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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for
Embryonal Rhabdomyosarcoma,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT05304585

Phase3, Recruiting

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for
Ovarian Carcinoma
Location: Durham NC, Chapel Hill NC, Raleigh NC, Cary NC,
Sponsor: NRG Oncology

Sex: Female

Age: 35 - 50

Code: NCT04251052

Recruiting

Imaging Retinal Vasculature in Infant Eyes

for
Retinopathy of Prematurity
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0

Code: NCT05558059

Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Durham NC, Winston-Salem NC, Greenville NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06317649

Phase2, Recruiting

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for
Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor,
Location: Durham NC, Winston-Salem NC, Greenville NC, Roanoke VA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 30

Code: NCT04322318

Phase2, Recruiting

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Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for
Classic Follicular Lymphoma,
Location: Durham NC, Chapel Hill NC, Goldsboro NC, Clinton NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06337318

Phase3, Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase2, Recruiting

Proton or Photon RT for Retroperitoneal Sarcomas

for
Retroperitoneal Sarcoma
Location: Durham NC, Buffalo NY, Boston MA, Chicago IL,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT01659203

Phase1, Phase2, Recruiting

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

for
Dravet Syndrome
Location: Durham NC, Morrisville NC, Winston-Salem NC,
Sponsor: Epygenix

Sex: All

Age: 2+

Code: NCT04462770

Phase3, Recruiting

US National OCS Heart Perfusion (OHP) Registry

for
Heart Transplant
Location: Durham NC, Chapel Hill NC, Charlotte NC, Richmond VA,
Sponsor: TransMedics

Sex: All

Age: 0+

Code: NCT05915299

Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for
Metastatic Renal Cell Carcinoma,
Location: Durham NC, Chapel Hill NC, Cary NC, Raleigh NC,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05327686

Phase2, Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Durham NC, Chapel Hill NC, Cary NC, Raleigh NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05987241

Phase2, Phase3, Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 22

Code: NCT04726241

Phase1, Phase2, Recruiting

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for
Progressive Pulmonary Fibrosis, Interstitial Lung Disease
Location: Durham NC, Greensboro NC, Winston-Salem NC,
Sponsor: United Therapeutics

Sex: All

Age: 18+

Code: NCT05943535

Phase3, Recruiting

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

for
Metastatic Small Intestinal Adenocarcinoma,
Location: Durham NC, Cary NC, Raleigh NC, Albemarle NC,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04205968

Phase2, Recruiting

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for
Central Nervous System Nongerminomatous Germ Cell Tumor,
Location: Durham NC, Winston-Salem NC, Greenville NC, Roanoke VA,
Sponsor: Children's Oncology Group

Sex: All

Age: 3 - 29

Code: NCT04684368

Phase2, Recruiting

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 5 - 60

Code: NCT05675410

Phase3, Recruiting

Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Durham NC, Raleigh NC, Cary NC, Kinston NC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 0+

Code: NCT04242095

Recruiting

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Durham NC, Chapel Hill NC, Richmond VA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 60+

Code: NCT05976763

Phase3, Recruiting

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

for
Advanced Non-Small Cell Lung Cancer,
Location: Durham NC, Richmond VA, Lexington KY, Fairfax VA,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT04613596

Phase2, Phase3, Recruiting