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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions

for
Lumbar Spine Degeneration, Lumbar Spine Instability,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT04140344

Recruiting

RaDIANT Health Systems Intervention

for
End Stage Renal Disease (ESRD), Kidney Disease
Location: Durham NC, Lancaster SC, Atlanta GA, Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18 - 70+

Code: NCT07033117

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

for
Focal Onset Seizures
Location: Durham NC, Bethesda MD, Columbus OH, Cleveland OH,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT05716100

Phase3, Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

for
Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis,
Location: Durham NC, Chapel Hill NC, Bethesda MD, Frederick MD,
Sponsor: CSL Behring

Sex: All

Age: 18+

Code: NCT07332091

Phase2, Recruiting

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

for
Sickle Cell Disease
Location: Durham NC, Greenville NC, Clinton SC, Greer SC,
Sponsor: Pfizer

Sex: All

Age: 12+

Code: NCT05431088

Phase2, Phase3, Recruiting

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Allopregnanolone (Zuranolone) in Post-stroke Depression

for
Post Stroke Depression
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 21 - 65

Code: NCT06759558

Phase2, Recruiting

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

for
Parkinsons Disease (PD)
Location: Durham NC, Richmond VA, Washington D.C. DC,
Sponsor: BlueRock Therapeutics

Sex: All

Age: 45 - 70+

Code: NCT06944522

Phase3, Recruiting

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: Durham NC, Philadelphia PA, Atlanta GA, Columbus OH,
Sponsor: Syndax Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04065399

Phase1, Phase2, Recruiting

Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft

for
Ankle and Hindfoot Arthrodesis
Location: Durham NC, Charlotte NC, Falls Church VA, Baltimore MD,
Sponsor: BioMimetic Therapeutics

Sex: All

Age: 18+

Code: NCT02879149

Recruiting

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

for
Liver Transplant
Location: Durham NC, Pittsburgh PA, Philadelphia PA, New York NY,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18+

Code: NCT06280950

Phase2, Recruiting

Tocilizumab in Lung Transplantation

for
Lung Transplant
Location: Durham NC, Atlanta GA, Columbus OH, Cleveland OH,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 12 - 70+

Code: NCT06033196

Phase2, Recruiting

CAR-T Long Term Follow Up (LTFU) Study

for
Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program,
Location: Durham NC, Philadelphia PA, Atlanta GA, Columbus OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 0 - 70+

Code: NCT02445222

Phase3, Recruiting

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: OncoC4, Inc.

Sex: All

Age: 18+

Code: NCT06635785

Phase1, Phase2, Recruiting

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

for
Multiple Myeloma, Cancer
Location: Durham NC, Chapel Hill NC, Charlotte NC, Wilmington NC,
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05145400

Phase2, Recruiting

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for
Epithelial Ovarian Cancer, Primary Peritoneal,
Location: Durham NC, Norfolk VA, Annapolis MD, Philadelphia PA,
Sponsor: TORL Biotherapeutics, LLC

Sex: Female

Age: 18+

Code: NCT06690775

Phase2, Recruiting

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

for
Low Risk Myelodysplastic Syndromes
Location: Durham NC, Columbus OH, Cleveland OH, New York NY,
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT05308264

Phase1, Phase2, Recruiting

A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

for
Platinum-resistant Ovarian Cancer, Testicular Cancer,
Location: Durham NC, New York NY, Nashville TN, Providence RI,
Sponsor: Context Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06515613

Phase1, Recruiting

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for
Breast Cancer
Location: Durham NC, Greensboro NC, Fayetteville NC, Richmond VA,
Sponsor: Stemline Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06492616

Phase3, Recruiting

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor
Location: Durham NC, Fairfax VA, Philadelphia PA, Nashville TN,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06108050

Phase1, Recruiting

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for
Prostate Cancer,
Location: Durham NC, Charlottesville VA, Myrtle Beach SC,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male

Age: 18+

Code: NCT04729114

Phase1, Recruiting