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Paid Clinical Trials California

Discover 5,800 paid clinical trials in California. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

for
Healthy Participants, Obesity
Location: Brooklyn MD, Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 65

Code: NCT07511205

Phase 1, Recruiting
Active & Responsive

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

for
Type 1 Diabetes, New Onset
Location: New Haven CT, Miami FL, Buffalo NY, Pittsburgh PA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 9 - 20

Code: NCT07061574

Phase 1, Phase 2, Recruiting
Active & Responsive

Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease

for
Primary Sjogren's Disease
Location: Boston MA, Philadelphia PA, Willow Grove PA,
Sponsor: Vor Biopharma

Sex: All

Age: 18 - 70+

Code: NCT07404865

Phase 3, Recruiting
Active & Responsive

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

for
Type 1 Diabetes Mellitus
Location: Boston MA, New Haven CT, New York NY, Miami FL,
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All

Age: 8 - 45

Code: NCT07142252

Phase 2, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: New York NY, Orange CA
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting

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Active & Responsive

KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for
Bladder Cancer
Location: New York NY, Cleveland OH, Chicago IL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07232602

Phase 1, Phase 2, Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: Scarborough ME, Boston MA, New Haven CT,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase 2, Recruiting
Active & Responsive

Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD

for
Atopic Dermatitis, Atopic Dermatitis Eczema, Eczema,
Location: South San Francisco CA
Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07441395

Phase 2, Recruiting
Active & Responsive

Methods of Identifying Effective Off-Guideline Treatments for Advanced Cancer Patients

for
Advanced Cancer
Location: Palo Alto CA
Sponsor: Cancer Commons

Sex: All

Age: 0+

Code: NCT07343024

Recruiting
Active & Responsive

Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer Stage IIIC,
Location: Truckee CA, Chico CA, Marysville CA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT07250477

Phase 2, Recruiting
Active & Responsive

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Detroit MI, Houston TX, Santa Fe NM, Irvine CA,
Sponsor: Xerient Pharma

Sex: All

Age: 18+

Code: NCT07157033

Phase 1, Phase 2, Recruiting
Active & Responsive

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for
Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Norwich CT, New York NY, Hackensack NJ, Fairfax VA,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07397338

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

for
Amyotrophic Lateral Sclerosis
Location: Worcester MA, Philadelphia PA, Baltimore MD,
Sponsor: Insmed Gene Therapy LLC

Sex: All

Age: 18 - 70+

Code: NCT07290062

Phase 1, Recruiting
Active & Responsive

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

for
PIK3CA-related Overgrowth Spectrum (PROS)
Location: Chapel Hill NC, Pittsburgh PA, Columbus OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 2 - 70+

Code: NCT06997588

Phase 2, Recruiting
Active & Responsive

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for
Spinal Muscular Atrophy (SMA)
Location: Boston MA, Hartford CT, New York NY, Hillsborough NC,
Sponsor: argenx

Sex: All

Age: 5 - 17

Code: NCT07287982

Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

for
Multiple Myeloma, Relapsed/Refractory Multiple Myeloma
Location: Boston MA, New York NY, Chapel Hill NC, Jacksonville FL,
Sponsor: C4 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07284758

Phase 2, Recruiting
Active & Responsive

A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

for
IO Resistant Squamous and Nonsquamous NSCLC
Location: New York NY, Washington D.C. DC, Margate FL, Tamarac FL,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07217301

Phase 3, Recruiting
Active & Responsive

IKS014 in Advanced Solid Tumors That Express HER2

for
Breast Cancer, Gastric Cancer, Gastroesophageal-junction Cancer
Location: Boston MA, Nashville TN, Fort Worth TX,
Sponsor: Iksuda Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT05872295

Phase 1, Recruiting
Active & Responsive

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

for
Methamphetamine Intoxication, Methamphetamine Disorders,
Location: Glendale CA
Sponsor: Clear Scientific, Inc.

Sex: All

Age: 18 - 55

Code: NCT06721494

Phase 2, Recruiting
Active & Responsive

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

for
Pulmonary Hypertension, Interstitial Lung Disease (ILD),
Location: Boston MA, Providence RI, Charleston SC, Greensboro NC,
Sponsor: Pulmovant, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07333183

Phase 2, Recruiting

Popular cities in California

With its extensive healthcare system and world-class medical research institutions, California is a major hub for clinical trials. Leading research centers such as UCLA Health, Stanford Medicine, the University of California, the City of Hope, San Francisco (UCSF), and the Scripps Research Institute are spearheading medical research and innovation. These institutions are at the cutting edge of clinical studies, driving advancements in groundbreaking treatments and significantly contributing to healthcare innovations across the state.

Why choose California for clinical trials?

The state of California offers a variety of benefits for participants in clinical trials. Firstly, because the state is home to leading research institutions, it provides participants with access to cutting-edge treatments and advanced medical technologies before they become widely available. These institutions are equipped with state-of-the-art facilities and staffed by top experts, ensuring high-quality care and rigorous monitoring throughout the study.

California's diverse and innovative research landscape offers a wide range of study options, enhancing the likelihood of finding a trial that matches specific health needs. Moreover, the state's adherence to stringent regulatory and ethical standards ensures that trials are conducted with the utmost integrity and participant protection.

Common conditions studied in California

Local regulations and guidelines

Benefits of participating in clinical trials

How to enroll in a clinical trial in California