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Paid Clinical Trials North Carolina

Discover 2,450 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Featured

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for
Multiple Myeloma
Location: New Haven CT, Washington D.C. DC, Winston-Salem NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07555938

Phase3, Recruiting
Featured

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

for
Obesity or Overweight, Type 2 Diabetes Mellitus
Location: Quebec, Sherbrooke, Montreal, Morehead City NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07351058

Phase3, Recruiting
Featured

A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for
Advanced Squamous Tumors
Location: Montreal, Toronto, Huntersville NC, Grand Rapids MI,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07241039

Phase1, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: Boston MA, New Haven CT, New York NY, Commack NY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase3, Recruiting
Featured

A Study to Assess the Safety and Efficacy of AGN-151586 Injections for the Treatment of Moderate to Severe Forehead Lines (FHL) in Adult Participants

for
Forehead Lines
Location: New York NY, Wilmington NC, Pflugerville TX,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07730554

Phase2, Recruiting

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Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Providence RI, New Haven CT, Lebanon NH, Bay Shore NY,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
Featured

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

for
Colorectal Cancer
Location: New Haven CT, Lake Success NY, East Brunswick NJ,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07525206

Phase3, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: Halifax, Boston MA, Watertown MA, Newton MA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: Rimouski, Boston MA, Worcester MA, Hartford CT, Quebec,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06793215

Phase3, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Boston MA, New Haven CT, New York NY, Chapel Hill NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06953960

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

for
Ulcerative Colitis
Location: London, Fresh Meadows NY, Montreal, Monroe NC,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT06979336

Phase2, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Boston MA, East Patchogue NY, The Bronx NY,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for
Atherosclerosis
Location: New Haven CT, North Massapequa NY, Chapel Hill NC,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07448038

Phase2, Recruiting
Featured

Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for
Ventral Hernia
Location: Hershey PA, Wilmington NC, Miami FL, Roanoke VA,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07226791

Phase2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Moncton, The Bronx NY, New York NY, East Brunswick NJ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting
Featured

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

for
Neovascular Age-related Macular Degeneration
Location: Hickory NC, Austin TX
Sponsor: Genentech, Inc.

Sex: All

Age: 50+

Code: NCT04853251

Recruiting
Featured

Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications

for
Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment,
Location: Morrisville NC
Sponsor: AbbVie

Sex: Female

Age: 0+

Code: NCT04846959

Recruiting
Featured

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for
Migraine
Location: Nashua NH, Stamford CT, Morristown NJ, Philadelphia PA,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05125302

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: Burlington MA, East Greenwich RI, Carmel NY,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase3, Recruiting
Featured

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

for
Episodic Migraine
Location: Morristown NJ, Philadelphia PA, Franklin VA, Miami FL,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05711394

Phase3, Recruiting

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