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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Durham NC, Huntersville NC, Fairfax VA, Baltimore MD,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06040541

Phase1, Recruiting

CGX1321 in Subjects With Advanced Solid Tumors and CGX1321 With Pembrolizumab or Encorafenib + Cetuximab in Subjects With Advanced GI Tumors (Keynote 596)

for
Solid Tumors, GI Cancer
Location: Durham NC, Washington DC, Baltimore MD, Boston MA,
Sponsor: Curegenix Inc.

Sex: All

Age: 18+

Code: NCT02675946

Phase1, Recruiting

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma,
Location: Durham NC, Washington D.C. DC, Columbus OH,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 3 - 39

Code: NCT05096481

Phase2, Recruiting

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

for
Relapsed/Refractory Acute Myeloid Leukemia (AML),
Location: Durham NC, Atlanta GA, New York NY, Buffalo NY,
Sponsor: Cullinan Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT05143996

Phase1, Recruiting

The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

for
Solid Tumors
Location: Durham NC, Atlanta GA, Toronto, Boston MA, St Louis MO,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT05203172

Recruiting

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Efficacy Study of Inecalcitol With Decitabine in Acute Myeloid Leukemia Patients Unfit for Standard Chemotherapy

for
Acute Myelogenous Leukemia
Location: Durham NC, Augusta GA, Houston TX, Albuquerque NM,
Sponsor: Hybrigenics Corporation

Sex: All

Age: 65+

Code: NCT02802267

Phase2, Recruiting

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for
Stage III Ovarian Cancer, Stage IV Ovarian Cancer,
Location: Durham NC, Raleigh NC, Norfolk VA, Fairfax VA,
Sponsor: GOG Foundation

Sex: Female

Age: 18+

Code: NCT05659381

Phase3, Recruiting

Optimizing Surgical Decisions in Young Adults With Breast Cancer

for
Breast Cancer Stage 0, Breast Cancer Stage I,
Location: Durham NC, New York NY, New Haven CT, Boston MA
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 18 - 44

Code: NCT06275126

Recruiting

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

for
Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD),
Location: Durham NC, Charlotte NC, Washington D.C. DC,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 0+

Code: NCT03394365

Phase3, Recruiting

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

for
Liver Cancer
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT04933435

Recruiting

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

for
Melanoma Stage IIIB, Melanoma Stage IIIC, Melanoma Stage IIID
Location: Durham NC, Richmond VA, Hershey PA, Atlanta GA,
Sponsor: Philogen S.p.A.

Sex: All

Age: 18+

Code: NCT03567889

Phase3, Recruiting

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for
Prostate Cancer
Location: Durham NC, Chapel Hill NC, Charlottesville VA,
Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male

Age: 21+

Code: NCT03151629

Recruiting

A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

for
Metastatic HER2-positive Breast Cancer
Location: Durham NC, Morrisville NC, Roanoke VA, Norfolk VA,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06435429

Phase3, Recruiting

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

for
Brain Tumor, Primary, Brain Metastases, Adult
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05480644

Recruiting

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for
High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer,
Location: Durham NC, Chesapeake VA, Fairfax VA, Philadelphia PA,
Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female

Age: 18+

Code: NCT05128825

Phase2, Recruiting

REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors

for
Ovarian Cancer, Advanced Ovarian Carcinoma,
Location: Durham NC, Boston MA, Aurora CO, Boulder CO
Sponsor: Dana-Farber Cancer Institute

Sex: Female

Age: 18+

Code: NCT06710548

Recruiting

KM3D Multicenter Cancer Consortium: Predicting Patient Response Using 3D Cell Culture Models

for
Cancer, Predictive Cancer Model, Effects of Chemotherapy
Location: Durham NC, Rochester MN, Houston TX
Sponsor: Known Medicine, Inc.

Sex: All

Age: 18+

Code: NCT05338073

Recruiting

A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for
NSCLC (Advanced Non-small Cell Lung Cancer)
Location: Durham NC, Fairfax VA, Washington D.C. DC,
Sponsor: BlossomHill Therapeutics

Sex: All

Age: 18+

Code: NCT06706076

Phase1, Phase2, Recruiting

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for
Advanced Melanoma
Location: Durham NC, Chapel Hill NC, Washington D.C. DC,
Sponsor: Replimune, Inc.

Sex: All

Age: 12+

Code: NCT06264180

Phase3, Recruiting

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors

for
Hematopoietic Stem Cell Transplant
Location: Durham NC, Tampa FL, Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT06328127

Recruiting