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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Advanced Wireless Sensors for Neonatal Care in the Delivery Room

for
Sudden Unexplained Infant Death, Apnea of Newborn,
Location: Montreal
Sponsor: Guilherme Sant'Anna, MD

Sex: All

Age: 0

Code: NCT06693817

Recruiting

Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC

for
NSCLC Stage IV, ALK Fusion Protein Expression
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT05950139

Phase 1, Phase 2, Recruiting

MRI-Guided Cryoablation for Focal Native Prostate Cancer

for
Primary Malignant Neoplasm of Prostate (Diagnosis)
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: Male

Age: 30 - 70+

Code: NCT04797039

Recruiting

Psychoeducational Intervention for Patients With Hepatocellular Carcinoma

for
Hepatocellular Carcinoma
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06541990

Recruiting

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for
AL Amyloidosis
Location: Boston MA, Guilford CT, Hartford CT, North Haven CT,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06022939

Phase 3, Recruiting

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Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Mineola NY, New York NY, Baltimore MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05896839

Phase 1, Phase 2, Recruiting

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

for
Multiple Myeloma
Location: Jacksonville FL, Encinitas CA, Alhambra CA,
Sponsor: Oncotherapeutics

Sex: All

Age: 18+

Code: NCT03110822

Phase 1, Recruiting

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

for
Advanced Metastatic Castration-resistant Prostate Cancer,
Location: Sherbrooke, Montreal, Toronto, Hamilton, Vancouver
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06217822

Phase 1, Recruiting

A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

for
Multiple Myeloma, Monoclonal Gammopathy of Renal Significance
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06083922

Phase 2, Recruiting

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

for
Sarcoma, Bone Sarcoma, Soft Tissue Sarcoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06129903

Recruiting

Patient Preferences for Barrett's Esophagus and Esophageal Cancer Screening Tests

for
Gastro Esophageal Reflux Disease, Barrett Esophagus
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT06693622

Recruiting

Breast Cancer Endocrine Therapy FITness (BE-FIT) Trial.

for
Breast Neoplasms
Location: Vancouver
Sponsor: University of British Columbia

Sex: Female

Age: 19 - 70+

Code: NCT04824339

Recruiting

Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Columbus OH
Sponsor: Kerry Rogers

Sex: All

Age: 18+

Code: NCT06466122

Phase 2, Recruiting

Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps

for
Colorectal Carcinoma
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 21+

Code: NCT06376565

Recruiting

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

for
Small-cell Lung Cancer, Small Cell Lung Carcinoma
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT05450965

Phase 2, Recruiting

Prostate Active Surveillance Study

for
Prostatic Neoplasms
Location: Boston MA, Norfolk VA, Atlanta GA, Ann Arbor MI,
Sponsor: University of Washington

Sex: Male

Age: 21+

Code: NCT00756665

Recruiting

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

for
Non Hodgkin Lymphoma (NHL), Mantle Cell Lymphoma (MCL),
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18 - 70+

Code: NCT04186520

Phase 1, Phase 2, Recruiting

Prospective Breast Cancer Biospecimen Collection

for
Breast Cancer, Invasive Breast Cancer,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT04074720

Recruiting

A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL

for
Relapsed Hodgkin Lymphoma, Refractory Hodgkin Lymphoma,
Location: Indianapolis IN
Sponsor: Rita Assi

Sex: All

Age: 18+

Code: NCT06484920

Phase 2, Recruiting

BOLD-100 in Combination With FOLFOX With or Without Bevacizumab for the Treatment of Advanced, Solid Tumours

for
Colorectal Cancer, Pancreatic Cancer, Gastric Cancers,
Location: Montreal, Ottawa, Toronto, Hamilton, Edmonton
Sponsor: Bold Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04421820

Phase 1, Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer