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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for
Multiple Myeloma, Myeloma, Myeloma Multiple
Location: Charlotte NC, Durham NC, Charleston SC, Atlanta GA,
Sponsor: K36 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05651932

Phase1, Recruiting

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

for
Multiple Myeloma, Cancer
Location: Charlotte NC, Chapel Hill NC, Durham NC, Wilmington NC,
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05145400

Phase2, Recruiting

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

for
Sickle Cell Disease
Location: Charlotte NC, Greenville NC, Birmingham AL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 55

Code: NCT06546670

Phase1, Phase2, Recruiting

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma,
Location: Charlotte NC, Charleston SC, Nashville TN,
Sponsor: Bicara Therapeutics

Sex: All

Age: 18+

Code: NCT04429542

Phase1, Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

for
Non-Small Cell Lung Cancer
Location: Charlotte NC, Greenville SC, Chapel Hill NC,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT05899608

Phase3, Recruiting

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Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

for
Estrogen Receptor Negative, HER2 Positive Breast Carcinoma,
Location: Charlotte NC, Jacksonville FL, Pittsburgh PA,
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 30+

Code: NCT02945579

Recruiting

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

for
Nonsmall Cell Lung Cancer, Performance Status
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT04253964

Phase2, Recruiting

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

for
Metastatic Prostate Cancer
Location: Charlotte NC, Fairfax VA, Silver Spring MD,
Sponsor: ORIC Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT05413421

Phase1, Recruiting

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

for
Ovarian Cancer, Ovarian Cancer Recurrent
Location: Charlotte NC, Augusta GA, Charlottesville VA,
Sponsor: Compugen Ltd

Sex: Female

Age: 18+

Code: NCT06888921

Phase1, Phase2, Recruiting

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

for
Acute Myeloid Leukemia,
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05886049

Phase1, Recruiting

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

for
Leukemia, Myeloid, Acute
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06580106

Recruiting

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

for
Lung Neoplasms, Lung Cancer
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 40 - 54

Code: NCT04577599

Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

for
Relapsed or Refractory Multiple Myeloma,
Location: Charlotte NC, Philadelphia PA, New York NY, Houston TX,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05652335

Phase1, Recruiting

Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery

for
Head and Neck Cancer,
Location: Charlotte NC, Winston-Salem NC, Milwaukee WI
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06607406

Recruiting

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

for
Endometrial Cancer, Endometrioid Tumor, Cancer, Tumor,
Location: Charlotte NC, New York NY, Little Rock AR,
Sponsor: Aadi Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05997017

Phase2, Recruiting

Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients

for
Pediatric Cancer
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 2 - 21

Code: NCT04948619

Phase2, Recruiting

Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study

for
Chronic Graft-versus-Host-Disease, Leukemia,
Location: Charlotte NC, Nashville TN, Columbus OH, New York NY,
Sponsor: University of British Columbia

Sex: All

Age: 0 - 24

Code: NCT04372524

Recruiting

Phase 1 Trial of BTM-3566 in Relapsed/Refractory Mature B Cell Lymphomas

for
Lymphoma, B-Cell
Location: Charlotte NC, Houston TX
Sponsor: Bantam Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06792734

Phase1, Recruiting

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

for
Advanced Solid Tumors Cancer, MSI-H Cancer
Location: Charlotte NC, Winston-Salem NC, Greenville SC,
Sponsor: Nimbus Wadjet, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06898450

Phase1, Phase2, Recruiting

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for
Relapsed or Refractory Multiple Myeloma (RRMM)
Location: Charlotte NC, Atlanta GA, Washington D.C. DC,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06615479

Phase3, Recruiting