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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With Glioblastoma

for
Glioblastoma Multiforme
Location: Montreal, Calgary
Sponsor: Bassam Abdulkarim

Sex: All

Age: 18 - 70

Code: NCT02928575

Phase 2, Recruiting

A Prospective Observational Study to Evaluate Acute Kidney Injury Biomarkers In Patients Receiving First Cycle of Cisplatin Chemotherapy for Head and Neck Cancers

for
Head and Neck Cancer
Location: Boston MA, Houston TX
Sponsor: Foundation for the National Institutes of Health

Sex: All

Age: 18+

Code: NCT01936376

Recruiting

A Study of Surgical Techniques During Cystectomy

for
Bladder Cancer
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 21+

Code: NCT06703476

Phase 3, Recruiting

Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host

for
Colorectal Neoplasms, Colorectal Cancer, Breast Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT02732860

Recruiting

A Phase I-II Study Investigating the All-Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)

for
Acute Myeloid Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12+

Code: NCT05360160

Phase 1, Phase 2, Recruiting

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A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)

for
Hairy Cell Leukemia
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06561360

Phase 2, Recruiting

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

for
Pheochromocytoma, Paraganglioma, Neuroendocrine Tumors,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03206060

Phase 2, Recruiting

A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients

for
Melanoma
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT01638676

Phase 1, Phase 2, Recruiting

Determining the Link Between Dietary Patterns, Fecal Microbiome and Response to Neoadjuvant Chemotherapy

for
Borderline Resectable Pancreatic Ductal Adenocarcinoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06595160

Recruiting

Study of Skin Tumors in Tuberous Sclerosis

for
Tuberous Sclerosis
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT00001975

Recruiting

Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)

for
Ovarian Cancer
Location: New York NY, Newport News VA, Baltimore MD, York PA,
Sponsor: NX Development Corp

Sex: Female

Age: 18+

Code: NCT05804370

Phase 3, Recruiting

Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers

for
Cholangiocarcinoma, Bile Duct Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04645160

Phase 1, Phase 2, Recruiting

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

for
Acute Myeloid Leukemia,
Location: Boston MA, Cleveland OH, Houston TX, Portland OR
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03471260

Phase 1, Phase 2, Recruiting

NIDCD Otolaryngology Clinical Protocol Biospecimen Bank

for
Hearing Loss, Head and Neck Neoplasms, Hearing Disorders,
Location: Bethesda MD
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)

Sex: All

Age: 3 - 70+

Code: NCT06303180

Recruiting

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma
Location: New Hyde Park NY, Tampa FL, Chicago IL, Los Angeles CA
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06121180

Phase 2, Recruiting

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for
Gastric Cancer
Location: New York NY, Grand Rapids MI, Baton Rouge LA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05702229

Phase 2, Recruiting

Molecular Profiling After Neoadjuvant Chemotherapy for Triple-negative Breast Cancer

for
Triple-negative Breast Cancer
Location: El Paso TX
Sponsor: Texas Tech University Health Sciences Center, El Paso

Sex: Female

Age: 18 - 70+

Code: NCT04362462

Recruiting

Cardioprotection in AML

for
AML, Acute Myeloid Leukemia
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT04977180

Phase 2, Recruiting

Postoperative Pain Control With Lipossomic Extended Release Bupivacaine

for
Pain, Postoperative, Lung Cancer
Location: Memphis TN
Sponsor: University of Tennessee

Sex: All

Age: 18+

Code: NCT03560362

Phase 1, Phase 2, Recruiting

Improving Genetic Counseling for BRCA+ Mothers

for
Breast Cancer
Location: Washington DC
Sponsor: Georgetown University

Sex: Female

Age: 18+

Code: NCT04258280

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer