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Paid Clinical Trials Chicago

Discover 2,385 paid clinical trials in Chicago, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older

for
Obesity, Depression
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 50 - 70+

Code: NCT06636058

Recruiting
Active & Responsive

A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

for
Phelan-McDermid Syndrome
Location: Chicago IL, Ann Arbor MI, Cincinnati OH, Columbus OH,
Sponsor: Neuren Pharmaceuticals Limited

Sex: All

Age: 3 - 12

Code: NCT07281079

Phase 3, Recruiting
Active & Responsive

Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.

for
Overweight (BMI > 25), Obesity (BMI>30), Hs-CRP
Location: Chicago IL
Sponsor: Midwest Center for Metabolic and Cardiovascular Research

Sex: All

Age: 21 - 70+

Code: NCT07566325

Recruiting
Active & Responsive

A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)

for
Overweight , Obesity
Location: Chicago IL, Addison IL, Bloomington IN
Sponsor: Midwest Center for Metabolic and Cardiovascular Research

Sex: All

Age: 18 - 69

Code: NCT07789769

Recruiting
Active & Responsive

Mathematical Modeling of Blood Sugar and Hormone Responses in Insulin-Dependent Type 2 Diabetes

for
Type 2 Diabetes, Insulin Dependent Diabetes
Location: Chicago IL
Sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology

Sex: All

Age: 18 - 65

Code: NCT07650682

Recruiting

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Active & Responsive

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for
Myopia
Location: Chicago IL, Bloomington IN, Columbus OH, Memphis TN,
Sponsor: Ohio State University

Sex: All

Age: 6 - 11

Code: NCT07567040

Phase 3, Recruiting
Active & Responsive

Food and Metabolism Study

for
Prediabetes, Insulin Resistance, Triglycerides,
Location: Chicago IL
Sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology

Sex: All

Age: 40 - 70

Code: NCT07624500

Recruiting
Active & Responsive

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Chicago IL, Oak Lawn IL, Park Ridge IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06589804

Phase 3, Recruiting
Active & Responsive

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for
Ampulla of Vater Carcinoma, Appendix Carcinoma,
Location: Chicago IL, Oak Lawn IL, Park Ridge IL, Indianapolis IN,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07283939

Recruiting
Active & Responsive

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Chicago IL, Oak Lawn IL, Park Ridge IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07091617

Recruiting
Active & Responsive

Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis

for
Atopic Dermatitis (AD)
Location: Chicago IL, West Lafayette IN, Bay City MI,
Sponsor: Enveda Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07298395

Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Effect of KarXT on Urological Safety

for
Schizophrenia
Location: Chicago IL, Little Rock AR, Philadelphia PA, Marlton NJ,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07221877

Phase 4, Recruiting
Active & Responsive

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

for
Generalized Anxiety Disorder
Location: Chicago IL, Novi MI, Saint Charles MO, North Canton OH,
Sponsor: Reunion Neuroscience Inc

Sex: All

Age: 18 - 70+

Code: NCT07489651

Phase 2, Recruiting
Active & Responsive

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

for
Post Traumatic Stress Disorder
Location: Chicago IL, Madison WI, Creve Coeur MO,
Sponsor: Transcend Therapeutics

Sex: All

Age: 18+

Code: NCT07456696

Phase 3, Recruiting
Active & Responsive

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for
Major Depressive Disorder
Location: Chicago IL, St Louis MO, Little Rock AR, Atlanta GA,
Sponsor: Definium Therapeutics US, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07592689

Phase 3, Recruiting
Active & ResponsiveNew

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

for
Type 2 Diabetes Mellitus
Location: Chicago IL, Maumee OH, Troy MI, Nashville TN,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07662109

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

for
Obesity or Overweight
Location: Chicago IL, Champaign IL, Columbus OH, Ames IA, Guelph,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07784725

Phase 3, Recruiting
Active & Responsive

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

for
Bipolar Disorder Type I With Mania
Location: Chicago IL, Cincinnati OH, St Louis MO, North Canton OH,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT06929273

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

for
Mania, Bipolar Disorder
Location: Chicago IL, St Louis MO, Bentonville AR, Little Rock AR,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07140913

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

for
Bipolar-I Disorder With Mania or Mania With Mixed Features
Location: Chicago IL, North Canton OH, Little Rock AR, Atlanta GA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT06951698

Phase 3, Recruiting

Chicago is a vital city for clinical research, offering a robust healthcare network and renowned medical research institutions. Major facilities such as The University of Chicago Medicine, Northwestern Medicine, and Rush University Medical Center are at the forefront of pioneering research across various fields, including cancer, cardiovascular health, and neurological disorders.

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Looking for women's health studies in Chicago? Read our guide: Top 10 Women's Health Clinical Trials in Chicago

Top 10 Women’s Health Clinical Trials in Chicago

Why choose Chicago for clinical trials?

The city of Chicago offers many advantages for individuals considering participation in clinical trials. With a diverse and vibrant population, researchers benefit from the variety of participants, improving the reliability and applicability of research findings across different demographics.

By opting to participate in a clinical trial in Chicago, individuals not only gain access to cutting-edge therapies and treatments but also contribute to vital medical research. This collaborative effort is supported by a robust clinical research infrastructure, ensuring participants receive high-quality care and attention while playing a crucial role in shaping the future of healthcare.

Common conditions studied in Chicago

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Benefits of participating in clinical trials

How to enroll in a clinical trial in Chicago