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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

CanScan; Community-based Registry to Assess, Address and advaNce SCreening for cANcer Prevention and Management

for
Cancer Risk
Location: Totowa NJ
Sponsor: Hackensack Meridian Health

Sex: All

Age: 18+

Code: NCT06804395

Recruiting
Active & Responsive

Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors

for
Healthy Volunteers, Pancreatic Ductal Adenocarcinoma,
Location: The Bronx NY
Sponsor: Radiopharm Theranostics, Ltd

Sex: All

Age: 18+

Code: NCT05799274

Phase1, Recruiting
Active & Responsive

Increasing Germline Genetic Testing for Patients With Cancer

for
Hereditary Pancreatic Cancer, Conditions or Focus of Study,
Location: Danville PA, Durham NC, Salisbury NC, Orlando FL,
Sponsor: Josh Peterson

Sex: All

Age: 0+

Code: NCT07307664

Recruiting
Active & Responsive

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

for
Ovarian Cancer
Location: Providence RI, Morristown NJ, Rochester NY, Miami FL,
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 50 - 70+

Code: NCT00539162

Recruiting
Active & Responsive

Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

for
Breast Cancer Screening, Breast Carcinoma in Situ,
Location: New York NY, Miami FL, Birmingham AL, Chicago IL,
Sponsor: University of California, San Francisco

Sex: Female

Age: 30 - 70+

Code: NCT02620852

Recruiting

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Active & Responsive

Caris Biorepository Research Protocol

for
Cancer, Early Detection of Cancer, Minimal Residual Disease
Location: Ridge NY, Sparta NJ, Potsdam NY, Baltimore MD,
Sponsor: Caris Science, Inc.

Sex: All

Age: 18+

Code: NCT01499394

Recruiting
Active & Responsive

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: East Stroudsburg PA, Wilmington DE, Bethlehem PA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07091617

Recruiting
Active & ResponsiveNew

Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: Tampa FL
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07805954

Phase3, Recruiting
Active & ResponsiveNew

Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors

for
Prostate Cancer
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: Male

Age: 18+

Code: NCT07226713

Phase2, Recruiting
Active & ResponsiveNew

A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information

for
Clinical Stage 0 Cutaneous Melanoma AJCC v8,
Location: Philadelphia PA, Pittsburgh PA, Knoxville TN,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT07621614

Recruiting
Active & ResponsiveNew

Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma

for
Locally Advanced Ampulla of Vater Carcinoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07780838

Phase2, Recruiting
Active & ResponsiveNew

Intratumoral MMR Vaccine Injection in Borderline Resectable/Unresectable Pancreatic Cancer

for
Borderline Resectable/Unresectable Pancreatic Cancer,
Location: Little Rock AR
Sponsor: University of Arkansas

Sex: All

Age: 18+

Code: NCT07539155

Phase1, Phase2, Recruiting
Active & ResponsiveNew

Effect of Meal Timing During Adjuvant Treatment for Cancer

for
Cancer
Location: Los Angeles CA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07524218

Recruiting
Active & ResponsiveNew

Regorafenib (Reg) and Lorigerlimab (Lor), RELO Regimen, in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy [ReLOAD Trial]

for
Colorectal Cancer, Regorafenib, High Risk Patients
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07071961

Phase2, Recruiting
Active & ResponsiveNew

Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial

for
Metastatic Castration-Resistant Prostate Adenocarcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: Male

Age: 18+

Code: NCT07698535

Phase2, Recruiting
Active & ResponsiveNew

e-Health Psychosocial Stress and Symptom Management (ePSMI) for Pancreatic Cancer Patients

for
Pancreatic Cancer
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT06893276

Recruiting
Active & ResponsiveNew

A Study to Identify Breast Cancer (IDBC)

for
Breast Cancer Female
Location: Calgary
Sponsor: Syantra Inc.

Sex: Female

Age: 30 - 70+

Code: NCT04495244

Recruiting
Active & ResponsiveNew

A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

for
Hepatocellular Carcinoma (HCC), Metastatic Uveal Melanoma,
Location: Scottsdale AZ
Sponsor: VM Discovery, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07636785

Phase1, Phase2, Recruiting
Active & ResponsiveNew

Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

for
Colorectal Cancer, Metastatic Colorectal Cancer (CRC)
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT07759921

Recruiting
Active & ResponsiveNew

Patient Navigation for HER2+ Metastatic Breast Cancer Patients Treated With Tucatinib

for
HER2+ Metastatic Breast Cancer (MBC)
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 18+

Code: NCT06983691

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer