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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

for
Epilepsy, Temporal Lobe
Location: Orange CA, Los Angeles CA, San Diego CA, Palo Alto CA,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06422923

Phase1, Phase2, Recruiting

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for
Hepatocellular Carcinoma
Location: Orange CA, Los Angeles CA, Aurora CO, Spokane WA,
Sponsor: Tvardi Therapeutics, Incorporated

Sex: All

Age: 18+

Code: NCT05440708

Phase1, Phase2, Recruiting

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

for
Chronic Kidney Disease
Location: San Dimas CA, San Ramon CA, El Paso TX, Spokane WA,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18+

Code: NCT06717698

Phase2, Recruiting

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

for
Prediabetic State, Atherosclerosis, Metformin
Location: Long Beach CA, Loma Linda CA, West Los Angeles CA,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT02915198

Recruiting

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for
Relapsed or Refractory Multiple Myeloma (RRMM)
Location: Orange CA, Los Angeles CA, Salt Lake City UT, Vancouver,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06615479

Phase3, Recruiting

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Evaluation of Fever Occurring in Labor in Patients Receiving Epidural Anesthesia

for
Fever
Location: Orange CA, Long Beach CA
Sponsor: MemorialCare

Sex: Female

Age: 18+

Code: NCT00326521

Recruiting

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Long Beach CA, Eugene OR, Lone Tree CO, Vancouver WA,
Sponsor: Puma Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT06095505

Phase2, Recruiting

Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors

for
Solid Tumor
Location: Orange CA, Santa Monica CA, Gilbert AZ, Irving TX,
Sponsor: ImmunoGenesis

Sex: All

Age: 18+

Code: NCT06014502

Phase1, Recruiting

Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

for
Delayed Graft Function, DGF, Kidney Transplant
Location: Los Angeles CA, Phoenix AZ, Stanford CA,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06830798

Phase3, Recruiting

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for
Advanced Biliary Tract Cancer, Biliary Tract Cancer (BTC)
Location: Orange CA, Duarte CA, Las Vegas NV, Seattle WA,
Sponsor: J-Pharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT07265674

Phase3, Recruiting

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

for
Lung Diseases, Interstitial
Location: Orange CA, Upland CA, Los Angeles CA, San Francisco CA,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06572384

Phase3, Recruiting

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

for
Coronary Artery Disease
Location: Glendale CA, Dallas TX, Memphis TN, Nashville TN,
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT06399705

Phase3, Recruiting

A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma

for
Advanced Hepatocellular Carcinoma
Location: Duarte CA, Seattle WA, Dallas TX, Houston TX,
Sponsor: Iterion Therapeutics

Sex: All

Age: 18+

Code: NCT05797805

Phase1, Phase2, Recruiting

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for
Cancer Harboring BRAF Alterations, HGG, LGG, Solid Tumors
Location: Beverly Hills CA, Westwood, Los Angeles CA,
Sponsor: Fore Biotherapeutics

Sex: All

Age: 8+

Code: NCT05503797

Phase2, Recruiting

Retinoblastoma Patient Clinical Database and Tissue Repository

for
Retinoblastoma, Retinoblastoma Bilateral,
Location: Los Angeles CA, Phoenix AZ, Portland OR, Seattle WA,
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 0 - 18

Code: NCT04959097

Recruiting

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

for
Non-muscle Invasive Bladder Cancer
Location: Orange CA, Bakersfield CA, Phoenix AZ, Queen Creek AZ,
Sponsor: Protara Therapeutics

Sex: All

Age: 18+

Code: NCT05951179

Phase2, Recruiting

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for
Stage II Nasopharyngeal Carcinoma AJCC v8,
Location: Downey CA, Los Angeles CA, Loma Linda CA, San Diego CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 21

Code: NCT06064097

Phase2, Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

for
Focal Onset Seizures
Location: Orange CA, Downey CA, Los Angeles CA, Boise ID,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT05716100

Phase3, Recruiting

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

for
Arterial Disease of Legs, Below-the-knee Obstruction,
Location: Los Angeles CA, Scottsdale AZ, Seattle WA, Austin TX,
Sponsor: Concept Medical Inc.

Sex: All

Age: 21+

Code: NCT06182397

Recruiting

An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

for
Recurrent Pericarditis
Location: Orange CA, Salt Lake City UT, Seattle WA, Houston TX,
Sponsor: Zomagen Biosciences Ltd.

Sex: All

Age: 18 - 70+

Code: NCT06836232

Phase2, Recruiting