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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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New

Whole Body Metabolic Activity as a Reflection of Tumor Metabolic Dysregulation and a Predictor of Treatment Response in Ovarian Cancer

for
Epithelial Ovarian Cancer
Location: Knoxville TN
Sponsor: University of Tennessee Graduate School of Medicine

Sex: Female

Age: 18+

Code: NCT07764133

Recruiting
New

Luminal Bladder Cancer Effective Response to Neoadjuvant Chemotherapy (LUMBER-NAC)

for
Bladder Cancer
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT07762586

Phase2, Recruiting
New

Evaluating the Impact of CONNECT in a Multilingual Population

for
Smoking Cessation,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 50 - 70+

Code: NCT07111936

Recruiting
New

M-2018-334 in Hematological Malignancies

for
Hematological Malignancies
Location: Duarte CA
Sponsor: Miltenyi Biomedicine GmbH

Sex: All

Age: 18 - 70+

Code: NCT06225050

Recruiting
New

Effectiveness of an eHealth Intervention for Uptake of Cervical Cancer Screening in Hispanic Women

for
Cervical Cancer Screening
Location: Tallahassee FL
Sponsor: Florida A&M University

Sex: Female

Age: 21 - 65

Code: NCT06741241

Recruiting

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New

Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain Metastases

for
Breast Cancer, Breast Carcinoma, Cancer of the Breast,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT07619534

Recruiting
New

A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer

for
Hormone Receptor Positive Early Breast Cancer
Location: Margate FL, Beverly Hills CA
Sponsor: Rovi Pharmaceuticals Laboratories

Sex: Female

Age: 18 - 70+

Code: NCT07401381

Phase1, Recruiting
New

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

for
Selected Advanced Solid Tumors, Colorectal Cancer (CRC),
Location: Glen Burnie MD
Sponsor: SK Life Science, Inc.

Sex: All

Age: 18+

Code: NCT07812805

Phase1, Recruiting
New

A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors
Location: Lake Success NY, Fairfax VA
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07730021

Phase1, Phase2, Recruiting
New

A Study of MX006 in Patients With Advanced and/or Metastatic Tumors Known to Express B7-H3

for
Advanced and/or Metastatic Solid Tumors Known to Express B7-H3
Location: Fairfax VA, Sarasota FL, Houston TX, San Antonio TX
Sponsor: Myricx Pharma Limited

Sex: All

Age: 18+

Code: NCT07807241

Phase1, Recruiting
New

Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New York NY, Houston TX
Sponsor: OncoC4, Inc.

Sex: All

Age: 18+

Code: NCT07408258

Phase1, Recruiting
New

Low Dose Naltrexone (LDN) for Management of Fatigue in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)

for
Metastatic Prostate Cancer
Location: Little Rock AR
Sponsor: University of Arkansas

Sex: Male

Age: 18+

Code: NCT07224009

Phase2, Recruiting
New

Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence

for
Prostate Cancer
Location: Portland OR
Sponsor: Blue Earth Diagnostics

Sex: Male

Age: 18+

Code: NCT07569926

Recruiting
New

EORTC Metastatic Breast Cancer Module Development

for
Metastatic Beast Cancer
Location: Toronto
Sponsor: University of Leeds

Sex: Female

Age: 18+

Code: NCT07806266

Recruiting
New

Safety of Perioperative Anticoagulation Management in People With Active Cancer Undergoing Cancer-Related Surgery or Procedures (ACE-HIGH Study)

for
Thrombosis, Cancer, Thrombosis, Deep Vein,
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT07372716

Recruiting
New

NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies

for
Metastatic Malignant Neoplasm
Location: The Bronx NY, Baltimore MD, Fairfax VA, Nashville TN,
Sponsor: NextPoint Therapeutics, Inc.

Sex: All

Age: 19+

Code: NCT07563829

Phase1, Recruiting
New

Community Enhanced Virtual Informed Consent

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07805083

Recruiting
New

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

for
Clear Cell Renal Cell Carcinoma,
Location: New Haven CT
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07516366

Phase2, Recruiting
New

A Study of Armored CAR T Cells in People With Cancer

for
Neuroendocrine Cancer, Small Cell Lung Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07783477

Phase1, Recruiting
New

Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients

for
Head and Neck Disorder, Head and Neck Cancer
Location: Pittsburgh PA
Sponsor: Matthew Spector

Sex: All

Age: 18+

Code: NCT07631650

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer