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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for
Intracranial Aneurysm
Location: Charlotte NC, Greenville SC, Morgantown WV,
Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All

Age: 18 - 70+

Code: NCT02998229

Recruiting
Active & Responsive

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for
Obesity, Overweight
Location: Shelby NC, Louisville KY, Hickory NC, Greenville SC,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07684235

Phase3, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for
Major Depressive Disorder (MDD)
Location: Charlotte NC, Snellville GA, Cincinnati OH, Carmel IN,
Sponsor: Vanda Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT06830044

Phase3, Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

for
Asthma
Location: Charlotte NC, Huntersville NC, Gastonia NC,
Sponsor: Pfizer

Sex: All

Age: 18 - 70

Code: NCT06977581

Phase2, Recruiting
Active & Responsive

Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for
Lymphoid Leukemia
Location: Charlotte NC, Fairfax VA, Cincinnati OH, Baltimore MD,
Sponsor: Stanford University

Sex: All

Age: 0 - 26

Code: NCT05865301

Recruiting

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Active & Responsive

Caring Connections Youth Suicide Detection and Intervention Study

for
Suicide, Suicide Prevention, Suicide Ideation, Suicide Attempt
Location: Charlotte NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 13+

Code: NCT06353711

Recruiting
Active & Responsive

A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.

for
Malocclusion
Location: Huntersville NC, Frisco TX, Fresno CA
Sponsor: Dentsply Sirona Implants and Consumables

Sex: All

Age: 18+

Code: NCT07290790

Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

for
Alzheimer's Disease
Location: Matthews NC, Gainesville GA, Washington D.C. DC,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 60 - 70+

Code: NCT06976216

Phase3, Recruiting
Active & Responsive

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for
Alzheimer Disease
Location: Matthews NC, Greensboro NC, Atlanta GA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT06585787

Phase3, Recruiting
Active & Responsive

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

for
Capsular Contracture Associated With Breast Implant,
Location: Huntersville NC, Alpharetta GA, Atlanta GA,
Sponsor: C. R. Bard

Sex: Female

Age: 22 - 70

Code: NCT05945329

Recruiting
Active & Responsive

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

for
Chronic Kidney Diseases, End Stage Renal Disease,
Location: Charlotte NC, Spartanburg SC, Columbia SC,
Sponsor: VenoStent

Sex: All

Age: 18+

Code: NCT06001827

Recruiting
Active & Responsive

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for
Hypertension, Hypertension, Systolic, Hypertension, Essential
Location: Charlotte NC, Asheville NC, Raleigh NC, Lynchburg VA,
Sponsor: Orchestra BioMed, Inc

Sex: All

Age: 18+

Code: NCT06059638

Recruiting
Active & Responsive

Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

for
Migraine
Location: Charlotte NC, Salisbury NC, Winston-Salem NC,
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70

Code: NCT06972056

Recruiting
Active & Responsive

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

for
Coronavirus Disease (COVID-19)
Location: Charlotte NC, Monroe NC, Mount Airy NC,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06667700

Phase3, Recruiting
Active & Responsive

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients

for
Epilepsy, Healthy Volunteer
Location: Charlotte NC, Bathesda MD, DeLand FL,
Sponsor: Suninflam Inc

Sex: All

Age: 18 - 70

Code: NCT07051629

Phase1, Recruiting
Active & Responsive

Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden

for
Sjögren´s Disease
Location: Charlotte NC, Memphis TN, Jackson TN, Tampa FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07621809

Phase3, Recruiting
Active & Responsive

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Huntersville NC, Charleston SC, Louisville KY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06750185

Phase1, Phase2, Recruiting
Active & Responsive

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

for
Non Small Cell Lung Cancer, Pancreatic Ductal Adenocarcinoma
Location: Huntersville NC, Fairfax VA, Nashville TN,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05431270

Phase1, Phase2, Recruiting
Active & Responsive

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for
Solid Tumor Malignancies, Colorectal Carcinoma,
Location: Huntersville NC, Fairfax VA, Denver CO, Cleveland OH,
Sponsor: Tasca Therapeutics

Sex: All

Age: 18+

Code: NCT07030257

Phase1, Phase2, Recruiting
Active & Responsive

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

for
Triple Negative Breast Cancer, HER2-negative Breast Cancer,
Location: Huntersville NC, Greenville SC, Fairfax VA, Orlando FL,
Sponsor: Dren Bio

Sex: All

Age: 18+

Code: NCT06999187

Phase1, Recruiting