Background illustration for clinical trials search

Paid Clinical Trials Springfield

Discover 203 paid clinical trials in Springfield, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

Filter
2
New

Testing Short-Course Radiation Versus Standard-Course Radiation for Soft Tissue Sarcomas That Need Surgery and Radiation

for
Recurrent Soft Tissue Sarcoma of the Trunk and Extremities,
Location: Decatur IL, Oak Creek WI, New Berlin WI, Milwaukee WI,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07615049

Phase 3, Recruiting

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: Decatur IL, Alton IL, O'Fallon IL,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase 3, Recruiting

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Decatur IL, O'Fallon IL, St Louis MO, Mount Vernon IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT07200830

Phase 3, Recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Decatur IL, Alton IL, Effingham IL, O'Fallon IL,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06686771

Phase 3, Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for
Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma
Location: Decatur IL, O'Fallon IL, New Lenox IL, Hinsdale IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06989437

Phase 2, Phase 3, Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for
Breast Neoplasms
Location: Decatur IL, Kansas City MO, Detroit MI, Maple Grove MN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06926868

Phase 2, Phase 3, Recruiting

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for
Cardiotoxicity, HER2/Neu Positive,
Location: Decatur IL, O'Fallon IL, St Louis MO, Ballwin MO,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT03418961

Phase 3, Recruiting

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for
Castration Levels of Testosterone,
Location: Decatur IL, Pekin IL, Canton IL, Bloomington IL,
Sponsor: SWOG Cancer Research Network

Sex: Male

Age: 18+

Code: NCT03678025

Phase 3, Recruiting

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for
Brain Metastases
Location: Decatur IL, Peoria IL, Urbana IL, O'Fallon IL,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT03550391

Phase 3, Recruiting

Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling

for
HER2-negative Breast Cancer
Location: Decatur IL, Naperville IL, Iowa City IA, Louisville KY,
Sponsor: NSABP Foundation Inc

Sex: Female

Age: 18+

Code: NCT03412643

Phase 2, Recruiting

Vitamin D for Prostate Endocrine Therapy

for
Stage I Prostate Cancer AJCC v8,
Location: Decatur IL, Effingham IL, Mattoon IL, Urbana IL,
Sponsor: University of Rochester

Sex: Male

Age: 50+

Code: NCT05838716

Phase 3, Recruiting

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

for
Head and Neck Squamous Cell Carcinoma
Location: Decatur IL, Peoria IL, St Louis MO, Chicago IL,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT06163534

Recruiting

GEMINI-NSCLC: NSCLC Biomarker Study

for
Non-Small Cell Lung Cancer
Location: Decatur IL, St Louis MO, Carterville IL, Iowa City IA,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05236114

Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Decatur IL, Peoria IL, St Louis MO, Chicago IL,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06667076

Phase 2, Recruiting

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative,
Location: Decatur IL, Peoria IL, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03739814

Phase 2, Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

for
Breast Neoplasms
Location: Decatur IL, Urbana IL, O'Fallon IL, Louisville KY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07173751

Phase 3, Recruiting

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Decatur IL, Chicago IL, Zion IL, Louisville KY,
Sponsor: Amgen

Sex: Male

Age: 18+

Code: NCT07213674

Phase 3, Recruiting

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

for
Metastatic Castration Sensitive Prostate Cancer (mCSPC),
Location: Decatur IL, O'Fallon IL, Chicago Ridge IL, Madison WI,
Sponsor: Pfizer

Sex: Male

Age: 18+

Code: NCT07028853

Phase 3, Recruiting

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Location: Decatur IL, Lexington KY, Rochester MN, Columbus OH,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07063745

Phase 2, Phase 3, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Decatur IL, Bridgeton MO, Quincy IL, Hinsdale IL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06692738

Phase 3, Recruiting