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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for
Non-Small Cell Lung Cancer
Location: Fountain Valley CA, Anaheim CA, Beverly Hills CA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06357533

Phase3, Recruiting

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

for
Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Location: Fountain Valley CA, Orange CA, Long Beach CA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT05519475

Phase2, Recruiting

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

for
Metabolic Dysfunction Associated Steatohepatitis
Location: Fountain Valley CA, Orange CA, Montclair CA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT06632457

Phase3, Recruiting

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

for
Metabolic Dysfunction Associated Steatohepatitis (MASH),
Location: Fountain Valley CA, Orange CA, Long Beach CA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT06632444

Phase3, Recruiting

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer,
Location: Fountain Valley CA, Laguna Hills CA, Anaheim CA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222566

Phase3, Recruiting

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BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

for
HR+/HER2- Breast Cancer
Location: Fountain Valley CA, Los Angeles CA, Oxnard CA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07492641

Phase3, Recruiting

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

for
Alzheimer Disease, Alzheimer Disease Due to P. Gingivalis
Location: Orange CA, Riverside CA, Sherman Oaks CA, Phoenix AZ,
Sponsor: Lighthouse Pharmaceuticals, Inc.

Sex: All

Age: 55 - 70+

Code: NCT06847321

Phase2, Recruiting

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

for
Major Depressive Disorder
Location: Orange CA, Anaheim CA, Long Beach CA, West Covina CA,
Sponsor: Autobahn Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT06633016

Phase2, Recruiting

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

for
Bipolar Disorder
Location: Orange CA, Clinton UT, Bellevue WA, Richardson TX,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07286175

Phase2, Recruiting

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

for
Bipolar Disorder, Bipolar Depression, Bipolar I Disorder,
Location: Orange CA, Bellflower CA, Riverside CA, Culver City CA,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT07172516

Phase3, Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease

for
Alzheimer's Disease
Location: Orange CA, Long Beach CA, Garden Grove CA, Las Vegas NV,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 55 - 70+

Code: NCT07011745

Phase3, Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

for
Non Small Cell Lung Cancer
Location: Orange CA, Newport Beach CA, Beverly Hills CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312137

Phase3, Recruiting

A Long-term Extension Study of PCI-32765 (Ibrutinib)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma,
Location: Orange CA, Eugene OR, Sioux Falls SD, Columbus OH
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT01804686

Phase3, Recruiting

A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)

for
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Location: Orange CA, Montclair CA, Garden Grove CA, Las Vegas NV,
Sponsor: Rivus Pharmaceuticals, Inc.

Sex: All

Age: 30+

Code: NCT07491458

Phase2, Recruiting

Prospective, Open-label, Non-significant Risk, Multicenter Study Comparing the Polyp Detection of the Study Device to That of the Colonoscopy Reference

for
Colonic Polyps
Location: Orange CA, Lancaster CA, Chula Vista CA, Naperville IL,
Sponsor: Capso Vision, Inc.

Sex: All

Age: 45 - 70+

Code: NCT07089615

Recruiting

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for
Venous Thromboembolism, Deep Venous Thrombosis,
Location: Orange CA, Pasadena CA, Las Vegas NV, Scottsdale AZ,
Sponsor: Inari Medical

Sex: All

Age: 18+

Code: NCT05701917

Recruiting

Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:

for
Parkinson Disease
Location: Aliso Viejo CA, Irvine CA, Palo Alto CA, Boca Raton FL,
Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07219927

Recruiting

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

for
Ventricular Ejection Fraction, LVF, LV Dysfunction,
Location: Orange CA, Pasadena CA, Austin TX, Weslaco TX,
Sponsor: Peerbridge Health, Inc

Sex: All

Age: 18+

Code: NCT06699056

Recruiting

ATLAS (AltaValve) Pivotal Trial

for
Mitral Regurgitation, Mitral Insufficiency,
Location: Orange CA, Los Angeles CA, La Jolla CA,
Sponsor: 4C Medical Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06465745

Recruiting

The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis

for
Autoimmune Encephalitis, Encephalitis
Location: Orange CA, Phoenix AZ, Scottsdale AZ, Sacramento CA,
Sponsor: University of Utah

Sex: All

Age: 12+

Code: NCT04372615

Phase2, Recruiting