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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Phase 1/1b Study of IAM1363 in HER2 Cancers

for
HER2 Mutation-Related Tumors, HER2, HER2-positive Breast Cancer,
Location: Durham NC, Fairfax VA, New Brunswick NJ, Cleveland OH,
Sponsor: Iambic Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06253871

Phase1, Recruiting

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for
Solid Tumors
Location: Durham NC, Spartanburg SC, Fairfax VA,
Sponsor: ORIC Pharmaceuticals

Sex: All

Age: 18+

Code: NCT05315700

Phase1, Phase2, Recruiting

A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for
Low-grade Glioma, Advanced Solid Tumor
Location: Durham NC, Washington DC, Philadelphia PA, New York NY,
Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All

Age: 0 - 25

Code: NCT04775485

Phase2, Recruiting

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

for
Relapsed or Refractory Multiple Myeloma
Location: Durham NC, Roanoke VA, Norfolk VA, Fredericksburg VA,
Sponsor: Celgene

Sex: All

Age: 18+

Code: NCT05519085

Phase3, Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for
Metastatic Colorectal Cancer
Location: Durham NC, Pikeville KY, Jacksonville FL, Nashville TN,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT06252649

Phase3, Recruiting

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Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

for
Early Breast Cancer
Location: Durham NC, Greensboro NC, Midlothian VA, Norfolk VA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT05827081

Phase3, Recruiting

Safety of HRX215 in Patients After Minor and Major Liver Resection

for
Liver Resection, Colorectal Carcinoma Liver Metastases
Location: Durham NC, Baltimore MD, Cleveland OH, Rochester MN
Sponsor: HepaRegeniX GmbH

Sex: All

Age: 18 - 70+

Code: NCT06638502

Phase1, Phase2, Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Location: Durham NC, Chapel Hill NC, Richmond VA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06119581

Phase3, Recruiting

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

for
Hematopoietic Stem Cell Transplant, CAR-T Cell Therapy
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT06575712

Recruiting

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for
Solid Tumors, Hematologic Malignancies
Location: Durham NC, Chapel Hill NC, Cary NC, Roanoke VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT03486873

Phase3, Recruiting

A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for
Cervical Cancer
Location: Durham NC, Greensboro NC, Kernersville NC,
Sponsor: GOG Foundation

Sex: Female

Age: 18+

Code: NCT04831580

Recruiting

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

for
Breast Cancer, Breast Cancer Metastatic,
Location: Durham NC, Charlotte NC, Augusta GA, Atlanta GA,
Sponsor: Incyclix Bio

Sex: All

Age: 18+

Code: NCT05735080

Phase1, Phase2, Recruiting

A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

for
Extensive-Stage Small Cell Lung Cancer
Location: Durham NC, Roanoke VA, Marietta GA, Cincinnati OH,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06646276

Phase3, Recruiting
New

A Randomized Controlled Trial Testing a Digital, Gamified Early Intervention for Eating Disorders ("FlexED")

for
Eating Disorders, Body Image
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 15 - 25

Code: NCT07632248

Recruiting
New

Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children

for
Decision Making, Neonatal Critical Illness,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0+

Code: NCT07390773

Recruiting

Registry of Arthrex Hand and Wrist Products

for
Ulnar/Radial Collateral Ligament Reconstruction,
Location: Durham NC, Morgantown WV, Tuscon AZ, Phoenix AZ
Sponsor: Arthrex, Inc.

Sex: All

Age: 18+

Code: NCT05046600

Recruiting

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

for
Lung Transplant
Location: Durham NC, Baltimore MD, Philadelphia PA, Cincinnati OH,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 12+

Code: NCT06476132

Phase2, Recruiting

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

for
Glioblastoma Multiforme
Location: Durham NC, Los Angeles CA, Santa Monica CA,
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT05708352

Phase2, Recruiting

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

for
Neuroblastoma
Location: Durham NC, Charlotte NC, Richmond VA, Charleston SC,
Sponsor: Giselle Sholler

Sex: All

Age: 1 - 21

Code: NCT05489887

Phase2, Recruiting

Hyperpolarized 129Xe MRI Lung Health Cohort

for
Healthy
Location: Durham NC, Iowa City IA, Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 25 - 35

Code: NCT05766384

Recruiting