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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for
Advanced Lung Non-Squamous Non-Small Cell Carcinoma,
Location: Charlotte NC, Matthews NC, Huntersville NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04181060

Phase3, Recruiting

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for
Breast Cancer
Location: Charlotte NC, Spartanburg SC, Winston-Salem NC,
Sponsor: Exact Sciences Corporation

Sex: All

Age: 18+

Code: NCT06401421

Recruiting

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

for
Large B-cell Lymphoma
Location: Charlotte NC, Durham NC, Augusta GA, Charlottesville VA,
Sponsor: Allogene Therapeutics

Sex: All

Age: 18+

Code: NCT06500273

Phase2, Recruiting

Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

for
Relapsed or Refractory Large B-cell Lymphoma
Location: Charlotte NC, Newnan GA, Morgantown WV, Nashville TN,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18+

Code: NCT07479797

Phase3, Recruiting

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for
Melanoma
Location: Charlotte NC, Asheville NC, Durham NC, Roanoke VA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06246916

Phase3, Recruiting

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A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

for
Breast Neoplasms
Location: Charlotte NC, Winston-Salem NC, Lexington KY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07060807

Phase3, Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for
Triple Negative Breast Cancer
Location: Charlotte NC, Spartanburg SC, Winston-Salem NC,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT05633654

Phase3, Recruiting

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

for
Acute Myeloid Leukemia, in Relapse,
Location: Charlotte NC, Winston-Salem NC, Houston TX
Sponsor: ARCE Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06680752

Phase1, Phase2, Recruiting

A Study of Combination of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Subject With Previously Treated Multiple Myeloma

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Spartanburg SC,
Sponsor: Stichting European Myeloma Network

Sex: All

Age: 18+

Code: NCT05028348

Phase3, Recruiting

A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for
Cervical Cancer
Location: Charlotte NC, Statesville NC, Thomasville NC,
Sponsor: GOG Foundation

Sex: Female

Age: 18+

Code: NCT04831580

Recruiting

Remote Ischemic Conditioning Using the autoRIC

for
Ischemia-Reperfusion Injury
Location: Charlotte NC, Raleigh NC, Jacksonville FL,
Sponsor: CellAegis US, Inc.

Sex: All

Age: 18+

Code: NCT03318575

Recruiting

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for
Acute Myeloid Leukaemia (AML), Follicular Lymphoma ( FL)
Location: Charlotte NC, Bethesda MD, Cincinnati OH, Columbus OH,
Sponsor: Tempus AI

Sex: All

Age: 0+

Code: NCT07154823

Recruiting

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

for
Aortic Stenosis, Severe
Location: Charlotte NC, Norfolk VA, Cincinnati OH, Nashville TN,
Sponsor: Edwards Lifesciences

Sex: All

Age: 0+

Code: NCT05172960

Recruiting

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for
Cardiovascular Disease and Lipoprotein(a)
Location: Charlotte NC, Winston-Salem NC, Greensboro NC,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07517263

Phase3, Recruiting

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Location: Charlotte NC, Kingsport TN, Gainesville GA,
Sponsor: University of British Columbia

Sex: All

Age: 0+

Code: NCT04634240

Recruiting

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for
Aortic Valve Insufficiency, Aortic Valve Stenosis
Location: Charlotte NC, Atlanta GA, Cincinnati OH, Nashville TN,
Sponsor: Edwards Lifesciences

Sex: All

Age: 0+

Code: NCT05172973

Recruiting

Primary Subtalar Arthrodesis for Calcaneal Fractures

for
Calcaneus Fracture
Location: Charlotte NC, Concord NC, Greenville SC, Chapel Hill NC,
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06249126

Recruiting

Comparison of Urinary Flow Study

for
Urinary Retention
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: Female

Age: 18+

Code: NCT06918067

Recruiting

M-Vizion™ Macroscopic Radiographic Study

for
Revision Hip Arthroplasty
Location: Charlotte NC, Danville PA, Chicago IL, Boston MA,
Sponsor: Medacta USA

Sex: All

Age: 21 - 70+

Code: NCT05721859

Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

for
Elbow Joint Destruction, Post-traumatic Lesions,
Location: Charlotte NC, Philadelphia PA, Germantown TN, Golden CO
Sponsor: Zimmer Biomet

Sex: All

Age: 18+

Code: NCT02469662

Recruiting