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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for
Myelodysplastic Syndromes
Location: Halifax, New Haven CT, Westbury NY, Columbia MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06499285

Phase3, Recruiting

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

for
Glioma
Location: Manhasset NY, Dallas TX, San Antonio TX
Sponsor: Plus Therapeutics

Sex: All

Age: 18+

Code: NCT01906385

Phase1, Phase2, Recruiting

Integrated Molecular and Clinical Profiling to Improve Disease Characterization and Outcome Prediction in Nodal Marginal Zone Lymphoma

for
Nodal Marginal Zone Lymphoma
Location: New York NY, Miami FL, Toronto, Columbus OH,
Sponsor: International Extranodal Lymphoma Study Group (IELSG)

Sex: All

Age: 18+

Code: NCT05700149

Recruiting

Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06600906

Recruiting

Palbociclib and Pembrolizumab in Sarcoma

for
Sarcoma
Location: Iowa City IA
Sponsor: John Rieth

Sex: All

Age: 12+

Code: NCT06113809

Phase1, Recruiting

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Alcohol and "Heat of the Moment" Sexual Decision Making

for
Alcohol Drinking, Sex, Unsafe, Hiv
Location: Boston MA
Sponsor: Boston University Charles River Campus

Sex: Male

Age: 18+

Code: NCT05729256

Recruiting

Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy People for the Expansion of T Cells for Adoptive Cell Therapy

for
Healthy Volunteer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02821806

Recruiting

An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures

for
Focal Onset Seizure, Primary Generalized Epilepsy
Location: Hackensack NJ, Middletown NY, Bethesda MD,
Sponsor: Praxis Precision Medicines

Sex: All

Age: 18 - 70+

Code: NCT06908356

Phase2, Recruiting

Continuous Glucose Monitor Use in Pregnancy

for
Type 2 Diabetes Treated With Insulin, Pregnancy, High Risk
Location: Worcester MA
Sponsor: University of Massachusetts, Worcester

Sex: Female

Age: 18+

Code: NCT05317585

Recruiting

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

for
Recurrent Diffuse Large B-Cell Lymphoma,
Location: Richmond VA, Columbus OH, Minneapolis MN
Sponsor: Yazeed Sawalha

Sex: All

Age: 18+

Code: NCT06536049

Phase1, Phase2, Recruiting

Fluorescent Intra-operative Tumor Margin Examination

for
Sarcoma
Location: Pittsburgh PA
Sponsor: Kurt Weiss

Sex: All

Age: 18 - 70+

Code: NCT04719156

Phase2, Recruiting

PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

for
NSCLC Stage II, NSCLC, Stage III
Location: Galveston TX, Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT06945484

Recruiting

Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

for
Recurrent Glioblastoma, Recurrent WHO Grade 4 Glioma
Location: Rochester MN
Sponsor: Academic and Community Cancer Research United

Sex: All

Age: 18+

Code: NCT06160206

Phase2, Recruiting

Safety Study of MucoCept-CVN

for
HIV -1 Infection
Location: San Francisco CA
Sponsor: Craig Cohen, MD, MPH

Sex: Female

Age: 18 - 45

Code: NCT07181486

Phase1, Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

for
GATA2, Immunodeficiency, MDS
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 6 - 70

Code: NCT01861106

Phase2, Recruiting

Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)

for
Primary Ovarian Insufficiency, Azoospermia, Oligospermia
Location: Bethesda MD, Rockville MD
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All

Age: 18 - 70+

Code: NCT07357701

Recruiting

Trial of Differential Margins in Single Isocenter Radiosurgery of Brain Metastases

for
Brain Metastases
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 19+

Code: NCT06857006

Recruiting

A Study of Neuropathy Caused by Enfortumab Vedotin in People With Urothelial Carcinoma

for
Neuropathy, Urothelial Carcinoma,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07390617

Recruiting

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

for
HIV, Kaposi's Sarcoma, Lymphomas,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT00006518

Recruiting

Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC

for
Chemotherapy-induced Nausea and Vomiting
Location: Bethesda MD, Gettysburg PA, Miami Lakes FL, Savannah GA,
Sponsor: Xiamen LP Pharmaceutical Co., Ltd

Sex: All

Age: 18+

Code: NCT05199818

Phase3, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer