of Geriatric Evaluations Impact on New AML Guidance

for
AML, Adult
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 50+

Code: NCT05909501

Recruiting

ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services

for
HIV, Cervical Cancer
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: Female

Age: 25 - 64

Code: NCT06128304

Recruiting

Tranexamic Acid in Nasal Mohs Reconstruction

for
Postoperative Bleeding, Skin Cancer Face
Location: Nashville TN
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 18+

Code: NCT06057675

Phase 2, Recruiting

Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)

for
Metastatic Breast Cancer, Lobular Breast Carcinoma
Location: Philadelphia PA, Houston TX, San Diego CA,
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT05964504

Recruiting

CC-486 and Venetoclax for Acute Myeloid Leukemia

for
AML
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT05287568

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer