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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Charlotte NC, Winston-Salem NC, Wilson NC,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06667076

Phase2, Recruiting

Physician Engagement in EMS Transport Refusal Rates

for
Refusal of Transport
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT07107737

Recruiting

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

for
Ulcerative Colitis, Pediatric, Inflammatory Bowel Diseases,
Location: Charlotte NC, Chapel Hill NC, Durham NC, Pittsburgh PA
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 1 - 18

Code: NCT07198113

Recruiting

A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

for
Traumatic Brain Injury
Location: Charlotte NC, Cincinnati OH, Pittsburgh PA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07455136

Recruiting

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

for
Diabetes Mellitus Type 2, Childhood-Onset
Location: Charlotte NC, Winston-Salem NC, Cincinnati OH,
Sponsor: George Washington University

Sex: All

Age: 8 - 15

Code: NCT06525259

Recruiting

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J-Valve Transfemoral Pivotal Study

for
Aortic Valve Regurgitation, Aortic Valve Disease Mixed
Location: Charlotte NC, Atlanta GA, Washington D.C. DC,
Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC

Sex: All

Age: 18+

Code: NCT06455787

Recruiting

A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Cleveland OH,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18 - 70+

Code: NCT07149857

Phase2, Recruiting

Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

for
Cerebrovascular Disorders, Acute Cerebrovascular Disease
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18 - 70+

Code: NCT05871606

Phase1, Recruiting

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

for
Crohn Disease
Location: Charlotte NC, Chapel Hill NC, Lynchburg VA, Atlanta GA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07196722

Phase2, Phase3, Recruiting

A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During Surgery

for
Hemorrhage
Location: Charlotte NC, Washington D.C. DC, Louisville KY,
Sponsor: Corza Medical GmbH

Sex: All

Age: 0+

Code: NCT06664775

Phase3, Recruiting

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

for
Colitis, Ulcerative
Location: Charlotte NC, Chapel Hill NC, Lynchburg VA, Atlanta GA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 12+

Code: NCT07196748

Phase3, Recruiting

AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

for
Coronary Arterial Disease (CAD),
Location: Charlotte NC, Columbia SC, Charleston WV, Atlanta GA,
Sponsor: Boston Scientific Corporation

Sex: All

Age: 18+

Code: NCT06959524

Recruiting

Abbott Cephea Mitral Valve Disease Registry

for
Mitral Regurgitation, Mitral Stenosis, Mitral Valve Disease,
Location: Charlotte NC, Charleston SC, Atlanta GA, Norfolk VA,
Sponsor: Abbott Medical Devices

Sex: All

Age: 18+

Code: NCT07069673

Recruiting

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for
Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
Location: Charlotte NC, Kannapolis NC, Winston-Salem NC,
Sponsor: Duke University

Sex: All

Age: 70+

Code: NCT04262206

Recruiting

AltaValve Early Feasibility Study Protocol

for
Mitral Regurgitation, Mitral Insufficiency,
Location: Charlotte NC, Atlanta GA, Washington DC, Memphis TN,
Sponsor: 4C Medical Technologies, Inc.

Sex: All

Age: 18+

Code: NCT03997305

Recruiting

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2

for
Post Operative Surgical Site Infection
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: Major Extremity Trauma Research Consortium

Sex: All

Age: 18 - 64

Code: NCT04678154

Phase3, Recruiting

ATLAS (AltaValve) Pivotal Trial

for
Mitral Regurgitation, Mitral Insufficiency,
Location: Charlotte NC, Greenville NC, Atlanta GA,
Sponsor: 4C Medical Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06465745

Recruiting

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for
Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
Location: Charlotte NC, Durham NC, Atlanta GA, Fairfax VA,
Sponsor: Nuvalent Inc.

Sex: All

Age: 18+

Code: NCT06765109

Phase3, Recruiting

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

for
Aortic Dissection, Aortic Aneurysm, Intramural Hematoma,
Location: Charlotte NC, Chapel Hill NC, Roanoke VA, Charleston SC,
Sponsor: Endospan Ltd.

Sex: All

Age: 18+

Code: NCT04471909

Recruiting

US National OCS Heart Perfusion (OHP) Registry

for
Heart Transplant
Location: Charlotte NC, Chapel Hill NC, Durham NC, Charleston SC,
Sponsor: TransMedics

Sex: All

Age: 0+

Code: NCT05915299

Recruiting