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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

for
Leukemia
Location: Boston MA, Memphis TN, Houston TX, Seattle WA
Sponsor: Dutch Childhood Oncology Group

Sex: All

Age: 0 - 1

Code: NCT00550992

Recruiting

The Ohio State University (OSU) SCREEN Community Program

for
Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 0+

Code: NCT06666192

Recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252

for
Recurrent High Grade Glioma
Location: New York NY, Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06126744

Phase1, Recruiting

A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Lake Success NY, New York NY, Miami FL, Pittsburgh PA,
Sponsor: Syncromune, Inc.

Sex: Male

Age: 18+

Code: NCT06533644

Phase2, Recruiting

Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

for
Schwannomatosis, Schwannomas, Pain, Chronic
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05684692

Phase2, Recruiting

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Safety Study of CAT-8015 Immunoxin in Patients With NHL With Advance Disease

for
Leukemia, Non-Hodgkin's Lymphoma, NHL
Location: Bethesda MD, Beverly Hills CA
Sponsor: Cambridge Antibody Technology

Sex: All

Age: 18+

Code: NCT00515892

Phase1, Recruiting

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

for
Cancer, Cancer Gene Mutation, PAN Gene Mutation,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06008392

Recruiting

Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes

for
Melanoma
Location: Maywood IL
Sponsor: Loyola University

Sex: All

Age: 18 - 70+

Code: NCT02870244

Phase1, Recruiting

AnovaOS Network Powered Patient Registry

for
Infectious Disease, Neoplasms,
Location: Arlington Heights IL
Sponsor: Anova Enterprises, Inc

Sex: All

Age: 18+

Code: NCT05013944

Recruiting

Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?

for
Sarcoma, Bone Metastases, Proximal Femur Replacement
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 16 - 70+

Code: NCT03261544

Recruiting

Mindfulness in Endometrial and Cervical Cancer

for
Gynecologic Cancer, Endometrial Cancer, Cervical Cancer,
Location: St Louis MO
Sponsor: St. Louis University

Sex: Female

Age: 18 - 70+

Code: NCT04512144

Recruiting

Everglade Stem, World Cup and World Liner Post Market Clinical Follow-up

for
Hip Disease
Location: Cleveland OH
Sponsor: Signature Orthopaedics

Sex: All

Age: 18 - 70+

Code: NCT06153940

Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

for
Glioblastoma, Glioblastoma Multiforme, Glioma, Malignant, GBM,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT05271240

Phase3, Recruiting

Tumor Grade Determines PD-1/PDL-1 Expression

for
Endometrial Cancer, Ovarian Cancer
Location: Jersey City NJ
Sponsor: RWJ Barnabas Health at Jersey City Medical Center

Sex: Female

Age: 0+

Code: NCT04528940

Recruiting

Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma

for
Melanoma, Melanoma Stage III, Melanoma (Skin),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06771544

Phase2, Recruiting

BHB & CAR-T for Lymphomas

for
Large B-cell Lymphoma
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06610344

Recruiting

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for
Prostate Cancer, Oligometastasis, Oligorecurrence,
Location: Boston MA, Philadelphia PA, Baltimore MD,
Sponsor: VA Office of Research and Development

Sex: Male

Age: 18+

Code: NCT04787744

Phase2, Phase3, Recruiting

NSAID Use After Robotic Partial Nephrectomy

for
Kidney Cancer, Renal Cancer, Renal Neoplasm
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18 - 70+

Code: NCT05842044

Phase2, Recruiting

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

for
HER2-negative Breast Cancer Patients With Brain Metastases
Location: Stony Brook NY, Baltimore MD, Augusta GA, Chicago IL,
Sponsor: Biostar Pharma, Inc.

Sex: All

Age: 18+

Code: NCT06764940

Phase2, Recruiting

In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

for
Pheochromocytoma, Paraganglioma
Location: Philadelphia PA
Sponsor: Heather Wachtel

Sex: All

Age: 18+

Code: NCT05636540

Early_phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer