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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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GERD in Children With Cystic Fibrosis

for
GERD in Children, Cystic Fibrosis in Children
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 2 - 18

Code: NCT06617013

Recruiting

An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

for
Lennox Gastaut Syndrome
Location: Durham NC, Morrisville NC, Charlotte NC,
Sponsor: Epygenix

Sex: All

Age: 2 - 55

Code: NCT05066217

Phase3, Recruiting

Anesthetics and Analgesics in Children

for
Anesthesia, Pain
Location: Durham NC, Charleston SC, Toronto, Chicago IL,
Sponsor: Chi Dang Hornik

Sex: All

Age: 0 - 17

Code: NCT03427736

Recruiting

A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

for
Epilepsy, Temporal Lobe
Location: Durham NC, Winston-Salem NC, Charlotte NC,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06422923

Phase1, Phase2, Recruiting

A Study of TYRA-300 in Children With Achondroplasia: BEACH301

for
Achondroplasia
Location: Durham NC, Chevy Chase MD, Baltimore MD, Wilmington DE,
Sponsor: Tyra Biosciences, Inc

Sex: All

Age: 3 - 10

Code: NCT06842355

Phase2, Recruiting

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A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)

for
Gram-negative Bacterial Infection
Location: Durham NC, Louisville KY, Indianapolis IN, Boston MA,
Sponsor: Pfizer

Sex: All

Age: 0

Code: NCT06462235

Phase2, Recruiting

Cooperative Huntington's Observational Research Trial

for
Huntington Disease
Location: Durham NC, Winston Salem NC, Charlottesville VA,
Sponsor: HP Therapeutics Foundation

Sex: All

Age: 0+

Code: NCT00313495

Recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

for
Acquired Antithrombin Deficiency
Location: Durham NC, Winston-Salem NC, Columbus OH, Toronto,
Sponsor: Octapharma

Sex: All

Age: 18 - 70+

Code: NCT06096116

Phase3, Recruiting

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for
Hypoplastic Left Heart Syndrome (HLHS)
Location: Durham NC, Charlotte NC, Charlottesville VA,
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0 - 1

Code: NCT02852031

Recruiting

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Durham NC, Washington D.C. DC, Baltimore MD,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05384626

Phase1, Phase2, Recruiting

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for
Graft-versus-host Disease (GVHD)
Location: Durham NC, Chapel Hill NC, Charlotte NC, Richmond VA,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT06615050

Phase3, Recruiting

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

for
Shoulder Surgery, Shoulder Pain, Shoulder Injuries,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT04209504

Recruiting

Neuromodulation of Memory in Aging

for
Mild Cognitive Impairment, MCI
Location: Durham NC
Sponsor: Indiana University

Sex: All

Age: 18 - 70+

Code: NCT05460468

Recruiting

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for
Ischemic Stroke, Intracerebral Hemorrhage,
Location: Durham NC, Charlottesville VA, Baltimore MD,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT04916210

Recruiting

Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction

for
Heart Failure
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06733012

Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for
Metastatic Breast Cancer
Location: Durham NC, Baltimore MD, Atlanta GA, Columbus OH,
Sponsor: LeonaBio

Sex: All

Age: 18+

Code: NCT05696626

Phase3, Recruiting

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for
Heart Failure, Heart Failure With Reduced Ejection Fraction
Location: Durham NC, Chapel Hill NC, Cary NC, Greensboro NC,
Sponsor: Cytokinetics

Sex: All

Age: 18 - 70+

Code: NCT06736574

Phase3, Recruiting

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for
Spinal Muscular Atrophy (SMA)
Location: Durham NC, Richmond VA, Charlottesville VA, Norfolk VA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04174157

Recruiting

US National OCS Liver Perfusion (OLP) Registry

for
Liver Transplant
Location: Durham NC, Charlotte NC, Lexington KY, Philadelphia PA,
Sponsor: TransMedics

Sex: All

Age: 0+

Code: NCT05940857

Recruiting

Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

for
Hyperkalemia
Location: Durham NC, Augusta GA, Philadelphia PA, Nashville TN,
Sponsor: Vifor Pharma, Inc.

Sex: All

Age: 0 - 11

Code: NCT05766839

Phase2, Recruiting