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Paid Clinical Trials Irvine

Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

for
Capsular Contracture Associated With Breast Implant,
Location: Newport Beach CA, Huntington Beach CA, Pasadena CA,
Sponsor: C. R. Bard

Sex: Female

Age: 22 - 70

Code: NCT05945329

Recruiting
Active & Responsive

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for
Obesity, Overweight
Location: Santa Ana CA, Fountain Valley CA, Long Beach CA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07684235

Phase3, Recruiting
Active & Responsive

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

for
Obesity or Overweight
Location: Santa Ana CA, Rolling Hills Estates CA, Rialto CA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07575399

Phase3, Recruiting
Active & Responsive

A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

for
Atopic Dermatitis
Location: Newport Beach CA, Huntington Beach CA, Los Angeles CA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT05995964

Phase2, Recruiting
Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Irvine CA, Duarte CA, West Valley City UT,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase1, Phase2, Recruiting

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Active & Responsive

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for
Triple Negative Breast Neoplasms
Location: Irvine CA, Duarte CA, Los Angeles CA, Las Vegas NV,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06841354

Phase3, Recruiting
Active & Responsive

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for
Ductal Carcinoma in Situ
Location: Irvine CA, Duarte CA, South Pasadena CA, Los Angeles CA,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female

Age: 18+

Code: NCT06075953

Phase2, Recruiting
Active & Responsive

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for
Myelofibrosis; Anemia, Anemia, Myelofibrosis,
Location: Irvine CA, Duarte CA, Los Angeles CA, Gilbert AZ,
Sponsor: Disc Medicine, Inc

Sex: All

Age: 18+

Code: NCT05320198

Phase1, Phase2, Recruiting
Active & Responsive

A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Irvine CA, Huntington Beach CA, Long Beach CA,
Sponsor: City of Hope Medical Center

Sex: Female

Age: 18+

Code: NCT07741968

Recruiting
Active & Responsive

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for
Extensive Stage Lung Small Cell Carcinoma,
Location: Irvine CA, Duarte CA, La Jolla CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06287775

Phase1, Phase2, Recruiting
Active & Responsive

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for
Prostate Cancer, Prostatic Neoplasms
Location: Irvine CA, Orange CA, Long Beach CA, Duarte CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: Male

Age: 18+

Code: NCT06925737

Phase3, Recruiting
Active & Responsive

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

for
Type 2 Diabetes
Location: Santa Ana CA, Phoenix AZ, Rexburg ID, Redmond WA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06897475

Phase2, Recruiting
Active & Responsive

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

for
Colorectal Cancer
Location: Fountain Valley CA, Salt Lake City UT, Seattle WA,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05234177

Recruiting
Active & Responsive

A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes

for
Diabetes Mellitus, Type 2
Location: Fountain Valley CA, Long Beach CA, Montclair CA,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18 - 70+

Code: NCT07668388

Phase2, Recruiting
Active & Responsive

A Study of Brenipatide in Participants With Opioid Use Disorder

for
Opioid Use Disorder
Location: Fountain Valley CA, Phoenix AZ, San Francisco CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07420283

Phase2, Recruiting
Active & Responsive

Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

for
Hemophilia B
Location: Orange CA, Memphis TN, Atlanta GA, Ann Arbor MI,
Sponsor: CSL Behring

Sex: Male

Age: 11 - 17

Code: NCT07080905

Phase3, Recruiting
Active & Responsive

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

for
Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia
Location: Orange CA, Redwood City CA, Seattle WA, Kansas City MO,
Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois

Sex: All

Age: 0 - 70+

Code: NCT05500807

Phase1, Recruiting
Active & Responsive

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for
Atopic Dermatitis
Location: Fountain Valley CA, Los Angeles CA, Portland OR,
Sponsor: Apogee Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07003425

Phase2, Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Orange CA, Chino CA, Glendale CA, La Jolla CA,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase2, Recruiting
Active & Responsive

A Study to Evaluate the Effect of KarXT on Urological Safety

for
Schizophrenia
Location: Orange CA, Garden Grove CA, Bellflower CA, Las Vegas NV,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07221877

Recruiting