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Paid Clinical Trials Springfield

Discover 192 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Location: Springfield IL, Decatur IL, Peoria IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 5 - 60

Code: NCT05675410

Phase3, Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for
Ganglioneuroblastoma, Nodular, Neuroblastoma
Location: Springfield IL, Peoria IL, St Louis MO, Columbia MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 30

Code: NCT06172296

Phase3, Recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for
Acute Myeloid Leukemia
Location: Springfield IL, Peoria IL, St Louis MO, Iowa City IA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT04293562

Phase3, Recruiting

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for
Acute Leukemia of Ambiguous Lineage,
Location: Springfield IL, Peoria IL, St Louis MO, Oak Lawn IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 1

Code: NCT06317662

Phase2, Recruiting

Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for
Acute Coronary Syndrome
Location: Springfield IL, St Louis MO, Davenport IA, Munster IN,
Sponsor: DalCor Pharmaceuticals

Sex: All

Age: 45+

Code: NCT05918861

Phase3, Recruiting

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Tissue Repair Gel in Venous Leg Ulcers (US)

for
Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer,
Location: Springfield IL, O'Fallon IL, Chicago IL, Tulsa OK,
Sponsor: TR Therapeutics

Sex: All

Age: 18+

Code: NCT06707090

Phase3, Recruiting

Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers

for
Diabetic Foot Ulcer, Wagner Grade 1 - 2, Chronic Wound,
Location: Springfield IL, O'Fallon IL, Oradell NJ, McAllen TX
Sponsor: Eluciderm Inc

Sex: All

Age: 18 - 70+

Code: NCT07396376

Phase1, Phase2, Recruiting

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for
Solid Tumors
Location: Springfield IL, Naperville IL, Madison WI, Nashville TN,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT07522073

Phase3, Recruiting

Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

for
Hypertriglyceridemia
Location: Springfield IL, St Louis MO, Memphis TN, Sarnia,
Sponsor: Marea Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07028749

Phase2, Recruiting

Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

for
Graves Disease
Location: Springfield IL, Champaign IL, Lenexa KS, Memphis TN,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18 - 70

Code: NCT07661056

Phase3, Recruiting
New

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: Decatur IL, Alton IL, O'Fallon IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase3, Recruiting

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Decatur IL, O'Fallon IL, St Louis MO, Mount Vernon IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT07200830

Phase3, Recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Decatur IL, Alton IL, Effingham IL, O'Fallon IL,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06686771

Phase3, Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for
Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma
Location: Decatur IL, O'Fallon IL, New Lenox IL, Hinsdale IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06989437

Phase2, Phase3, Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for
Breast Neoplasms
Location: Decatur IL, Kansas City MO, Detroit MI, Maple Grove MN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06926868

Phase2, Phase3, Recruiting

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for
Cardiotoxicity, HER2/Neu Positive,
Location: Decatur IL, O'Fallon IL, St Louis MO, Ballwin MO,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT03418961

Phase3, Recruiting

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for
Castration Levels of Testosterone,
Location: Decatur IL, Pekin IL, Canton IL, Bloomington IL,
Sponsor: SWOG Cancer Research Network

Sex: Male

Age: 18+

Code: NCT03678025

Phase3, Recruiting

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Decatur IL, St Louis MO, Mount Vernon IL, Rolla MO,
Sponsor: National Cancer Institute LAO

Sex: All

Age: 0+

Code: NCT02474160

Recruiting

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for
Brain Metastases
Location: Decatur IL, Peoria IL, Urbana IL, O'Fallon IL,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT03550391

Phase3, Recruiting

Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling

for
HER2-negative Breast Cancer
Location: Decatur IL, Naperville IL, Iowa City IA, Louisville KY,
Sponsor: NSABP Foundation Inc

Sex: Female

Age: 18+

Code: NCT03412643

Phase2, Recruiting