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Paid Clinical Trials Springfield

Discover 203 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

for
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation,
Location: Springfield IL, Columbia MO, Naperville IL,
Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All

Age: 18+

Code: NCT04088071

Recruiting

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

for
Multiple Myeloma
Location: Springfield IL, Chicago IL, Glenview IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06152575

Phase 3, Recruiting

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for
Childhood Extracranial Germ Cell Tumor,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Children's Oncology Group

Sex: All

Age: 0+

Code: NCT03067181

Phase 3, Recruiting

Project: Every Child for Younger Patients With Cancer

for
Adrenal Gland Pheochromocytoma, Carcinoma In Situ,
Location: Springfield IL, Normal IL, Peoria IL, Effingham IL,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT02402244

Recruiting

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Springfield IL, Normal IL, Alton IL,
Sponsor: Children's Oncology Group

Sex: Female

Age: 0 - 39

Code: NCT06513962

Phase 3, Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for
Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)
Location: Springfield IL, St Louis MO, Lemont IL, Oak Park IL,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 50 - 70+

Code: NCT06541704

Phase 3, Recruiting
New

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

for
Richter Syndrome,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07220187

Phase 3, Recruiting
New

Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07393555

Phase 2, Recruiting
New

Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07578116

Phase 3, Recruiting

Collection of Samples USOPTIVAL Study

for
Colorectal Cancer (CRC), Advanced Adenomas (AA)
Location: Springfield IL, Philadelphia PA, New Windsor NY,
Sponsor: Universal Diagnostics

Sex: All

Age: 45 - 70+

Code: NCT04792684

Recruiting

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for
Myelodysplastic Syndrome
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06577441

Phase 2, Recruiting

Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

for
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Location: Springfield IL, Dyer KY, Hinsdale IL, Muncie IN,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT06801834

Phase 3, Recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for
Non-Muscle Invasive Bladder Urothelial Carcinoma,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06770582

Phase 2, Recruiting

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for
Advanced Colorectal Carcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT06073431

Recruiting

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

for
Advanced Extrapulmonary Neuroendocrine Carcinoma,
Location: Springfield IL, Decatur IL, Normal IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05058651

Phase 2, Phase 3, Recruiting

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 60+

Code: NCT07437950

Phase 2, Recruiting

Family Communications After Genetic Testing

for
Colon Adenocarcinoma, Colorectal Adenocarcinoma,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07143487

Recruiting

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Springfield IL, Decatur IL, Pekin IL, Canton IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07391774

Phase 3, Recruiting

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

for
Metastatic Colorectal Cancer
Location: Springfield IL, Peoria IL, Columbia MO,
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18+

Code: NCT07549412

Phase 3, Recruiting

A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia (ExCIT)

for
Patients With Chemotherapy-Induced Thrombocytopenia
Location: Springfield IL, Iowa City IA, Lincoln NE,
Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Sex: All

Age: 18+

Code: NCT07286032

Phase 3, Recruiting