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Paid Clinical Trials Springfield

Discover 192 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for
Lung Cancer Diagnosis
Location: Springfield IL, Chicago IL, Deerfield IL, Milwaukee WI,
Sponsor: Freenome Holdings Inc.

Sex: All

Age: 50+

Code: NCT06122077

Recruiting
Active & Responsive

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer

for
Advanced Breast Cancer, Early Breast Cancer
Location: Springfield IL, Lisle IL, Skokie IL, Evanston IL,
Sponsor: TerSera Therapeutics LLC

Sex: Female

Age: 18 - 55

Code: NCT07310420

Phase1, Recruiting
Active & Responsive

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for
Treatment Resistant Depression
Location: Springfield IL, St Louis MO, O'Fallon MO, Columbia MO,
Sponsor: LivaNova

Sex: All

Age: 18+

Code: NCT03887715

Recruiting
Active & ResponsiveNew

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Decatur IL, Pekin IL, Canton IL, Bloomington IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07441681

Phase3, Recruiting
Active & Responsive

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

for
Lung Non-Small Cell Carcinoma
Location: Decatur IL, Pekin IL, Canton IL, Bloomington IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07293247

Phase2, Recruiting

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Active & ResponsiveNew

The Effects of the Melillo Method® on Biopsychosocial Outcomes in School-Age Children

for
Social Behavior Disorders, Neurodevelopmental Disorders
Location: Roodhouse IL
Sponsor: Life University

Sex: All

Age: 8+

Code: NCT07779889

Recruiting
Active & Responsive

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for
Intestinal Neoplasms, Gastrointestinal Neoplasms,
Location: Pekin IL, Bloomington IL, Washington IL, Peoria IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222800

Phase3, Recruiting

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

for
Obesity, Overweight
Location: Springfield IL, Chattanooga TN, Cullman AL,
Sponsor: Kailera

Sex: All

Age: 18+

Code: NCT07284875

Phase3, Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06058377

Phase3, Recruiting

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for
Fallopian Tube Endometrioid Adenocarcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06580314

Phase3, Recruiting

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

for
Peripheral Vascular Diseases
Location: Springfield IL, Chicago IL, Indianapolis IN,
Sponsor: Boston Scientific Corporation

Sex: All

Age: 18+

Code: NCT04674969

Recruiting

Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for
Atrial Fibrillation (AF), Persistant Atrial Fibrillation,
Location: Springfield IL, Overland Park KS, Jonesboro AR,
Sponsor: Arga Medtech SA

Sex: All

Age: 18 - 70+

Code: NCT06784466

Recruiting

Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

for
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation,
Location: Springfield IL, Columbia MO, Naperville IL,
Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All

Age: 18+

Code: NCT04088071

Recruiting

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

for
Multiple Myeloma
Location: Springfield IL, Chicago IL, Glenview IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06152575

Phase3, Recruiting

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for
Childhood Extracranial Germ Cell Tumor,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Children's Oncology Group

Sex: All

Age: 0+

Code: NCT03067181

Phase3, Recruiting

Project: Every Child for Younger Patients With Cancer

for
Adrenal Gland Pheochromocytoma, Carcinoma In Situ,
Location: Springfield IL, Normal IL, Peoria IL, Effingham IL,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT02402244

Recruiting

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Springfield IL, Normal IL, Alton IL,
Sponsor: Children's Oncology Group

Sex: Female

Age: 0 - 39

Code: NCT06513962

Phase3, Recruiting

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for
Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)
Location: Springfield IL, St Louis MO, Lemont IL, Oak Park IL,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 50 - 70+

Code: NCT06541704

Phase3, Recruiting

Collection of Samples USOPTIVAL Study

for
Colorectal Cancer (CRC), Advanced Adenomas (AA)
Location: Springfield IL, Philadelphia PA, New Windsor NY,
Sponsor: Universal Diagnostics

Sex: All

Age: 45 - 70+

Code: NCT04792684

Recruiting

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for
Myelodysplastic Syndrome
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06577441

Phase2, Recruiting