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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Targeted Pediatric High-Grade Glioma Therapy

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma,
Location: Durham NC, Washington D.C. DC, Columbus OH,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 1 - 39

Code: NCT05839379

Recruiting

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

for
Pediatric Intestinal Failure
Location: Durham NC, Ann Arbor MI, Hartford CT, Toronto,
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 25

Code: NCT04629014

Recruiting

Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

for
Cervical Deformity
Location: Durham NC, Charlottesville VA, Baltimore MD,
Sponsor: International Spine Study Group Foundation

Sex: All

Age: 18+

Code: NCT04194996

Recruiting

The WISER Study: Web Based Methods for Enhancing Resilience

for
Burnout
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05636072

Recruiting

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

for
Pediatric Sarcoma, Refractory, Pediatric Sarcoma, Relapsed
Location: Durham NC, Chapel Hill NC, Charlotte NC,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 2 - 40

Code: NCT05634369

Phase1, Phase2, Recruiting

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Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

for
Fear, GAD, Emotional Memory, PTSD
Location: Durham NC, Los Angeles CA
Sponsor: Duke University

Sex: All

Age: 18 - 70

Code: NCT05120635

Recruiting

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma
Location: Durham NC, Washington D.C. DC, Philadelphia PA,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 0 - 21

Code: NCT04655404

Early_phase1, Recruiting

Study of Olutasidenib and Temozolomide in HGG

for
High Grade Glioma, Astrocytoma, Astrocytoma, Grade III,
Location: Durham NC, Columbus OH, Cincinnati OH, Chicago IL,
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 12 - 39

Code: NCT06161974

Phase2, Recruiting

Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy-SUMMIT

for
Duchenne Muscular Dystrophy
Location: Durham NC, Charlotte NC, Charlottesville VA, Hershey PA,
Sponsor: Catalyst Pharmaceuticals, Inc.

Sex: Male

Age: 2+

Code: NCT06564974

Recruiting

Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

for
Post Traumatic Stress Disorder
Location: Durham NC, Carrollton GA, Piscataway NJ, New York NY,
Sponsor: University of Michigan

Sex: All

Age: 18+

Code: NCT05751473

Recruiting

SC2i Tissue and Data Repository Protocol

for
Critical Illness
Location: Durham NC, Bethesda MD, Atlanta GA
Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

Sex: All

Age: 18+

Code: NCT02182180

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

for
Dravet Syndrome
Location: Durham NC, Ann Arbor MI, Chicago IL, Miami FL,
Sponsor: Encoded Therapeutics

Sex: All

Age: 0 - 17

Code: NCT05419492

Phase1, Phase2, Recruiting

REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants

for
Symptomatic Venous Thromboembolism (VTE)
Location: Durham NC, Raleigh NC, Roanoke VA, Wilmington NC,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07213778

Phase3, Recruiting

Ultrasound Simulation Case-based Workshop Implementation and Impact Assessment

for
Point-of-care Ultrasound, Simulation Training,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06960837

Recruiting

Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia

for
Knee Stiffness After Total Knee Arthroplasty
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT07348614

Recruiting

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

for
Ulcerative Colitis, Pediatric, Inflammatory Bowel Diseases,
Location: Durham NC, Chapel Hill NC, Charlotte NC, Pittsburgh PA
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 1 - 18

Code: NCT07198113

Recruiting

Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

for
Cardiovascular Disease Acute, Emergency Department Patient,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07159269

Recruiting

Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

for
GRIN-related Neurodevelopmental Disorder
Location: Durham NC, Washington D.C. DC, Philadelphia PA,
Sponsor: GRIN Therapeutics, Inc.

Sex: All

Age: 0 - 18

Code: NCT07224581

Phase3, Recruiting

Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

for
Metastatic Ewing Sarcoma
Location: Durham NC, Columbus OH, The Bronx NY, Nashville TN,
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 1+

Code: NCT07194044

Phase1, Recruiting

Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

for
Duchenne Muscular Dystrophy (DMD), Cardiomyopathy,
Location: Durham NC, Richmond VA, Washington D.C. DC, Columbus OH,
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 0+

Code: NCT07674758

Recruiting