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Paid Clinical Trials Springfield

Discover 203 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for
B Acute Lymphoblastic Leukemia
Location: Springfield IL, Peoria IL, St Louis MO, Iowa City IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 46

Code: NCT06124157

Phase 2, Recruiting

Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

for
Chronic Rhinosinusitis Without Nasal Polyps
Location: Springfield IL, Columbia MO, Louisville KY, Tulsa OK,
Sponsor: Optinose US Inc.

Sex: All

Age: 12 - 17

Code: NCT06850805

Phase 3, Recruiting

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Springfield IL, Chicago IL, Indianapolis IN,
Sponsor: Children's Oncology Group

Sex: All

Age: 15 - 20

Code: NCT06410209

Phase 2, Recruiting

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for
Low Grade Astrocytoma, Low Grade Glioma,
Location: Springfield IL, Peoria IL, St Louis MO, Iowa City IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2 - 21

Code: NCT04166409

Phase 3, Recruiting

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for
Embryonal Rhabdomyosarcoma,
Location: Springfield IL, Peoria IL, St Louis MO, Iowa City IA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT05304585

Phase 3, Recruiting

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UT-15C SR in the Treatment of Critical Limb Ischemia

for
Critical Limb Ischemia
Location: Springfield IL, Tucson AZ
Sponsor: Southern Arizona Vascular Institute

Sex: All

Age: 45 - 70+

Code: NCT00445159

Phase 2, Recruiting

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for
Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor,
Location: Springfield IL, Peoria IL, St Louis MO, Columbia MO,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 30

Code: NCT04322318

Phase 2, Recruiting

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for
Childhood Medulloblastoma
Location: Springfield IL, Peoria IL, St Louis MO, Iowa City IA,
Sponsor: Children's Oncology Group

Sex: All

Age: 4 - 21

Code: NCT05382338

Phase 3, Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Springfield IL, Peoria IL, St Louis MO, Columbia MO,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 22

Code: NCT04726241

Phase 1, Phase 2, Recruiting

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Location: Springfield IL, Decatur IL, Peoria IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 5 - 60

Code: NCT05675410

Phase 3, Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for
Ganglioneuroblastoma, Nodular, Neuroblastoma
Location: Springfield IL, Peoria IL, St Louis MO, Columbia MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 30

Code: NCT06172296

Phase 3, Recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for
Acute Myeloid Leukemia
Location: Springfield IL, Peoria IL, St Louis MO, Iowa City IA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT04293562

Phase 3, Recruiting

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for
Acute Leukemia of Ambiguous Lineage,
Location: Springfield IL, Peoria IL, St Louis MO, Oak Lawn IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 1

Code: NCT06317662

Phase 2, Recruiting

Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for
Acute Coronary Syndrome
Location: Springfield IL, St Louis MO, Davenport IA, Munster IN,
Sponsor: DalCor Pharmaceuticals

Sex: All

Age: 45+

Code: NCT05918861

Phase 3, Recruiting

Tissue Repair Gel in Venous Leg Ulcers (US)

for
Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer,
Location: Springfield IL, O'Fallon IL, Chicago IL, Tulsa OK,
Sponsor: TR Therapeutics

Sex: All

Age: 18+

Code: NCT06707090

Phase 3, Recruiting

Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers

for
Diabetic Foot Ulcer, Wagner Grade 1 - 2, Chronic Wound,
Location: Springfield IL, O'Fallon IL, Oradell NJ, McAllen TX
Sponsor: Eluciderm Inc

Sex: All

Age: 18 - 70+

Code: NCT07396376

Phase 1, Phase 2, Recruiting

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for
Solid Tumors
Location: Springfield IL, Naperville IL, Evanston IL, Madison WI,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT07522073

Phase 3, Recruiting

Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

for
Hypertriglyceridemia
Location: Springfield IL, St Louis MO, Memphis TN, Sarnia,
Sponsor: Marea Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07028749

Phase 2, Recruiting

Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

for
Graves Disease
Location: Springfield IL, Champaign IL, St Louis MO,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18 - 70

Code: NCT07661056

Phase 3, Recruiting

Study of Olverembatinib (HQP1351) in Patients With CML-CP

for
Chronic Myeloid Leukemia, CML, CML, Chronic Phase
Location: Decatur IL, St Louis MO, Chicago IL, Indianapolis IN,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18+

Code: NCT06423911

Phase 3, Recruiting