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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for
High Risk Cardiovascular Disease, Hypertension,
Location: Statesville NC, Kings Mountain NC, Monroe NC,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07181109

Phase3, Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

for
Agitation, Alzheimer Disease
Location: Charlotte NC, Raleigh NC, Decatur GA, Savannah GA,
Sponsor: Celgene

Sex: All

Age: 55 - 70+

Code: NCT06808984

Phase2, Recruiting

A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors

for
Recurrent or Metastatic Solid Tumors
Location: Charlotte NC, Atlanta GA, Nashville TN, Maumee OH,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT07015697

Phase1, Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Charlotte NC, Gaffney SC, Union SC, Spartanburg SC,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06878261

Phase3, Recruiting

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

for
B-cell Non-Hodgkin Lymphoma, Follicular Lymphoma (FL),
Location: Charlotte NC, Nashville TN, Columbus OH, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06526793

Phase2, Recruiting

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A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

for
Psychotic Disorders, Alzheimer Disease
Location: Charlotte NC, Savannah GA, Maitland FL, Toms River NJ,
Sponsor: Intra-Cellular Therapies, Inc.

Sex: All

Age: 55+

Code: NCT06540833

Phase2, Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for
Heart Failure and Impaired Kidney Function
Location: Charlotte NC, Lancaster SC, Pinehurst NC, Asheville NC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06307652

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for
Polymyositis, Dermatomyositis
Location: Charlotte NC, Durham NC, Summerville SC, Charleston SC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06455449

Phase3, Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

for
Lupus Erythematosus, Systemic
Location: Charlotte NC, Chapel Hill NC, Atlanta GA, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70

Code: NCT06897930

Phase1, Phase2, Recruiting

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for
Endometrial Cancer
Location: Charlotte NC, Winston-Salem NC, Charleston SC,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06989112

Phase3, Recruiting

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for
Heart Failure
Location: Charlotte NC, Fort Mill SC, Monroe NC, Spartanburg SC,
Sponsor: AstraZeneca

Sex: All

Age: 40+

Code: NCT06677060

Phase3, Recruiting

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

for
End Stage Kidney Disease
Location: Charlotte NC, Shelby NC, Spartanburg SC, Columbia SC,
Sponsor: CSL Behring

Sex: All

Age: 18+

Code: NCT05485961

Phase2, Phase3, Recruiting

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

for
Asthma
Location: Charlotte NC, Rock Hill SC, High Point NC, Raleigh NC,
Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All

Age: 12+

Code: NCT06664619

Phase3, Recruiting

Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN

for
Lupus Nephritis
Location: Charlotte NC, Hixson TN, Columbus OH, Baltimore MD
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06527872

Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

for
Obstructive Hypertrophic Cardiomyopathy
Location: Charlotte NC, Greenville SC, Durham NC, Roanoke VA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT05489705

Recruiting

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for
Atrial Fibrillation (AF)
Location: Charlotte NC, Fort Mill SC, Statesville NC,
Sponsor: Anthos Therapeutics, Inc.

Sex: All

Age: 65+

Code: NCT05712200

Phase3, Recruiting

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for
Refractory Rheumatoid Arthritis (RA),
Location: Charlotte NC, Statesville NC, Roanoke VA, Charleston SC,
Sponsor: Artiva Biotherapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06991114

Phase2, Recruiting

A Pivotal Clinical Study to Evaluate the MySalvia System for the Treatment of Resistant Migraine

for
Resistant Migraine, Chronic Migraine Headache,
Location: Charlotte NC, Newnan GA, Olney MD
Sponsor: Salvia BioElectronics

Sex: All

Age: 22 - 70+

Code: NCT07719608

Recruiting

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

for
Psoriatic Arthritis
Location: Charlotte NC, Lawrenceville GA, Bowling Green KY,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06671496

Phase3, Recruiting

A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants

for
Gout
Location: Charlotte NC, Shelby NC, Atlanta GA, Lexington KY,
Sponsor: Crystalys Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07535034

Phase2, Recruiting