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Oncology Clinical Trials

Browse 9,252 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies

for
Myelodysplastic Syndromes, MDS/MPN Crossover Syndromes
Location: Cleveland OH
Sponsor: Benjamin Tomlinson

Sex: All

Age: 18+

Code: NCT04187703

Early Phase 1, Recruiting

Effects of Computer-Assisted Cognitive Rehabilitation Programs With Breast Cancer Survivors

for
Cognitive Impairment, Breast Cancer
Location: Houston TX
Sponsor: Texas Woman's University

Sex: All

Age: 18 - 70+

Code: NCT04027400

Recruiting

Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique

for
Brain Metastases
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT05045950

Phase 2, Recruiting

Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

for
Hodgkin Lymphoma, Relapsed or Refractory Hodgkin Lymphoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT03618550

Phase 2, Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

for
Thyroid Gland Follicular Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06440850

Phase 2, Recruiting

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Pre-Habilitation with Mindfulness and Exercise for Patients Undergoing Radical Cystectomy (PRIMER Trial)

for
Bladder Cancer, Non-muscle-invasive Bladder Cancer,
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18 - 70+

Code: NCT05790850

Recruiting

Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

for
Advanced Unresectable Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, Philadelphia PA, Baltimore MD, Columbus OH,
Sponsor: TopAlliance Biosciences

Sex: All

Age: 18+

Code: NCT04137900

Phase 1, Recruiting

Assessing Patient Satisfaction and Confidence After Use of Educational Video to Augment Surgical Consent for Thyroid Surgery

for
Thyroid Cancer
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT06918223

Recruiting

CT Perfusion Scans in Detecting Changes in Blood Flow to the Liver After Portal Vein Embolization

for
Liver and Intrahepatic Bile Duct Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03990623

Recruiting

Circulating Tumor Cells (CTCs): A Potential Screening Test for Clinically Undetectable Breast Carcinoma

for
Breast Abnormality
Location: Washington DC
Sponsor: Walter Reed Army Medical Center

Sex: All

Age: 18+

Code: NCT01322750

Recruiting

Cryoablation of Small Breast Tumors in Early Stage Breast Cancer

for
Breast Cancer
Location: Providence RI, Wynnewood PA, Miami FL, Naples FL,
Sponsor: Sanarus Technologies, Inc.

Sex: Female

Age: 50+

Code: NCT01992250

Recruiting

Teamwork Makes the Dream Work

for
HIV Infections, Inpatient Facility Diagnoses
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 18+

Code: NCT05866523

Recruiting

Test-retest Evaluation of [18F]F-AraG PET

for
Non-small Cell Lung Cancer
Location: Iowa City IA
Sponsor: CellSight Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06084806

Phase 2, Recruiting

I-125 Versus Pd-103 for Medium Risk Prostate Cancer

for
Prostate Cancer
Location: Seattle WA
Sponsor: VA Puget Sound Health Care System

Sex: Male

Age: 40 - 70+

Code: NCT00486499

Phase 3, Recruiting

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

for
T-cell Acute Lymphoblastic Leukemia
Location: Chicago IL
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18+

Code: NCT05289687

Phase 2, Recruiting

A Study of HB0045 Injection in Patients With Advanced Solid Tumors

for
Solid Tumor, Adult
Location: Canton OH
Sponsor: Shanghai Huaota Biopharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT06056323

Phase 1, Phase 2, Recruiting

MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

for
Rectal Adenocarcinoma
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT04808323

Phase 1, Recruiting

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 18

Code: NCT06247787

Phase 1, Recruiting

Thymoglobulin in Unrelated Hematopoietic Progenitor Cell Transplantation

for
Hematologic Malignancies
Location: Halifax, Montreal, Hamilton, Winnipeg, Vancouver
Sponsor: McMaster University

Sex: All

Age: 16 - 70

Code: NCT01217723

Phase 3, Recruiting

Potency pReservation In Prostate cAncer Patients Treated With UltraSound-guided Low-dose Rate Brachytherapy

for
Prostate Cancer
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: Male

Age: 18 - 70+

Code: NCT04718987

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer