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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for
Ganglioneuroblastoma, Nodular, Neuroblastoma
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 30

Code: NCT06172296

Phase3, Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Durham NC, Chapel Hill NC, Cary NC, Raleigh NC,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05624996

Phase3, Recruiting

Project: Every Child for Younger Patients With Cancer

for
Adrenal Gland Pheochromocytoma, Carcinoma In Situ,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT02402244

Recruiting

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for
Metastatic Malignant Neoplasm in the Lung,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 50

Code: NCT05235165

Phase3, Recruiting

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

for
Cigarette Smoking-Related Carcinoma
Location: Durham NC, Greensboro NC, Kernersville NC, Goldsboro NC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT05008848

Phase3, Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for
Acute Myeloid Leukemia
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT04293562

Phase3, Recruiting

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for
Refractory Differentiated Thyroid Gland Carcinoma
Location: Durham NC, Chapel Hill NC, Charleston SC, Baltimore MD,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT06475989

Phase3, Recruiting

Immunomodulation to Optimize Vascularized Composite Allograft Integration for Limb Loss Therapy

for
Immunosuppression
Location: Durham NC
Sponsor: Linda Cendales

Sex: All

Age: 18 - 65

Code: NCT02310867

Phase2, Recruiting

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC, Roanoke VA,
Sponsor: Children's Oncology Group

Sex: Female

Age: 0 - 39

Code: NCT06513962

Phase3, Recruiting

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for
Malignant Female Reproductive System Neoplasm,
Location: Durham NC, Raleigh NC, Burlington NC, Reidsville NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06126276

Phase2, Recruiting

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for
Acute Leukemia of Ambiguous Lineage,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 1

Code: NCT06317662

Phase2, Recruiting

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for
Atrial Fibrillation, Stroke, Bleeding
Location: Durham NC, Greenville NC, Charlottesville VA,
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18+

Code: NCT04045665

Phase3, Recruiting

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

for
Pleural Biphasic Mesothelioma, Pleural Sarcomatoid Mesothelioma
Location: Durham NC, Raleigh NC, Jacksonville FL, Danville IL,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT05647265

Phase2, Recruiting

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC),
Location: Durham NC, Chapel Hill NC, Cary NC, Raleigh NC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06661720

Phase3, Recruiting

Optimizing PreTerm Infant Ampicillin Dosing

for
Early Onset Sepsis, Preterm Neonates, NICU, Ampicillin,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 0

Code: NCT07610486

Phase1, Phase2, Recruiting

Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and the Environment

for
Smoking
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 21+

Code: NCT07089901

Recruiting

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Durham NC, Baltimore MD, Lexington KY, Philadelphia PA,
Sponsor: Clasp Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06778863

Phase1, Recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

for
Endometrial Cancer
Location: Durham NC, Pinehurst NC, Richmond VA, Fairfax VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06952504

Phase3, Recruiting

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

for
Advanced Cancer, Metastatic Cancer
Location: Durham NC, Miami FL
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06174987

Phase3, Recruiting

Cord Clamping Among Neonates With Congenital Heart Disease

for
Congenital Heart Disease (CHD)
Location: Durham NC, Columbia SC, Baltimore MD, Philadelphia PA,
Sponsor: Carl Backes, MD

Sex: All

Age: 0

Code: NCT06153459

Recruiting