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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Study of Longitudinal Plasma PD-L1 Testing With Immunotherapy in Lung Cancer

for
Lung Cancer (NSCLC)
Location: Kingsport TN
Sponsor: Ballad Health

Sex: All

Age: 0+

Code: NCT06849518

Recruiting

Safety and Efficacy of OT-82 in Participants With Relapsed or Refractory Lymphoma

for
Lymphoma, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell,
Location: Philadelphia PA, Miami FL, Buffalo NY, Cleveland OH,
Sponsor: Oncotartis, Inc.

Sex: All

Age: 18+

Code: NCT03921879

Phase1, Recruiting

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

for
Myeloid Leukemia, Philadelphia Positive
Location: Boston MA, New York NY, Philadelphia PA, Cincinnati OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 1 - 17

Code: NCT04925479

Phase1, Phase2, Recruiting

Markers of Prognosis and Response to Therapy in Patients With Metastatic Brain Tumors Undergoing Stereotactic Radiosurgery (SRS)

for
Metastatic Brain Tumor
Location: Seattle WA
Sponsor: Swedish Medical Center

Sex: All

Age: 19 - 70+

Code: NCT01908179

Recruiting

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT06777979

Phase1, Recruiting

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A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for
Relapsed or Refractory Multiple Myeloma (RRMM)
Location: Halifax, Boston MA, New York NY, Montreal,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06615479

Phase3, Recruiting

Study of NEROFE, a Novel Hormone-Peptide in Adult Patients With Advanced MDS and AML

for
Advanced MDS, AML
Location: Miami FL
Sponsor: Immune System Key Ltd

Sex: All

Age: 18+

Code: NCT04365179

Phase1, Recruiting

Post-Transplant Maintenance Therapy With Isatuximab Plus Lenalidomide for High-Risk Multiple Myeloma Patients

for
Multiple Myeloma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT05776979

Phase2, Recruiting

MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer

for
Prostate Disease, Elevated Prostate Specific Antigen,
Location: Lake Success NY, New York NY
Sponsor: Ardeshir Rastinehad

Sex: Male

Age: 18+

Code: NCT04599218

Recruiting

Ultrasound Imaging, Spectroscopy and Ultrasound Imaging of Vascular Blood Flow as Early Indicators of Breast Cancer Response to Neoadjuvant Treatment.

for
Breast Cancer Invasive
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: Female

Age: 0+

Code: NCT00437879

Recruiting

Feasibility of Integrating the Outcomes4Me Smartphone Navigation Application Into the Care Management of Breast Cancer Patients

for
Breast Cancer, Invasive Breast Cancer, Metastatic Breast Cancer,
Location: Boston MA
Sponsor: Outcomes4Me

Sex: All

Age: 18+

Code: NCT04262518

Recruiting

Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

for
HIV Infections, Cognitive Impairment
Location: Aurora CO, Seattle WA
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 50 - 70+

Code: NCT06013579

Recruiting

Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence

for
Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia,
Location: Nashville TN
Sponsor: University of Tennessee

Sex: All

Age: 18+

Code: NCT04663100

Recruiting

Digital Rectal Exam Proficiency Tool

for
Prostatic Hyperplasia, Prostate Cancer
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: Male

Age: 30 - 70+

Code: NCT02278679

Recruiting

The ONE-MIND Study: Evaluating the Efficacy of Online Mindfulness-Based Cancer Recovery During Chemotherapy Treatment

for
Breast Cancer, Colorectal Cancer, Chemotherapy Effect
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT03484000

Recruiting

Calcitonin Pre-treatment to Improve SPECT-CT Sensitivity

for
Primary Hyperparathyroidism, Hypercalcemia
Location: Toledo OH
Sponsor: Joseph Sferra

Sex: All

Age: 18+

Code: NCT03935984

Recruiting

Effects of Computer-Assisted Cognitive Rehabilitation Programs With Breast Cancer Survivors

for
Cognitive Impairment, Breast Cancer
Location: Houston TX
Sponsor: Texas Woman's University

Sex: All

Age: 18 - 70+

Code: NCT04027400

Recruiting

Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

for
Advanced Unresectable Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, Philadelphia PA, Baltimore MD, Columbus OH,
Sponsor: TopAlliance Biosciences

Sex: All

Age: 18+

Code: NCT04137900

Phase1, Recruiting

Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY)

for
Chemotherapy-induced Peripheral Neuropathy
Location: Burlington VT, Philadelphia PA, Baltimore MD,
Sponsor: Disarm Therapeutics

Sex: All

Age: 18+

Code: NCT03997981

Recruiting

Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Richter Syndrome,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05388006

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer