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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Burlington MA, East Greenwich RI, Framingham MA,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase3, Recruiting
Active & ResponsiveNew

Daily Upgrade Trial

for
Healthy Women
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: Female

Age: 25 - 45

Code: NCT07792603

Recruiting
Active & Responsive

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

for
Lactating Women on Select DOI,
Location: Durham NC, Pittsburgh PA, Chicago IL, Minneapolis MN,
Sponsor: Duke University

Sex: All

Age: 0+

Code: NCT03511118

Recruiting
Active & Responsive

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

for
Relapsed/Refractory Multiple Myeloma
Location: New York NY, Hackensack NJ, Richmond VA, Durham NC,
Sponsor: Caribou Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05722418

Phase1, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: Rimouski, Boston MA, New Haven CT, Quebec,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase3, Recruiting

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Active & Responsive

A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old

for
Graves' Disease
Location: Doral FL, Miami FL, Asheville NC, Dallas TX,
Sponsor: Biogen

Sex: All

Age: 18 - 70+

Code: NCT07722546

Phase2, Recruiting
Active & Responsive

IAP-086-1: A Phase 1 Single Ascending Dose First-Time in Human Study

for
HIV-1-infection
Location: Durham NC, Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 70

Code: NCT07596888

Phase1, Recruiting
Active & Responsive

Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in Ambulatory Participants With Duchenne Muscular Dystrophy (FORZETTO)

for
Duchenne Muscular Dystrophy (DMD), Muscular Dystrophy, Duchenne,
Location: Hillsborough NC
Sponsor: Dyne Therapeutics

Sex: Male

Age: 4 - 18

Code: NCT07608432

Phase3, Recruiting
Active & Responsive

Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)

for
Chronic Ankle Instability
Location: Fort Bragg NC, Lexington KY
Sponsor: Womack Army Medical Center

Sex: All

Age: 18 - 44

Code: NCT06527287

Recruiting
Active & Responsive

Siemens Biomarker Multi-modality

for
Fatty Liver, Hepatic Steatosis
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07495332

Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: Brewer ME, Scarborough ME, Boston MA, Providence RI,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase3, Recruiting
Active & Responsive

Royal Ancient Oats™ Study

for
Healthy Participants, Healthy Glucose
Location: Kannapolis NC
Sponsor: Standard Process Inc.

Sex: All

Age: 35 - 65

Code: NCT07371598

Recruiting
Active & Responsive

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for
Intestinal Neoplasms, Gastrointestinal Neoplasms,
Location: Topsham ME, Westbrook ME, Boston MA, Newton MA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222800

Phase3, Recruiting
Active & Responsive

REVerse Intestinal Metaplasia in the Stomach (REVISE)

for
Gastric Intestinal Metaplasia, Gastric Precancer
Location: Durham NC
Sponsor: Katherine Garman

Sex: All

Age: 18+

Code: NCT06590454

Phase2, Recruiting
Active & Responsive

BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System

for
Leadless Pacemaker, Bradycardia, AV Block,
Location: New York NY, Philadelphia PA, Paoli PA, Raleigh NC,
Sponsor: Biotronik, Inc.

Sex: All

Age: 18+

Code: NCT07118358

Recruiting
Active & Responsive

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: New York NY, Belleville NJ, Philadelphia PA, Newark DE,
Sponsor: Immuneering Corporation

Sex: All

Age: 18+

Code: NCT07562152

Phase3, Recruiting
Active & Responsive

Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans

for
Military Transition, Community Reintegration, Mental Health,
Location: Durham NC
Sponsor: RTI International

Sex: All

Age: 18+

Code: NCT06778278

Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

for
Alzheimer's Disease
Location: Halifax, East Providence RI, Newton MA, Quebec,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 60 - 70+

Code: NCT06976216

Phase3, Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Boston MA, Waterford CT, Guilford CT, New Haven CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase3, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Westerly RI, Waterford CT, Guilford CT, Glastonbury CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase2, Phase3, Recruiting

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