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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Charlotte NC, Goldsboro NC, Charlottesville VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136559

Phase3, Recruiting

Pan-tumor MRD Study

for
Muscle Invasive Bladder Urothelial Carcinoma, Esophageal Cancer,
Location: Charlotte NC, Goldsboro NC, Wilson NC, Corbin KY,
Sponsor: Paradigm Health

Sex: All

Age: 18+

Code: NCT06605404

Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

for
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms,
Location: Charlotte NC, Norfolk VA, Nashville TN, Pittsburgh PA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07218380

Phase3, Recruiting

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

for
Nausea, Vomiting,
Location: Charlotte NC, Huntersville NC, Savannah GA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07169851

Phase2, Recruiting

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for
Renal Cell Carcinoma
Location: Charlotte NC, Knoxville TN, Baltimore MD, Westbrook ME,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07227402

Phase3, Recruiting

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ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

for
Breast Neoplasms
Location: Charlotte NC, Midlothian VA, Richmond VA,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07173751

Phase3, Recruiting

Xeomin® and Gait Related Mobility After Stroke

for
Stroke
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18 - 70+

Code: NCT04908423

Recruiting

EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment

for
Ischemic Stroke
Location: Charlotte NC, Washington DC, Edison NJ, West Orange NJ,
Sponsor: BrainQ Technologies Ltd.

Sex: All

Age: 22 - 70+

Code: NCT06386874

Recruiting

Physical Therapy Wound Care Modalities in Patients With Spinal Cord Injury (SCI)

for
Spinal Cord Injuries, Pressure Injuries
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT05458947

Recruiting

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for
Chickenpox
Location: Charlotte NC, Simpsonville SC, Greenville SC,
Sponsor: GlaxoSmithKline

Sex: All

Age: 1

Code: NCT06740630

Phase3, Recruiting
New

A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)

for
Renal Insufficiency, Chronic
Location: Charlotte NC, Savannah GA, Louisville KY, Riverview FL,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07624305

Phase3, Recruiting

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Location: Charlotte NC, Winston-Salem NC, Norfolk VA, Fairfax VA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06129864

Phase3, Recruiting

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

for
Relapsed/Refractory Multiple Myeloma
Location: Charlotte NC, Durham NC, Atlanta GA, Charlottesville VA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05850234

Phase1, Phase2, Recruiting

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma,
Location: Charlotte NC, Columbus OH, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06564038

Phase1, Phase2, Recruiting

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

for
Major Depressive Disorder
Location: Charlotte NC, Atlanta GA, Savannah GA, Marietta GA,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT06775379

Phase3, Recruiting

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

for
B-cell Malignancies
Location: Charlotte NC, Winston-Salem NC, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06542250

Phase1, Phase2, Recruiting

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for
Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer,
Location: Charlotte NC, Pittsburgh PA, Baltimore MD, Commack NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05123482

Phase1, Phase2, Recruiting

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

for
Chronic Lymphocytic Leukemia (CLL),
Location: Charlotte NC, Winston-Salem NC, Durham NC, Boston MA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07024706

Phase2, Recruiting

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for
Gastric Cancer, Gastroesophageal Junction Adenocarcinoma,
Location: Charlotte NC, Winston-Salem NC, Blacksburg VA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07431281

Phase3, Recruiting

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

for
Transthyretin Amyloidosis With Cardiomyopathy
Location: Charlotte NC, Philadelphia PA, New Brunswick NJ,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07358078

Recruiting