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Paid Clinical Trials Springfield

Discover 192 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for
Breast Carcinoma, Colorectal Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06418204

Recruiting

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

for
Cigarette Smoking-Related Carcinoma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT05008848

Phase3, Recruiting

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 70+

Code: NCT06096844

Phase3, Recruiting

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Springfield IL, Decatur IL, Normal IL, Peoria IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06589804

Phase3, Recruiting

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for
Advanced Lung Non-Squamous Non-Small Cell Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04181060

Phase3, Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for
Lung Non-Small Cell Carcinoma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06116682

Phase2, Recruiting

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for
Malignant Female Reproductive System Neoplasm,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06126276

Phase2, Recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for
Bladder Adenocarcinoma, Bladder Clear Cell Adenocarcinoma,
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03866382

Phase2, Recruiting

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC),
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06661720

Phase3, Recruiting

Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

for
Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8,
Location: Springfield IL, Warrenville IL, Chicago IL,
Sponsor: NRG Oncology

Sex: Female

Age: 18+

Code: NCT06388018

Phase2, Recruiting

Global Paradise System US Post Approval Study

for
Hypertension, Cardiovascular Diseases, Vascular Diseases
Location: Springfield IL, Kansas City MO, Nashville TN,
Sponsor: ReCor Medical, Inc.

Sex: All

Age: 18+

Code: NCT06297291

Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for
Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Bloomington IL,
Sponsor: NRG Oncology

Sex: Male

Age: 18+

Code: NCT05946213

Phase3, Recruiting

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

for
Irritable Bowel Syndrome, Constipation
Location: Springfield IL, New Albany IN, Louisville KY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07545772

Phase2, Recruiting

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

for
Irritable Bowel Syndrome, Diarrhea
Location: Springfield IL, New Albany IN, Louisville KY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07545759

Phase2, Recruiting

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

for
Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate,
Location: Springfield IL, St Louis MO, Des Plaines IL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07415044

Phase2, Recruiting

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

for
Arthritis, Psoriatic
Location: Springfield IL, Jonesboro AR, Jackson TN, Memphis TN,
Sponsor: MoonLake Immunotherapeutics AG

Sex: All

Age: 18+

Code: NCT06641089

Phase3, Recruiting

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

for
Breast Cancer, Metastatic Breast Cancer, Breast Neoplasm,
Location: Springfield IL, Urbana IL, Dyer IN, Chicago IL,
Sponsor: BriaCell Therapeutics Corporation

Sex: All

Age: 18+

Code: NCT06072612

Phase3, Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

for
Focal Onset Seizures
Location: Springfield IL, Nashville TN, Columbus OH,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT05716100

Phase3, Recruiting

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

for
Primary Generalized Tonic-Clonic Seizures
Location: Springfield IL, St Louis MO, Milwaukee WI,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 12+

Code: NCT05667142

Phase3, Recruiting

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for
Refractory Angina
Location: Springfield IL, Munster IN, Chicago IL, Carmel IN,
Sponsor: Shockwave Medical, Inc.

Sex: All

Age: 18+

Code: NCT05102019

Recruiting