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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for
Alzheimer Disease
Location: North Dartmouth MA, Boston MA, Belmont MA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT06585787

Phase3, Recruiting
Active & Responsive

Belimumab With Rituximab for Primary Membranous Nephropathy

for
Membranous Nephropathy, Nephrotic Syndrome
Location: New York NY, Philadelphia PA, Baltimore MD, Bethesda MD,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 70+

Code: NCT03949855

Phase2, Recruiting
Active & Responsive

Intraoperative OCT Guidance of Intraocular Surgery II

for
Macular Holes, Epiretinal Membrane, Diabetic Retinopathy,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0+

Code: NCT03713268

Recruiting
Active & Responsive

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

for
Cancer, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: Alterome Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06835569

Phase1, Recruiting
Active & Responsive

Retinal Imaging in Neurodegenerative Disease

for
Alzheimer's Disease, Mild Cognitive Impairment,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT03233646

Recruiting

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Active & Responsive

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for
Sickle Cell Disease
Location: The Bronx NY, Philadelphia PA, Easton PA, Baltimore MD,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 70+

Code: NCT06439082

Phase3, Recruiting
Active & Responsive

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

for
Type 1 Diabetes Mellitus, T1D, T1DM,
Location: Boston MA, New York NY, Baltimore MD, Greenville NC,
Sponsor: COUR Pharmaceutical Development Company, Inc.

Sex: All

Age: 12 - 35

Code: NCT06783309

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

for
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP),
Location: New York NY, Raleigh NC, Durham NC, Chapel Hill NC,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06747351

Phase3, Recruiting
Active & Responsive

Opioids, Low Nicotine Cigarettes, and Chronic Pain

for
Chronic Pain, Tobacco Use, Opioid Substitution Treatment
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 21+

Code: NCT06747871

Recruiting
Active & Responsive

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for
Platinum-resistant Ovarian Cancer,
Location: Stony Brook NY, Greenville NC, Silver Spring MD,
Sponsor: Genelux Corporation

Sex: Female

Age: 18+

Code: NCT05281471

Phase3, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

for
Diabetic Peripheral Neuropathic Pain
Location: Boston MA, East Greenwich RI, Waterbury CT, Brooklyn NY,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 18 - 70+

Code: NCT07231419

Phase3, Recruiting
Active & Responsive

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for
Healthy
Location: Halifax, Boston MA, Quebec, Garden City NY, Mineola NY,
Sponsor: Pfizer

Sex: All

Age: 0 - 49

Code: NCT07160244

Phase3, Recruiting
Active & Responsive

Neurostimulation Versus Therapy for Problems With Emotions

for
Emotion Regulation, Mood Disorders, Stress Disorder,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 55

Code: NCT05712057

Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

for
Moderate to Severe Chronic Obstructive Pulmonary Disease
Location: Greenacres City FL, Loxahatchee Groves FL, Miami FL,
Sponsor: Pfizer

Sex: All

Age: 35 - 70+

Code: NCT07363694

Phase2, Phase3, Recruiting
Active & Responsive

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for
Obesity, Overweight
Location: East Greenwich RI, Waterbury CT, Newport News VA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07684235

Phase3, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for
Diabetic Peripheral Neuropathic Pain
Location: Boston MA, Waltham MA, East Greenwich RI, New York NY,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 18 - 70+

Code: NCT06628908

Phase3, Recruiting
Active & Responsive

A Self-compassion Focused Intervention for Internalized Weight Bias and Weight Loss

for
Overweight and Obesity
Location: Greenville NC
Sponsor: East Carolina University

Sex: All

Age: 18+

Code: NCT05987306

Recruiting
Active & Responsive

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

for
Percutaneous Coronary Intervention,
Location: Bangor ME, Lebanon NH, Stamford CT, Bridgeport CT,
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06909565

Recruiting
Active & Responsive

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for
Surgery-Complications, Anesthesia Complication,
Location: Boston MA, New Haven CT, Lebanon NH, New York NY,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05991453

Recruiting
Active & Responsive

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

for
Overweight, Obesity
Location: New Bedford MA, Needham MA, Stamford CT,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07589608

Phase2, Recruiting

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