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Oncology Clinical Trials

Browse 8,905 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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Active & ResponsiveNew

First in Human Study of SNV1521 With a RAS Inhibitor for People With Advanced Pancreatic Cancer

for
Pancreatic Cancer, Pancreatic Acinar Carcinoma
Location: Houston TX
Sponsor: ParVation Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07756281

Phase 1, Recruiting
Active & ResponsiveNew

Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic

for
Head & Neck Squamous Cell Carcinoma, Non-Small Cell Lung Cancer,
Location: Fairfax VA, Orlando FL, Irving TX
Sponsor: Sutro Biopharma, Inc.

Sex: All

Age: 18+

Code: NCT07807345

Phase 1, Recruiting
Active & ResponsiveNew

Single FrAction Interstitial BreaSt BracHytherApy

for
Breast Cancer
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: Female

Age: 40 - 70+

Code: NCT07654257

Phase 2, Recruiting
Active & ResponsiveNew

BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies

for
Leptomeningeal Metastasis, Breast Cancer, Lung Cancer (NSCLC)
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT07789912

Recruiting
Active & ResponsiveNew

EXercise-induced PhysioLogical Adaptations In Neurological Disorders

for
Epilepsy, Functional Neurological Disorder,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT07883720

Recruiting

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Active & ResponsiveNew

Histotripsy in Biliary Tract Cancer

for
Biliary Track Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07853690

Recruiting
Active & ResponsiveNew

A Study to Evaluate ATX-898 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Fairfax VA, Houston TX, Fort Worth TX, San Antonio TX,
Sponsor: Antares Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT07767474

Phase 1, Phase 2, Recruiting
Active & ResponsiveNew

This is a Phase 1/1b Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors

for
Colorectal Cancer, Advanced/Metastatic Solid Tumor,
Location: Scottsdale AZ
Sponsor: LTZ Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07878988

Phase 1, Recruiting
Active & ResponsiveNew

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

for
Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 12+

Code: NCT07430202

Phase 1, Recruiting
Active & ResponsiveNew

Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently Diagnosed Cancer

for
Cancer
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07811258

Recruiting
Active & Responsive

RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

for
Adenocarcinoma of Lung, Lung Cancer
Location: Duluth MN, Virginia MN, Hibbing MN, Sandstone MN,
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT04105270

Phase 2, Recruiting
Active & Responsive

ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial

for
Endometrial Cancer
Location: Toronto, Edmonton
Sponsor: University of Alberta

Sex: Female

Age: 18+

Code: NCT06038032

Recruiting
Active & Responsive

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

for
Advanced Solid Tumor
Location: East Providence RI, Charleston SC, Huntersville NC,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06750185

Phase 1, Phase 2, Recruiting
Active & Responsive

Evaluating the Implementation of a Comprehensive Multilevel Virtual Oncology Program Among Veterans Diagnosed With Lung, Colorectal, Prostate, and Breast Cancers in the US Department of Veterans Affairs

for
Lung Cancer Diagnosis, Colorectal Cancer (Diagnosis),
Location: Jamaica NY, New York NY, Brooklyn NY, Staten Island NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06559059

Recruiting
Active & Responsive

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

for
Lung Cancer, Small-cell Lung Cancer, Non Small Cell Lung Cancer
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT05800587

Phase 2, Recruiting
Active & Responsive

Pre-Operative Window of ET to Inform RT Decisions (POWER II)

for
Breast Cancer Female
Location: New Haven CT, Newport News VA, Richmond VA, Fairfax VA,
Sponsor: University of Virginia

Sex: Female

Age: 65+

Code: NCT06507618

Phase 3, Recruiting
Active & Responsive

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

for
Tumors Metastatic to Brain
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT01891318

Phase 1, Phase 2, Recruiting
Active & Responsive

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

for
Metastatic Breast Cancer
Location: Brewer ME, Augusta ME, Weymouth MA, Boston MA,
Sponsor: American Society of Clinical Oncology

Sex: All

Age: 60+

Code: NCT06377852

Phase 3, Recruiting
Active & Responsive

Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue

for
Tongue Neoplasms, Tongue Cancer, Oral Cancer
Location: Ann Arbor MI
Sponsor: University of Michigan

Sex: All

Age: 18+

Code: NCT02584270

Recruiting
Active & Responsive

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

for
Non Small Cell Lung Cancer, Pancreatic Ductal Adenocarcinoma
Location: Fairfax VA, Huntersville NC, Nashville TN,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05431270

Phase 1, Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer