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Paid Clinical Trials Springfield

Discover 192 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

for
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Location: Springfield IL, Dyer KY, Hinsdale IL, Muncie IN,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT06801834

Phase3, Recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for
Non-Muscle Invasive Bladder Urothelial Carcinoma,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06770582

Phase2, Recruiting

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for
Advanced Colorectal Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT06073431

Recruiting

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 60+

Code: NCT07437950

Phase2, Recruiting

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for
Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT05256225

Phase3, Recruiting

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Family Communications After Genetic Testing

for
Colon Adenocarcinoma, Colorectal Adenocarcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07143487

Recruiting

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07391774

Phase3, Recruiting

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

for
Metastatic Colorectal Cancer
Location: Springfield IL, Peoria IL, Columbia MO,
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18+

Code: NCT07549412

Phase3, Recruiting

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

for
Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia
Location: Springfield IL, Decatur IL, Effingham IL, Mattoon IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04840602

Phase2, Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for
Carcinoma, Non-Small-Cell Lung
Location: Springfield IL, Dyer IN, Arlington Heights IL,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06875310

Phase3, Recruiting

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06998940

Phase3, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07097142

Phase3, Recruiting

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for
Locally Advanced Urothelial Carcinoma,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06524544

Phase3, Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06876714

Phase3, Recruiting

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for
Castration-Sensitive Prostate Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT06931340

Phase3, Recruiting

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Springfield IL, Decatur IL, Peoria IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase3, Recruiting

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

for
Lung Non-Small Cell Carcinoma
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07388524

Phase3, Recruiting

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 65+

Code: NCT07321652

Phase3, Recruiting

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06958328

Phase3, Recruiting

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07061964

Phase2, Recruiting