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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Improving Outcomes in Early Menopause After Cancer

for
Early Menopause, Cancer, Premature Menopause,
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 18 - 44

Code: NCT06982677

Recruiting

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for
KRAS Altered Advanced or Metastatic Solid Tumors
Location: Durham NC, Fairfax VA, Philadelphia PA, Atlanta GA,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT07094113

Phase1, Recruiting

Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

for
Cancer, Youth Cancer, Young Adult Cancer,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 19 - 25

Code: NCT06732375

Recruiting

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

for
Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma,
Location: Durham NC, Fairfax VA, Atlanta GA, Hackensack NJ,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07488676

Phase1, Phase2, Recruiting

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

for
Carcinoma, Hepatocellular, Hepatocellular Cancer,
Location: Durham NC, Cary NC, Raleigh NC, Land O' Lakes FL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07227012

Phase1, Phase2, Recruiting

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A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for
Breast Neoplasms
Location: Durham NC, Midlothian VA, Greenville SC, Winchester VA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06926868

Phase2, Phase3, Recruiting

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

for
Cancer, Breast Cancer, Colorectal Cancer, Sarcoma, Lymphoma,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 39

Code: NCT06371768

Recruiting

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

for
Renal Cell Carcinoma
Location: Durham NC, Pittsburgh PA, New York NY, Mineola NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18 - 70+

Code: NCT07049926

Phase1, Phase2, Recruiting

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for
Low-grade NMIBC, FGFR Gene Amplification, FGFR Gene Alterations,
Location: Durham NC, Raleigh NC, Myrtle Beach SC,
Sponsor: Tyra Biosciences, Inc

Sex: All

Age: 18+

Code: NCT06995677

Phase2, Recruiting

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for
Myelofibrosis
Location: Durham NC, Charlottesville VA, Charleston SC,
Sponsor: Sumitomo Pharma America, Inc.

Sex: All

Age: 18+

Code: NCT04176198

Phase1, Phase2, Recruiting

Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy

for
Cytokine Release Syndrome
Location: Durham NC, Augusta GA, Pittsburgh PA, Boston MA,
Sponsor: CytoAgents, Inc.

Sex: All

Age: 18+

Code: NCT05905328

Phase1, Phase2, Recruiting

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

for
Advanced Solid Tumor, Advanced Breast Cancer,
Location: Durham NC, Columbus OH, Nashville TN, Denver CO,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06120283

Phase1, Recruiting

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

for
Gastric or Gastroesophageal Junction Adenocarcinoma,
Location: Durham NC, Fairfax VA, Pittsburgh PA, Louisville KY,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05482893

Phase1, Phase2, Recruiting

Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma

for
Solid Tumor, Soft Tissue Sarcoma, Metastatic Sarcoma, Sarcoma
Location: Durham NC, Chapel Hill NC, Santa Monica CA
Sponsor: NanoCarrier Co., Ltd.

Sex: All

Age: 18 - 70+

Code: NCT03168061

Phase1, Phase2, Recruiting

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for
Colorectal Neoplasms
Location: Durham NC, Pinehurst NC, Roanoke VA, Salem VA,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05253651

Phase3, Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for
Triple Negative Breast Cancer
Location: Durham NC, Chapel Hill NC, Greensboro NC,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT05633654

Phase3, Recruiting

Engage Psychosocial Intervention for Cancer Symptoms

for
Advanced Breast Cancer, Advanced Prostate Cancer,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06555588

Recruiting

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for
Relapsed Hematologic Malignancy,
Location: Durham NC, Pittsburgh PA, Cleveland OH, Jacksonville FL,
Sponsor: Curis, Inc.

Sex: All

Age: 18+

Code: NCT03328078

Phase1, Phase2, Recruiting

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for
Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
Location: Durham NC, Charlotte NC, Fairfax VA, Atlanta GA,
Sponsor: Nuvalent Inc.

Sex: All

Age: 18+

Code: NCT06765109

Phase3, Recruiting

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for
T-Cell Neoplasm, Lymphoproliferative Disorders
Location: Durham NC, Columbus OH, Ann Arbor MI, Duarte CA
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT04858256

Phase2, Recruiting