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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

for
Prostate Cancer, Prostate Adenocarcinoma,
Location: Durham NC, New York NY, Madison WI
Sponsor: Duke University

Sex: Male

Age: 18+

Code: NCT06141993

Recruiting

AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Durham NC, Detroit MI, Chicago IL, Dallas TX,
Sponsor: Novacea

Sex: All

Age: 18+

Code: NCT00394628

Phase1, Phase2, Recruiting

A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS

for
AML, Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia,
Location: Durham NC, Fairfax VA, Tyler TX, Dallas TX, Houston TX,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18+

Code: NCT04358393

Phase1, Phase2, Recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Durham NC, Winston-Salem NC, Greenville NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554393

Phase2, Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Location: Durham NC, Roanoke VA, Charlotte NC, Richmond VA,
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT04031677

Phase3, Recruiting

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Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Durham NC, Ann Arbor MI, Madison WI, Los Angeles CA,
Sponsor: Syntrix Biosystems, Inc.

Sex: Male

Age: 18+

Code: NCT06228053

Phase2, Recruiting

Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Durham NC, Charleston SC, St Louis MO, Houston TX
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05793151

Recruiting

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

for
Mild Cognitive Impairment (MCI), Cognitive Training
Location: Durham NC, New York NY, Miami FL, Seattle WA
Sponsor: Columbia University

Sex: All

Age: 55 - 70+

Code: NCT06601933

Phase2, Recruiting

A Study of Facilitators and Barriers to Improve Acute Kidney Injury in Children Through Mobile Health Intervention

for
Acute Kidney Injury
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 1 - 18

Code: NCT04403633

Recruiting

Follow-up Visit of High Risk Infants

for
Infant, Newborn, Infant, Low Birth Weight,
Location: Durham NC, Philadelphia PA, Atlanta GA, Cincinnati OH,
Sponsor: NICHD Neonatal Research Network

Sex: All

Age: 1 - 2

Code: NCT00009633

Recruiting

QTX3034 in Patients With KRAS G12D Mutation

for
Solid Tumors
Location: Durham NC, Fairfax VA, New York NY, The Bronx NY,
Sponsor: Quanta Therapeutics

Sex: All

Age: 18+

Code: NCT06227377

Phase1, Recruiting

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

for
Complex Congenital Heart Defect, Dysfunctional RVOT Conduit,
Location: Durham NC, Charlottesville VA, Pittsburgh PA,
Sponsor: Edwards Lifesciences

Sex: All

Age: 0+

Code: NCT02744677

Recruiting

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

for
Heart Failure With Preserved Ejection Fraction (HFpEF
Location: Durham NC, Charleston SC, Columbus OH, New York NY,
Sponsor: Axon Therapies, Inc.

Sex: All

Age: 40+

Code: NCT04592445

Recruiting

Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy

for
Cancer Weight Loss
Location: Durham NC, Charlottesville VA, Atlanta GA, New York NY,
Sponsor: Endevica Bio

Sex: All

Age: 18+

Code: NCT06937177

Phase2, Recruiting

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

for
Non-Small Cell Lung Cancer (NSCLC)
Location: Durham NC, Pinehurst NC, Asheville NC, Newark DE,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT05920356

Phase3, Recruiting

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for
Low Grade Astrocytoma, Low Grade Glioma,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2 - 21

Code: NCT04166409

Phase3, Recruiting

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

for
Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis,
Location: Durham NC, Chapel Hill NC, Boston MA, Milwaukee WI,
Sponsor: UCB Biopharma SRL

Sex: Female

Age: 18+

Code: NCT06888193

Phase1, Recruiting

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

for
Metastatic Uveal Melanoma, Cutaneous Melanoma,
Location: Durham NC, Philadelphia PA, Cincinnati OH, Nashville TN,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT03947385

Phase1, Phase2, Recruiting

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

for
Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen,
Location: Durham NC, Baltimore MD, Pittsburgh PA, Atlanta GA,
Sponsor: Servier Bio-Innovation LLC

Sex: All

Age: 18+

Code: NCT06127407

Phase3, Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for
B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 25

Code: NCT03959085

Phase3, Recruiting