Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,581
Active & Responsive
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
for
Depressive Disorder, Major
Location: Orange CA, Moorpark CA, Las Vegas NV, Clinton UT,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18 - 70+
Code: NCT07412756
Phase3, Recruiting
Active & Responsive
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
for
Post Traumatic Stress Disorder
Location: Orange CA, San Juan Capistrano CA, Montclair CA,
Sponsor: Transcend Therapeutics
Sex: All
Age: 18+
Code: NCT07456696
Phase3, Recruiting
Active & Responsive
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
for
Major Depressive Disorder (MDD), Depression in Adults,
Location: Orange CA, Santa Monica CA, Glendale CA, Los Angeles CA,
Sponsor: Cybin IRL Limited
Sex: All
Age: 18 - 70+
Code: NCT06793397
Phase3, Recruiting
Active & Responsive
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
Location: Orange CA, Phoenix AZ, San Francisco CA, Dallas TX,
Sponsor: Carl Allen
Sex: All
Age: 0+
Code: NCT04079179
Phase2, Recruiting
Active & Responsive
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
for
Acute Myeloid Leukemia
Location: Orange CA, Long Beach CA, Las Vegas NV, Phoenix AZ,
Sponsor: PedAL BCU, LLC
Sex: All
Age: 0 - 21
Code: NCT05183035
Phase3, Recruiting
Active & Responsive
Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).
for
IGF1 Deficiency
Location: Orange CA, Cincinnati OH, Miami FL
Sponsor: Esteve Pharmaceuticals, S.A.
Sex: All
Age: 2 - 18
Code: NCT00903110
Recruiting
Active & Responsive
A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome
for
Dravet Syndrome
Location: Orange CA, Los Angeles CA, Phoenix AZ, San Francisco CA,
Sponsor: Stoke Therapeutics, Inc
Sex: All
Age: 2 - 17
Code: NCT06872125
Phase3, Recruiting
Active & Responsive
TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
for
Lymphoblastic Leukemia
Location: Orange CA, Los Angeles CA, Madera CA, Phoenix AZ,
Sponsor: Tanja Andrea Gruber
Sex: All
Age: 0 - 1
Code: NCT05848687
Phase1, Phase2, Recruiting
Active & Responsive
A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
for
Moderate to Severe Glabellar Lines
Location: Newport Beach CA, Pasadena CA, Los Angeles CA,
Sponsor: Ipsen
Sex: All
Age: 18+
Code: NCT07435428
Phase3, Recruiting
Active & Responsive
A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension
for
Primary Open Angle Glaucoma (POAG), Ocular Hypertension (OH)
Location: Newport Beach CA
Sponsor: YS Life Science Co., Ltd.
Sex: All
Age: 18+
Code: NCT07661329
Phase3, Recruiting
Active & Responsive
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
for
Metastatic Dedifferentiated Liposarcoma,
Location: Newport Beach CA, Los Angeles CA, Pasadena CA,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT06422806
Phase3, Recruiting
Active & Responsive
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
for
Glioblastoma
Location: Orange CA, Los Angeles CA, La Jolla CA,
Sponsor: Global Coalition for Adaptive Research
Sex: All
Age: 18+
Code: NCT03970447
Phase2, Phase3, Recruiting
Active & Responsive
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
for
Sickle Cell Disease
Location: Orange CA, Houston TX, Flowood MS, Chicago IL,
Sponsor: Novartis Pharmaceuticals
Sex: All
Age: 12 - 70+
Code: NCT06439082
Phase3, Recruiting
Active & Responsive
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
for
Moderate to Severe Chronic Obstructive Pulmonary Disease
Location: Newport Beach CA, La Palma CA, Northridge CA,
Sponsor: Pfizer
Sex: All
Age: 35 - 70+
Code: NCT07363694
Phase2, Phase3, Recruiting
Active & Responsive
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
for
Percutaneous Coronary Intervention,
Location: Newport Beach CA, Torrance CA, Glendora CA,
Sponsor: Duke University
Sex: All
Age: 18+
Code: NCT06909565
Recruiting
Active & Responsive
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
for
Asthma
Location: Newport Beach CA, Rolling Hills Estates CA,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18 - 70+
Code: NCT07219173
Phase2, Recruiting
Active & Responsive
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
for
Platinum-resistant Ovarian Cancer,
Location: Newport Beach CA, Orange CA, Duarte CA, La Jolla CA,
Sponsor: Genelux Corporation
Sex: Female
Age: 18+
Code: NCT05281471
Phase3, Recruiting
Active & Responsive
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
for
Bipolar Disorder Type I With Mania
Location: Orange CA, Anaheim CA, Garden Grove CA, Torrance CA,