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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

for
Non-obstructive Hypertrophic Cardiomyopathy
Location: Charlotte NC, Charlottesville VA, Richmond VA,
Sponsor: Imbria Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07023614

Phase2, Recruiting

A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

for
Ovarian Neoplasms, Breast Neoplasms
Location: Charlotte NC, Atlanta GA, Morristown NJ,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT04641247

Phase2, Recruiting

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

for
Multiple Myeloma, Newly Diagnosed Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Atlanta GA,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06679101

Phase3, Recruiting

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for
Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma,
Location: Charlotte NC, Raleigh NC, Augusta GA, Roanoke VA,
Sponsor: Sameek Roychowdhury

Sex: All

Age: 18+

Code: NCT06906562

Phase2, Recruiting

Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

for
Normal and Diseased Tissue and Body Fluids Samples
Location: Charlotte NC, Johnson City TN, Huntsville AL,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT01354002

Recruiting

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for
Hematologic Disorder, Bleeding Disorder,
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: American Thrombosis and Hemostasis Network

Sex: All

Age: 0+

Code: NCT04398628

Recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

for
T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma,
Location: Charlotte NC, Memphis TN, Tulsa OK, San Diego CA
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06390319

Phase2, Recruiting

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

for
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: Charlotte NC, Memphis TN, Tulsa OK
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06533748

Phase2, Recruiting

Sickle Cell Clinical Research and Intervention Program

for
Sickle Cell Disease
Location: Charlotte NC, Memphis TN, Peoria IL
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT02098863

Recruiting

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

for
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma,
Location: Charlotte NC, Memphis TN, Baton Rouge LA, Tulsa OK,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06289673

Recruiting

Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

for
Acute Pancreatitis
Location: Charlotte NC, Cincinnati OH, Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT04195347

Phase1, Phase2, Recruiting

Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US

for
Hypertension, Dyslipidemias, Type 2 Diabetes, HIV-1-infection
Location: Charlotte NC, Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05129345

Recruiting

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for
Ovarian Cancer
Location: Charlotte NC, Winston-Salem NC, Chattanooga TN,
Sponsor: Incyte Corporation

Sex: Female

Age: 18+

Code: NCT07214779

Phase3, Recruiting

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for
Refractory Angina
Location: Charlotte NC, Gainsville GA, Atlanta GA, Marietta GA,
Sponsor: Shockwave Medical, Inc.

Sex: All

Age: 18+

Code: NCT05102019

Recruiting

A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML)

for
AML, Adult
Location: Charlotte NC, Winston-Salem NC, Houston TX,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18 - 70+

Code: NCT04964518

Phase1, Phase2, Recruiting

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for
AL Amyloidosis
Location: Charlotte NC, Huntersville NC, Mooresville NC,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06022939

Phase3, Recruiting

Left vs Left Randomized Clinical Trial

for
Heart Failure, Heart Failure With Reduced Ejection Fraction,
Location: Charlotte NC, Asheville NC, Chapel Hill NC,
Sponsor: Baylor College of Medicine

Sex: All

Age: 18+

Code: NCT05650658

Recruiting

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Durham NC,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05552222

Phase3, Recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for
Stage I Mixed Cell Type Kidney Wilms Tumor,
Location: Charlotte NC, Winston-Salem NC, Columbia SC,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 30

Code: NCT06401330

Phase3, Recruiting

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for
Relapsed or Refractory T Cell Lymphoma
Location: Charlotte NC, Atlanta GA, Nashville TN, Cleveland OH,
Sponsor: Ono Pharmaceutical Co. Ltd

Sex: All

Age: 18+

Code: NCT05079282

Phase1, Recruiting