Background illustration for clinical trials search

Paid Clinical Trials Springfield

Discover 203 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

Filter
2

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

for
Castration-Resistant Prostate Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: Male

Age: 18+

Code: NCT06470243

Phase 3, Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for
Metastatic Renal Cell Carcinoma,
Location: Springfield IL, Decatur IL, Alton IL, Effingham IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05327686

Phase 2, Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05987241

Phase 2, Phase 3, Recruiting

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

for
Pancreatic Acinar Cell Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04858334

Phase 2, Recruiting

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

for
Metastatic Small Intestinal Adenocarcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04205968

Phase 2, Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for
Colorectal Cancer, Sarcopenia
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 60+

Code: NCT03998202

Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Location: Springfield IL, Chicago IL, Indianapolis IN, Madison WI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06119581

Phase 3, Recruiting

Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Springfield IL, Decatur IL, Canton IL, Normal IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 0+

Code: NCT04242095

Recruiting

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 60+

Code: NCT05976763

Phase 3, Recruiting

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for
Smoldering Plasma Cell Myeloma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT03937635

Phase 3, Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05624996

Phase 3, Recruiting

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05642572

Phase 2, Recruiting

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

for
Renal Pelvis and Ureter Urothelial Carcinoma
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04628767

Phase 2, Phase 3, Recruiting

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for
Breast Carcinoma, Colorectal Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06418204

Recruiting

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

for
Cigarette Smoking-Related Carcinoma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT05008848

Phase 3, Recruiting

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 70+

Code: NCT06096844

Phase 3, Recruiting

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for
Advanced Lung Non-Squamous Non-Small Cell Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04181060

Phase 3, Recruiting

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for
Lung Non-Small Cell Carcinoma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06116682

Phase 2, Recruiting

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for
Malignant Female Reproductive System Neoplasm,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06126276

Phase 2, Recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for
Bladder Adenocarcinoma, Bladder Clear Cell Adenocarcinoma,
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03866382

Phase 2, Recruiting