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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study

for
Stage D Heart Failure
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT04191681

Recruiting

Test-retest Evaluation of [18F]F-AraG PET

for
Non-small Cell Lung Cancer
Location: Iowa City IA
Sponsor: CellSight Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06084806

Phase2, Recruiting

Pre-habilitation to Improve Outcomes in Patients Undergoing Liver Resection for Cancer

for
Colorectal Neoplasm, Biliary Tract Neoplasm, Liver Neoplasm
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18 - 70+

Code: NCT01542281

Recruiting

I-125 Versus Pd-103 for Medium Risk Prostate Cancer

for
Prostate Cancer
Location: Seattle WA
Sponsor: VA Puget Sound Health Care System

Sex: Male

Age: 40 - 70+

Code: NCT00486499

Phase3, Recruiting

A Study of Pembrolizumab+ sEphB4 in Metastatic Urothelial Carcinoma

for
Metastatic Urothelial Carcinoma
Location: Santa Monica CA
Sponsor: Vasgene Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT04486781

Phase2, Recruiting

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Informing Oral Nicotine Pouch Regulations to Promote Public Health

for
Tobacco-Related Carcinoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 21+

Code: NCT06315881

Phase2, Recruiting

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

for
T-cell Acute Lymphoblastic Leukemia
Location: Chicago IL
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18+

Code: NCT05289687

Phase2, Recruiting

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 18

Code: NCT06247787

Phase1, Recruiting

Beacon Sensors and Telerehabilitation to Assess and Improve Use of Devices (BeST-AID) for Low Vision

for
Low Vision, Low Vision Aids
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18+

Code: NCT06107881

Recruiting

Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failure

for
Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia
Location: Clovis CA, Sacramento CA
Sponsor: Brian Jonas

Sex: All

Age: 18+

Code: NCT04905810

Phase2, Recruiting

A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers

for
Squamous Cell Carcinoma of Head and Neck
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06085781

Recruiting

Potency pReservation In Prostate cAncer Patients Treated With UltraSound-guided Low-dose Rate Brachytherapy

for
Prostate Cancer
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: Male

Age: 18 - 70+

Code: NCT04718987

Recruiting

Tissue Collection Protocol for Gastroesophageal Cancers

for
Esophageal Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT02495337

Recruiting

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

for
Follicular Lymphoma, Mantle Cell Lymphoma, Hairy Cell Leukemia,
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06340737

Phase1, Recruiting

CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee

for
Revision Total Hip Arthroplasty (RTHA),
Location: Greater Sudbury
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT05828810

Recruiting

Cancer Prevention in Women With a BRCA Mutation

for
BRCA1 Gene Mutation, BRCA2 Gene Mutation, Breast Cancer,
Location: Toronto
Sponsor: Women's College Hospital

Sex: Female

Age: 35 - 70

Code: NCT02225015

Phase1, Recruiting

High Resolution Microendoscopy for the Detection of Esophageal Squamous Cell Neoplasia

for
Suspected or Known Squamous Cell Neoplasia,
Location: Houston TX
Sponsor: Anandasabapathy, Sharmila, M.D.

Sex: All

Age: 18+

Code: NCT02029937

Phase2, Recruiting

Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy

for
Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
Location: Los Angeles CA, Santa Monica CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 0 - 18

Code: NCT06189781

Recruiting

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

for
Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD, Nashville TN, Chicago IL, Houston TX,
Sponsor: Nurix Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04830137

Phase1, Recruiting

Concordance Between Liquid and Tissue Biopsy

for
Breast Neoplasms
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT04241237

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer